Clinical trials: Gender, open to volunteers
Fragile X Syndrome, Autism Spectrum Disorder
Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders
Fragile X Syndrome (FXS) is a complex neurodevelopmental disorder caused by a mutation on the X chromosome. Scientists have investigated FXS extensively in both humans and animals.
- Conditions
- Fragile X Syndrome, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- ENTRAIN (NCT06227780)
- Testing
- Alpha Auditory Entrainment
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Failure
Heart Failure in Women: Epidemiological and Prognostic Insights
Heart failure (HF) is a leading cause of hospital admission in older adults and women account for more than half of these admissions, yet they remain under-represented in prospective HF cohorts.
- Trial name
- HER-HF (NCT07847983)
- Where
- 24 sites in Spain
- Volunteers
- 430 people
- Sponsor
- Carolina Ortiz Cortes
HIV Prevention, Substance Use
Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study
This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- HAMMOCK (NCT07512869)
- Testing
- Self-administered questionnaire assessment, Semi-structured in-depth interviews (IDIs), Development and refinement of harm reduction model
- Where
- Thailand
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of atumelnant treatment in pediatric participants with classic congenital adrenal hyperplasia (CAH).
- Trial name
- NCT07159841
- Testing
- Atumelnant
- Where
- 52 sites in United States, Argentina and 11 more
- Volunteers
- 153 people
- Sponsor
- Crinetics Pharmaceuticals Inc.
Acute Coronary Syndrome, Gender
Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome
Create a multicenter prospective registry that collects information from women affected by acute coronary syndrome (ACS). This registry aims to understand the diversity in the presentation of women with ACS.
- Conditions
- Acute Coronary Syndrome, Gender, Genetic Predisposition
- Trial name
- ACS GEDI (NCT06441942)
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
HIV Prevention, Substance Use
Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in Thailand
The study evaluates the integration of a sexual pleasure-based approach into harm reduction services for MSM and transgender persons engaging in chemsex or substance use in Thailand, using the "Pleasuremeter" tool to improve…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- PLEASURE (NCT07509853)
- Testing
- Pleasuremeter-guided qualitative interview, Pleasuremeter-based sexual pleasure discussion integrated with harm reduction services
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis
STI Prophylaxis and Emergence of Antimicrobial Resistance
The goal of this observational study is to understand the risk of antibiotic resistance and changes in the human microbiome (bacteria that live inside and on us), if people use antibiotics to prevent sexually transmitted…
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis, Antibiotic Resistance, Bacterial, Microbiome
- Trial name
- SPEAR (NCT06778083)
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University College, London
Heart Failure, Acute Heart Failure
Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?
The goal of this clinical trial is to learn whether a rapid and intensive optimization of heart failure medications in women can improve outcomes after hospitalization for heart failure.
- Conditions
- Heart Failure, Acute Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PopS-HF (NCT07295522)
- Testing
- Guideline-Directed Medical Therapy (GDMT)
- Where
- 12 sites in Italy
- Volunteers
- 368 people
- Sponsor
- IRCCS Policlinico S. Donato
Compulsive Sexual Behavior
Yoga Intervention for Compulsive Sexual Behavior Disorder
Yoga intervention as a complementary and integrative treatment for compulsive sexual behavior disorder (CSBD). The hypothesis is that participants with CSBD, after being submitted to the protocol of the yoga intervention group in…
- Trial name
- CSBD (NCT04634175)
- Testing
- Yoga intervention
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Gender Prediction, Dating Violence
Comparison of Escape Room and Branching Scenario Games in Nursing Education
The aim of this study is to examine the effects of a web-based escape room (EQUITY-ROOM) and a web-based branching scenario (EQUITY-PATH) simulation added to standardized video-based education on nursing students' gender…
- Conditions
- Gender Prediction, Dating Violence, Nursing Education
- Trial name
- NCT07886086
- Testing
- EQUITY-ROOM (Web-based Escape Room Game), EQUITY-PATH (Web-based Branching Scenario Game), Standardized Video-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Gender Dysphoria, Adult
Gender Affirming Vaginoplasty With Tubularized Augmented Peritoneal Cap (TAPCap) Utilizing Fish Skin Xenograft (Kerecis™)
Bottom gender affirming surgery is one of the key steps towards aligning the physical appearance and gender identity in transgender women.
- Trial name
- NCT07286123
- Testing
- Tubularized augmented peritoneal cap vaginoplasty, Biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University Hospitals Cleveland Medical Center
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Shame, Intimate Partner Violence
How a Resilience-Focused Intervention is Perceived by Women Subjected to Domestic Violence
At Uppsala University Hospital, there is an outpatient clinic for women subjected to intimate partner violence. In order to explore how patients experience the biopsychosocial resilience-based intervention in use at the clinic…
- Conditions
- Shame, Intimate Partner Violence, Domestic Violence Exposure, Resilience, Psychological
- Trial name
- EMBER-2 (NCT07235722)
- Testing
- Qualitative interview
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Pain, Abuse, Drug
Age-dependent Effects of Smoked and Oral Delta-9-THC
This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.
- Conditions
- Pain, Abuse, Drug, Intoxication; Cannabinoids
- Trial name
- SAGE (NCT05865470)
- Testing
- Cannabis, Dronabinol
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postpartum Depression
Postpartum 1-Day CBT Pilot Study (Türkiye)
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effects of a culturally adapted, one-day online Cognitive Behavioral Therapy (CBT)-based group workshop for women with…
- Trial name
- NCT07267702
- Testing
- One-Day Online CBT-Based Workshop
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Stage I Testicular Seminoma, Stage I Testicular Nonseminomatous Germ Cell Tumor
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
This is a multicenter, interventional, randomized study among adult patients recently diagnosed with a rare tumor (<12 months). The study will aim to compare compliance with the personalized post-treatment surveillance plan…
- Conditions
- Stage I Testicular Seminoma, Stage I Testicular Nonseminomatous Germ Cell Tumor, Gastrointestinal Stromal Tumors, Ovarian Germ Cell Tumor
- Trial name
- SUR-CAN (NCT05500391)
- Testing
- Oncological Follow-up
- Where
- 3 sites in France
- Volunteers
- 88 people
- Sponsor
- Centre Oscar Lambret
Bacterial Sexually Transmitted Diseases
Doxycycline Intervention for Bacterial STI ChemoprOphylaxis (DISCO)
There is a growing epidemic of the bacterial sexually transmitted infections (STIs) syphilis, chlamydia and gonorrhea worldwide; similarly concerning trends have been noted in Canada, where increases of over 160% have been seen…
- Trial name
- NCT04762134
- Testing
- Doxycycline Hyclate
- Where
- 6 sites in Canada
- Volunteers
- 560 people
- Sponsor
- Jonathan Troy Grennan
Education, Sex
Scaling Effective Behavioral Interventions With MPC Avatar-Based Virtual Training
The goal of this study is to learn if MPC: VISTA, an online training program, helps teachers and health educators deliver Making Proud Choices!, a program that helps teens lower their risk of pregnancy and HIV/STIs.
- Trial name
- MPC VISTA (NCT07880912)
- Testing
- MPC VISTA, Live Virtual Training
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- dfusion Inc