Clinical trials: Gastrointestinal Motility Disorder
Post Abdominal Surgery, Gastrointestinal Motility Disorder
Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility
Postoperative bowel motility is an important indicator of recovery after abdominal surgery and may be influenced by preoperative nutritional status.
- Conditions
- Post Abdominal Surgery, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- NCT07808281
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bahçeşehir University
Hysterectomy, Gastrointestinal Motility Disorder
Coffee Consumption After Laparoscopic Hysterectomy
Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols.
- Conditions
- Hysterectomy, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- COFFEE-LH (NCT07686510)
- Testing
- Postoperative Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Gastroesophageal Reflux, Esophageal Motility Disorders
High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux
This is a combined retro- and prospective, monocentric study. All patients who underwent or are planned for laparoscopic partial fundoplication (180° anterior or 270° posterior) between 2020-2023 are assessed for preoperative…
- Conditions
- Gastroesophageal Reflux, Esophageal Motility Disorders, Upper Gastrointestinal Disorder
- Trial name
- NCT05132816
- Testing
- high-resolution manometry
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Prof Urs Zingg
Gastrointestinal Motility Disorders in Children, Hirschsprung Disease
Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders.
- Conditions
- Gastrointestinal Motility Disorders in Children, Hirschsprung Disease, Constipation - Functional
- Trial name
- SMART-GUT (NCT07519915)
- Testing
- SNM/MRI/EMG
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders
BSGM to Evaluate Patients With GI Symptoms
The goal of this observational study is to learn about gastric myoelectric activity in children with GI symptoms. The main question it aims to answer is which patterns or signals are associated with GI symptoms as measured by a…
- Conditions
- Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders, Gastroparesis, Dyspepsia and Other Specified Disorders of Function of Stomach
- Trial name
- NCT05880199
- Testing
- Body surface gastric mapping device
- Where
- 5 sites in United States
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cirrhosis, Liver, Minimal Hepatic Encephalopathy
Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility
Small Intestinal Bacterial Overgrowth (SIBO) is a common and increasingly recognized disorder in cirrhosis (30% to 73%). One of the most important predisposing factors of SIBO is small bowel dysmotility.
- Conditions
- Cirrhosis, Liver, Minimal Hepatic Encephalopathy, Small Intestinal Bacterial Overgrowth, Gastrointestinal Motility Disorder
- Trial name
- NCT04244877
- Testing
- Rifaximin
- Sponsor
- MetroHealth Medical Center
Gastrointestinal Motility Disorder, Gastroparesis
IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serologic and/or endo organ…
- Conditions
- Gastrointestinal Motility Disorder, Gastroparesis, Neuropathy
- Trial name
- GAIN (NCT04208828)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Louisville
Systemic Sclerosis, Constipation
Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis
The purpose of this study is to determine whether transcutaneous electrical acustimulation (TEA) alters systemic sclerosis (SSc)-related colonic and anorectal physiology by enhancing autonomic nervous system (ANS) function.
- Conditions
- Systemic Sclerosis, Constipation, Gastrointestinal Motility Disorder, Autonomic Dysfunction
- Trial name
- TEA in SSc (NCT05989763)
- Testing
- Transcutaneous Electrical Acustimulation (TEA)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Defecation Disorder, Gastrointestinal Motility Disorder
"The Effect of Abdominal Massage on Gastrointestinal Functions in Mechanically Ventilated Patients Receiving Enteral Nutrition in Intensive Care"
This study aims to evaluate the effects of abdominal massage on gastrointestinal functions in mechanically ventilated patients receiving enteral nutrition in intensive care units.
- Conditions
- Defecation Disorder, Gastrointestinal Motility Disorder, Gastrointestinal Motility and Defecation Conditions
- Trial name
- AMGF-ICU (NCT06631001)
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Gastrointestinal System Disease, Functional Bloating
Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention
Abdominal bloating and distension (ABD) are the most commonly gastrointestinal symptoms reported by patients with various functional gut disorders such as functional dyspepsia, irritable bowel syndrome and it is frequently…
- Conditions
- Gastrointestinal System Disease, Functional Bloating, Distension; Bowel, Gastrointestinal Motility Disorder
- Trial name
- NCT06347367
- Testing
- Group 1 (exercise and self-manual approaches targeting only the diaphragm muscles), Group 2 (exercise and self-manual approaches targeting both diaphragm and core muscles)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Reflux Esophagitis, Gastroesophageal Reflux
A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis
A phase 2, randomized, double-blind, double-dummy, positive drug parallel controlled, multicenter trial to evaluate efficacy and safety of within 8 weeks (including 8 weeks) treatment of Anaprazole 40mg QD, 60mg QD compared with…
- Conditions
- Reflux Esophagitis, Gastroesophageal Reflux, Esophagitis, Esophageal Motility Disorders
- Trial name
- NCT05604261
- Testing
- Anaprazole sodium 40 mg, Anaprazole sodium 60 mg, Rabeprazole sodium 20 mg
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Xuanzhu Biopharmaceutical Co., Ltd.
Postoperative Pain, Gastrointestinal Motility Disorder
The Effect of Foot Reflexology After Cesarean Section
Standardized, quality and evidence-based nursing care after cesarean section is important to prevent or minimize complications that may occur after cesarean section.
- Trial name
- NCT05268328
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nülüfer Erbil
Gastrointestinal Motility Disorder
Intestinal Dysmotility in Patients With Functional Digestive Symptoms
Automatic and non-invasive diagnostic methods based on the analysis of internal (intraluminal) and external (abdominal) images have been recently developed to measure intestinal motility.
- Trial name
- NCT04764019
- Testing
- High resolution intestinal manometry
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Gastrointestinal Motility Disorder, Dyspepsia
The Effect of Prucalopride (Resolor®) on Gastric Motor Function and Gastric Sensitivity
Functional Dyspepsia-Postprandial Distress Syndrome (FD-PDS), is characterized by meal-related symptoms such as early satiation and postprandial fullness.
- Trial name
- NCT04429802
- Testing
- Prucalopride
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastrointestinal Motility Disorder
Gastrointestinal Motor Disorders (Esophageal and Anorectal) After COVID-19
The patients who had COVID-19 infection, and after that reported for one of the signs of gastrointestinal disorder (esophageal and anorectal) will be underwent to esophageal and anorectal motor monitoring investigation (HRM…
- Trial name
- NCT04988438
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University Hospital Dubrava
Functional and Motility Related Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia
A Pharmacy-based Study to Learn More About How Well Iberogast Works, How it Affects the Body, How it is Used, and User Satisfaction in Patients With Functional and Motility-related (Stomach and Bowel Movement-related) Gastrointestinal Diseases, Including Irritable Bowel Syndrome
Researchers want to learn more about the day-to-day use of Iberogast in people who have functional and motility-related gastrointestinal (stomach and bowel) diseases.
- Trial name
- NCT04993989
- Testing
- Iberogast (STW5, BAY98-7411)
- Where
- Germany
- Volunteers
- 843 people
- Sponsor
- Bayer
Preterm Infant, Feeding Disorder Neonatal
Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility
Mother's milk does not come in contact with the oropharyngeal pouch of preterm infants during gavage feeding. We hypothesized that stimulation of the oropharyngeal pouch using small amount of the mother's milk 5 minutes before…
- Conditions
- Preterm Infant, Feeding Disorder Neonatal, Gastrointestinal Motility Disorder
- Trial name
- OPAMM (NCT03552510)
- Testing
- Oro-pharyngeal Administration of Mother's Milk
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University Children Hospital
Gastrointestinal Motility Disorders
Safety and Efficacy Study of the FTRD System for Obtaining Full-thickness Intestinal Biopsies
The aim of this study is to evaluate FTRD (full-thickness resection device) in terms of obtaining full-thickness biopsies form the gastrointestinal tract endoscopically in the work-up of patients with gastrointestinal motility…
- Trial name
- NCT02673983
- Testing
- Endoscopic full-thickness biopsy
- Sponsor
- Region Skane
Gastrointestinal Motility Disorder, Intestinal Disease
Lanreotide in the Treatment of Small Bowel Motility Disorders
This is a human research study looking at the effectiveness of Lanreotide (study medication) in treating small bowel motility disorders.
- Trial name
- NCT03012594
- Testing
- Lanreotide
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Northwell Health
Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder
Gastrointestinal Motility Among Diabetes Patients
Gastrointestinal (GI) symptoms including vomiting, nausea, abdominal pain, constipation or chronic diarrhea affect a large number of patients with diabetes mellitus (DM).
- Conditions
- Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder, Diabetes Mellitus, Change of Transit or Circulation
- Trial name
- NCT02573519
- Testing
- 11C Donepezil PET/CT scan, 3D-Transit, 3D-Transit during treatment with Pyridostigmine
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus