Clinical trials: Gastroscopy
Adverse Respiratory Events, Hypoxemia
Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy
Gastroscopy is important for diagnosing and treating upper gastrointestinal diseases in children. To ensure the procedure is safe and smooth, most children require sedation.
- Conditions
- Adverse Respiratory Events, Hypoxemia, Children, Gastroscopy
- Trial name
- NCT07748884
- Testing
- Fentanyl and Propofol, Esketamine and remimazolam
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Painless Gastroscopy Perioperative Sedation, Upper Gastrointestinal Tract Lesions
ED90 of Tegileridine Combined With Propofol For Painless Gastroscopy
This single-group, open-label, biased-coin up-and-down sequential dose-finding trial aims to determine the 90% effective dose (ED90) of intravenous tegileridine combined with fixed-dose propofol to eliminate body movement, cough…
- Trial name
- NCT07678411
- Testing
- Tegileridine combined with Propofol for gastroscopy
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Shiyou Wei
Gastroscopy, Barrett's Esophagus
Real-life Prospective Evaluation of Computer-aided Detection (CAD) of Barrett's Neoplasia
Barrett's oesophagus is a pre-cancerous condition in which normal cells in the lining of gullet undergo cell changes and this increases the risk of developing adenocarcinoma (a type of cancer) of the gullet.
- Trial name
- MetaVision (NCT05965921)
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Gastroscopy, Colonoscopy
A Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride in Gastroscopy/Colonoscopy
A total of 78 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 1:1:1 with etomidate as the control group, 26 cases in…
- Trial name
- NCT06682546
- Testing
- ET-26HCl 0.6mg/kg group, ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 3 sites in China
- Volunteers
- 78 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Gastroscopy
Evaluation of Gastric Volume and pH Changes in Gastroscopy Patients
Pulmonary aspiration is a rare but serious complication that can result in 57% mortality and 14% permanent damage. Fasting rules (solid foods 6-8 hours, clear liquids 2 hours) determined by anesthesia associations are applied to…
- Trial name
- NCT06842602
- Testing
- gum, candy, strict fasting rules
- Where
- Turkey (Türkiye)
- Volunteers
- 405 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Pediatric, Gastroscopy
Effect of Esketamine on 95% Induction Dose of Remimazolam
As an invasive operation, gastroscopy will cause children's nervousness, anxiety and uncooperative behavior, and even lead to the risk of bleeding and perforation, which will also affect the accuracy of the examination…
- Conditions
- Pediatric, Gastroscopy, ED95, Sedation
- Trial name
- EEIDR (NCT06303037)
- Testing
- Remimazolam besylate and low-dose Esketamine, Remimazolam besylate and Medium dose Esketamine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Sedation for Diagnostic Gastroscopy
Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial
Rationale Midazolam is known for its safety, effectiveness for procedural sedation during gastrointestinal (GI) endoscopy and is used as standard sedative by endoscopists worldwide.
- Trial name
- REST (NCT06614036)
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in Netherlands
- Volunteers
- 148 people
- Sponsor
- Koen Munters
Anastomotic Leak, Gastric Cancer
Anastomotic Leak Testing in Gastrectomy
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis.
- Conditions
- Anastomotic Leak, Gastric Cancer, Surgery, Testing, Reality
- Trial name
- NCT04292496
- Testing
- Introperative leak testing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanchong Central Hospital
Patients Requiring Diagnostic Gastroscopy With Sedation
A Single-centre Study of Entonox Versus Midazolam Sedation in Gastroscopy
This study aims to determine whether Entonox (gas and air) is at least as good as intravenous midazolam in providing analgesia and sedation during gastroscopy.
- Trial name
- NCT01744184
- Testing
- Entonox, Midazolam
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- The Royal Bournemouth Hospital
Diagnostic Gastroscopy
Intravenous Lidocaine to Reduce ED50 for Propofol Administered Using Target Controlled Infusion (TCI) During Gastroscopy
The goal of this prospective, interventionnal clinical trial is to assess if intravenous administration of linisol reduce the ED50 of propofol when administered using Target Controlled Infusion (TCI) during gastroscopy in healthy…
- Trial name
- NCT06143410
- Testing
- Lidocaine 2% Injectable Solution, Propofol injection, gastroscopy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Gastroscopy, Esophagogastroduodenoscopy
Performance of a Single-use Gastroscope (aScope Gastro) for Esophagogastroduodenoscopy
Several infectious outbreaks have been described in the literature as a result of contaminated endoscopes. These endoscopes cannot be sterilized and require an extensive cleaning process in which breaches of cleaning protocols…
- Conditions
- Gastroscopy, Esophagogastroduodenoscopy, Equipment Design, Equipment Contamination / Prevention & Control
- Trial name
- FARE (NCT05504434)
- Testing
- Single-use gastroscope
- Where
- 2 sites in Netherlands, Norway
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Diagnostic Gastroscopy
Intravenous Lidocaine to Reduce Propofol Consumption During Gastroscopy.
The goal of this clinical trial is to assess if intravenous administration of linisol reduce the propofol consumption and the sides effects of sedation during gastroscopy in healthy patients (ASA 1 and 2 patients).
- Trial name
- NCT05944887
- Testing
- Lidocaine 2% Injectable Solution, Propofol injection, gastroscopy
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Erasme University Hospital
Physicians Gastroscopy Training
How Effective Can a Simulator-Based Training Course For Beginners In Endoscopy Be Made?
The aim of the study is to clarify whether physicians training for gastroscopies benefit from a modified training course. The duration and type of optimized use of training simulators as part of a basic gastroscopy course can…
- Trial name
- EFFEKTRA (NCT04898803)
- Testing
- conventional DGVS training, extended simulator training
- Where
- 2 sites in Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Gastroscopy
Effect of Bispectral Index Monitoring (BIS) on Body Movement of Outpatients Undergoing Gastroscopy
Patients who meet the enrollment criteria were randomized 1:1 to either the BIS group or the OAA/S group. In the BIS group, the anesthesiologist set the target controlled infusion（TCI）parameters according to the patient's height…
- Trial name
- BIS (NCT05773807)
- Testing
- Bispectral index, Observer's assessment alert Sedation, Gastroscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Scheduled Gastroscopy Under Sedation
Endoscopist and Endoscope Motions During Digestive Endoscopy
The aim of the study is to record and analyze endoscopist and endoscope motions to identify key movements in flexible endoscopy.
- Trial name
- EndoMouv (NCT03458403)
- Testing
- Motions during gastroscopy
- Where
- France
- Volunteers
- 23 people
- Sponsor
- IHU Strasbourg
Gastroscopy
High Flow Nasal Cannula in Patients Undergoing Gastroscopy
During gastroscopy, the insertion of the fiberscope and gastric distension required to perform the examination may induce modifications to respiratory mechanics, respiratory effort and breathing pattern.
- Trial name
- NCT05693298
- Testing
- High Flow Nasal Cannula, Conventional Oxygen Therapy
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University Magna Graecia
Endoscopy, Education
Simulation-assisted Teaching in Learning Gastroscopy
This project is a single-blinded randomized controlled trial investigating the effect of simulation-based teaching in learning gastroscopy for medical doctors.
- Conditions
- Endoscopy, Education, Gastroscopy, Esophagogastroduodenoscopy
- Trial name
- NCT04247399
- Testing
- Simulation-based learning
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Anders Bo Nielsen
Gastroscopy, Feelings
Improve the Comfort, Safety and Quality of Upper Endoscopy by a Modified Fasting Protocol
This double-center, prospective, interventional study aims to include 200 gastroscopic procedures and investigate the relationship between fasting time and feeling of subjects.
- Conditions
- Gastroscopy, Feelings, Fasting
- Trial name
- NCT05219136
- Testing
- Modified Fasting Group, Conventional Fasting Group
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Gastroscopy Time, Early Gastric Cancer
Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors
This multicenter, prospective, interventional study aims to include 2000 gastroscopic procedures and investigate the relationship between procedure time and lesion detection rate in tertiary endoscopic centers in China.
- Conditions
- Gastroscopy Time, Early Gastric Cancer, Detection Rate
- Trial name
- NCT04602299
- Testing
- Set the minimum time of gastroscopy
- Where
- 2 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital