Clinical trials: Genicular Nerve Block
Knee Pain Chronic
A Comparison of Ultrasound Guided Genicular Nerve Blockade Using Current Versus Revised Anatomical Targets
comparison of effectiveness of ultrasound guided genicular nerve blockades and radio frequency stimulation
- Trial name
- NCT05073887
- Testing
- Current Targets
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Diskapi Teaching and Research Hospital
Knee Osteoarthritis, Knee Pain Chronic
The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain…
- Trial name
- NCT06239649
- Testing
- Genicular nerve Radiofrequency Ablation block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Osteoarthritis (OA) of the Knee, Total Knee Arthroplasty
GENicular Nerve Block in KNEE Arthroplasty
The goal of this clinical trial is to learn whether a preoperative genicular nerve block (GNB) can reduce pain after knee replacement surgery in adults with knee osteoarthritis (OA) undergoing total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis (OA) of the Knee, Total Knee Arthroplasty, Genicular Nerve Block
- Trial name
- GENKNEE (NCT07589127)
- Testing
- Preoperative genicular nerve block (GNB)
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Helse Møre og Romsdal HF
Post Operative Pain
Efficacy of Bupivacaine-magnesium Combination Versus Bupivacaine Alone in Genicular Nerve Block
It is proved that the addition of magnesium sulfate to local anesthetics for neuraxial anesthesia improves the quality of analgesia and prolongs the duration of anesthesia .
- Trial name
- NCT06520475
- Testing
- genicular nerve block using bupivacaine and magnesium, genicular nerve block using bupivacaine and normal saline
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Cairo University
Pain, Postoperative, Knee Pain Chronic
Ultrasound-guided Genicular Nerve Block for Total Knee Arthroplasty (GenTKR)
Knee Osteoarthritis affects one third of the population over 65 years old. Total knee arthroplasty (TKA) has become one of the most frequent surgical procedures in the world.
- Trial name
- GenTKR (NCT04024319)
- Testing
- Genicular Nerve Block
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Clinic of Barcelona
Nerve Block, Regional Anaesthesia
A Comparative Study of Combined Adductor Canal and Interspace Between Popliteal Artery and Knee Capsule Versus Combined Adductor Canal and Genicular Nerve in Total Knee Arthroplasty
The aim of this study is to investigate the effectiveness of combined adductor canal block (ACB) with interspace between popliteal artery and the knee capsule (IPACK) versus combined ACB with genicular nerve block (GNB) for…
- Trial name
- NCT06864663
- Testing
- nerve block with bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Analgesia, Total Knee Arthroplasty
GENIFEM Trial: Postoperative Pain After Total Knee Arthroplasty (TKA)
Motor-sparing analgesic interventions for patients undergoing total knee arthroplasty (TKA) are a key component of fast-track surgery.
- Trial name
- GENIFEM (NCT05156476)
- Testing
- Genicular nerve block-iPACK group, Femoral triangle block-iPACK group, Local infiltration analgesia
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Ziekenhuis Oost-Limburg
Knee Osteoarthritis
Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis
Knee arthritis is a chronic joint disease that causes pain, disability and impaired quality of life, leading to significant social and health problems worldwide.
- Trial name
- NCT06903936
- Testing
- Group 1: GNB (GENICULAR NERVOUS NERVOUS BLOCK) group:, Group 2: PT (PHYSICAL THERAPY) group, Group 3: Exercise group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Osteo Arthritis Knee, Osteoarthritis
The Impact of Genicular Nerves Chemical Neurolysis on the Quality of Life of Patients with Advanced Knee Osteoarthritis.
Genicular nerves chemical neurolysis in advanced osteoarthritis of the knee joint.
- Trial name
- NCT06087601
- Testing
- 0.9% Sodium chloride, 95% ethanol
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Knee Arthroplasty, Total
Comparison Between Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block
The purpose of this study is to compare the analgesic outcomes (time to first analgesic request, total amount of analgesic consumption, and pain scores) following total knee arthroplasty by either combined biceps femoris short…
- Trial name
- NCT07418307
- Testing
- Combined biceps femoris short head block and adductor canal block, Genicular nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Postoperative Pain, Knee Surgery
Comparison of Nerve Blocks for Pain Relief After Knee Surgery
This retrospective observational study compares the postoperative analgesic effectiveness of ultrasound-guided fascia iliaca compartment block (FICB) with combined IPACK and genicular nerve block (GNB) in patients undergoing knee…
- Trial name
- NCT07845591
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block, Ultrasound-Guided Combined IPACK and Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Post Operative Pain Control
Evaluation of the Role of Genicular Nerve Block When Combined With Adductor Canal Block for Pain Control Following Knee Arthroscopy
The intervention tests the efficacy of Genicular nerve block when combined with Adductor canal block in comparison with Adductor canal block alone to control post operative pain in knee arthroscopy
- Trial name
- NCT06951204
- Testing
- Adductor Canal Block (ACB) Only, Adductor canal block (ACB) combined with Genicular nerve block (GNB)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis, Chronic Knee Pain
Sonographic Thigh Adjustment Ratio and Subcutaneous Fat Thickness as Predictors of Genicular Nerve Block Response in Knee Osteoarthritis
Knee osteoarthritis (KOA) is a leading cause of chronic pain and disability. Although genicular nerve block (GNB) is an effective treatment for many patients, treatment response varies considerably.
- Trial name
- STAR-GNB (NCT07712419)
- Testing
- Ultrasound-Guided Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
3-Needle, 5-Needle
3-Needle vs 5-Needle of Genicular Nerve Block on Pain and Quality of Life in Knee Osteoarthritis
This study aims to compare the 3-needle and 5-needle of genicular nerve block on pain and quality of life in Knee osteoarthritis (KOA).
- Conditions
- 3-Needle, 5-Needle, Genicular Nerve Block, Pain
- Trial name
- NCT07853170
- Testing
- 3-nerve-targeted group, 5-nerve-targeted group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Postoperative Pain
Depomedrol for Genicular Nerve Block.
This study is designed to test the efficacy of adding Depomedrol a long-acting steroid to bupivacaine for relieving postoperative pain and reducing opioid requirements following total knee replacement surgery.
- Trial name
- NCT05893771
- Testing
- Methylprednisolone Injection, Bupivacaine Hcl 0.5% Inj_#2, normal saline
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Menoufia University
Knee Osteoarthritis
A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain
There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA).
- Trial name
- SKOAP (NCT04504812)
- Testing
- Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks
- Where
- 24 sites in United States
- Volunteers
- 1,937 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Knee, Pain
Diagnostic Genicular Nerve Block Prior to Radiofrequency Ablation for Knee Osteoarthritis Pain
Chronic painful knee OA is a major cause of disability in older adults. In patients whose symptoms are refractory to conservative management but who do not wish to undergo TKA or, alternatively, are not operative candidates…
- Conditions
- Osteoarthritis, Knee, Pain, Nerve; Lesion
- Trial name
- NCT02578108
- Testing
- genicular nerve diagnostic block with lidocaine (local anesthetic), genicular nerve radiofrequency ablation
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Northwestern University
Total Knee Arthroplasty
Analgesic Effect of Adductor Canal Block, IPACK Block, and Genicular Nerve Block
Patients with total knee arthroplasty (TKA) experience severe postoperative pain. This reduces patient satisfaction, delays mobility, and prolongs hospital stay.
- Trial name
- NCT06686095
- Testing
- Group Adductor canal block, Group Genicular Nerve Block, Group IPACK Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hitit University
Post Operative Pain
Comparison Between Two Blocks in Analgesia After Knee Arthroplasty
Comparative Study between Adductor canal block combined with infiltration OF The interspace between popliteal artery and the capsule of the knee block versus genicular nerves Block combined with IPACK in Postoperative analgesia…
- Trial name
- NCT07046377
- Testing
- ACB - IPACK, GNB - IPACK
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Total Knee Replacement, Genicular Nerve Block
Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty
The goal of this randomized controlled trial is to examine if there is a relationship between the addition of the genicular nerve block and anterior femoral cutaneous nerve block in providing analgesia and the use of oral and…
- Conditions
- Total Knee Replacement, Genicular Nerve Block, Opioid Use
- Trial name
- NCT05980546
- Testing
- Bupivacaine Injection, Dexamethasone injection, Fentanyl
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- Hospital for Special Surgery, New York