Clinical trials: Gastroenterology
Hospitalized Adult Patients, Inpatient Internal Medicine Patients
A Dietitian-Driven Unified Nutritional Care Model (ADDUCE)
The goal of this clinical trial is to learn whether a new way of organising hospital nutrition care can improve outcomes for adults who are admitted to medical wards and are at risk of malnutrition.
- Conditions
- Hospitalized Adult Patients, Inpatient Internal Medicine Patients, Haematologic Disease, Pulmonary Diseases
- Trial name
- ADDUCE (NCT07730996)
- Testing
- Dietitian-driven nutritional care model, Current practice nutritional care
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Gødstrup Hospital
Eosinophilic Disorder, Eosinophilic Esophagitis (EoE)
New Cases of EoE in Children in Poland.
The aim of the study is to assess the incidence of EZP in Poland in the pediatric population and characteristics of Polish patients with EZP, i.e. their demographic, clinical, endoscopic and histological features.
- Conditions
- Eosinophilic Disorder, Eosinophilic Esophagitis (EoE), Eosinophilic Disease, Pediatric
- Trial name
- NCT07772388
- Testing
- Data collection
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Cardiology, Gastroenterology
Applying the Intention-Action Framework to Specialty Referrals
This is a prospective randomized controlled trial evaluating an EHR-embedded behavioral intervention intended to reduce low-value specialty referrals in cardiology, pulmonology, and gastroenterology.
- Conditions
- Cardiology, Gastroenterology, Pulmonology
- Trial name
- NCT07671976
- Testing
- Information provision, Auditing, Checklist
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- University of California, Los Angeles
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer
The goal of the study is: The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis.
- Conditions
- Barrett Esophagus, Barrett Esophagus Adenocarcinoma, Adenocarcinoma - GEJ, Gastroenterology
- Trial name
- Endeavor-2 (NCT07455422)
- Testing
- Risk profile disclosure
- Where
- 10 sites in Belgium, Denmark and 5 more
- Volunteers
- 266 people
- Sponsor
- University Hospital, Antwerp
Pancreatitis, Acute, Pain, Acute
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole.
- Conditions
- Pancreatitis, Acute, Pain, Acute, Pancreatic Disease, Pancreatic Diseases
- Trial name
- NCT07024199
- Testing
- The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- Medical University of Warsaw
Gastroenterology Surgery, Tube Feeding
Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing
This is a single-center prospective study evaluating the efficacy of a prototype gastrostomy anchor dressing for use with button gastrostomy tubes.
- Trial name
- Tube Anchor (NCT07115134)
- Testing
- Bearables Gastrostomy Tube Dressing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Children's National Research Institute
Gastroparesis, Functional Dyspepsia
Transauricular Vagal Nerve Stimulation; Functional Dyspepsia and Gastroparesis
The goal of this study is to establish parameters of gastric myoelectrical activity and heart rate variability in healthy human subjects and compare and contrast them to those with gastroparesis and functional dyspepsia, at…
- Conditions
- Gastroparesis, Functional Dyspepsia, Healthy, Digestive System Disease
- Trial name
- AVNS (NCT05405842)
- Testing
- Transauricular Vagal Nerve Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Gastroenterology, LARS - Low Anterior Resection Syndrome
A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome Patients
The purpose of this post-market clinical follow up study is to assess the efficacy on clinical symptoms of LARS of low volume Transanal Irrigation by MiniGo in conjunction with conservative treatment versus conservative treatment…
- Conditions
- Gastroenterology, LARS - Low Anterior Resection Syndrome, Rectal Cancer
- Trial name
- MINIGO (NCT06923150)
- Where
- 9 sites in France
- Volunteers
- 78 people
- Sponsor
- Qufora A/S
Gastroenterology
The Application of Remazolam in Gastroenteroscopy
OBJECTIVE: To study the safety, efficacy and clinical significance of remimazolam in the diagnosis and treatment of patients with daytime gastrointestinal endoscopy, calculate the optimal dose, and conduct relevant verification.
- Trial name
- NCT05357430
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Yangzhou University
Gastroenterology Surgery, Colorectal Surgery
Usability of myfood24 in Clinical Populations
Many patients would benefit from dietary/nutritional support to better manage their conditions but evaluating current intake in relation to personal targets is labour-intensive and often does not feature as part of clinical…
- Conditions
- Gastroenterology Surgery, Colorectal Surgery, Weight Loss, Weight Change, Body
- Trial name
- NCT04758559
- Testing
- myfood24, usual care
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Leeds
Gastroenterology
Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Japanese Persons
Interleukin (IL)-6 is a cytokine produced in response to infection and tissue damage. IL-6 is believed to act as a key mediator in chronic inflammation and autoimmune diseases such as inflammatory bowel diseases.
- Trial name
- NCT06515834
- Testing
- FE 999301
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Gastroenterology
A Randomized Clinical Trial of Shenbai Granules in Reducing Recurrence of Colorectal Adenoma
This study evaluates Shenbai Granules in Prevention of Colorectal Adenomatous Polyp Recurrence After Colonoscopy.Half of participants will receive Shenbai Granules,while the other half will receive a placebo.
- Trial name
- NCT03616444
- Testing
- Shenbai Granules
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Phlebotomy, Orthopedics
VR to Reduce Pain/Anxiety During Painful Procedures
This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing painful procedures in Phlebotomy, Radiology, Infusion, Orthopedics…
- Conditions
- Phlebotomy, Orthopedics, Radiology, Pain
- Trial name
- NCT04268901
- Testing
- Samsung Gear VR, Merge VR, Oculus Go
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Gastroenterology
Efficacy Evaluation of Dai Dai Flower on Body Weight
To assess the Dai Dai flower extract on body weight control
- Trial name
- NCT04692792
- Testing
- Dai Dai flower drink
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Gastroenterology & Work Related Injuries
Gastroenterology & Work Related Injuries
2.2.1. Primary Outcome(s) Percentage of gastroenterology fellows who have received any formal training in the ergonomics of endoscopy and how to prevent long term work related injuries. 2.2.2.
- Trial name
- NCT04216212
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Methodist Health System
Patient Diagnosed or Treated for Granulomatous Hepatitis Followed in the Internal Medicine (and or) Hepato-gastroenterology Departments
Lyon Granulomatous Hepatitis Study
Granulomatous hepatitis are histopathologically defined by the presence of epithelioid and gigantocellular granulomas within the hepatic parenchyma. Hepatic granulomas are observed in 2 to 15% of liver biopsies.
- Trial name
- LGH (NCT04459897)
- Testing
- Evaluation of epithelioid and gigantocellular granulomas within the hepatic parenchyma by histopathology approach.
- Where
- 3 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Gastroenterology, Lesions
Evaluation of Diagnostic Yield of EUS-Guided Tissue Sampling
All patients will receive standard medical care and no experimental interventions will be performed. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a well-established procedure commonly used for the…
- Trial name
- NCT02979509
- Testing
- Endoscopic ultrasound- (EUS) guided tissue sampling
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pediatric Outpatients Encountered in Three Specialty Clinics, i.e. Respirology, Gastroenterology, and Genito-urology
Effects of Expert Arbitration on Clinical Outcomes When Disputes Over Diagnosis Arise Between Physicians and Their Artificial Intelligence Counterparts: a Randomized, Multicenter Trial in Pediatric Outpatients
We have recently developed an artificial intelligence (AI) framework to diagnose common pediatric diseases. This randomized controlled clinical trial aims to investigate the effects of expert arbitration on clinical outcomes in…
- Trial name
- NCT04011761
- Testing
- expert arbitration over discordant diagnoses made by AI diagnostic system and human doctors, respectively
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Gastroenterology
Outcome of Colonoscopy Screening and Surveillance
With this study, we plan to review the performance of colonoscopy in colon cancer screening and surveillance, especially with the recent improvements in endoscopic technology (high definition endoscopes), use of split dose…
- Trial name
- NCT01827241
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Ambulatory Patients in the Dep. of Medical Gastroenterology, Ambulatory Patients in the Dep. of Gynecology
Outpatients' Knowledge About and Attitude Toward Randomised Clinical Trials
The purpose of this study is to investigate the knowledge about randomised clinical trials and the attitude towards clinical research among Danish outpatients.
- Conditions
- Ambulatory Patients in the Dep. of Medical Gastroenterology, Ambulatory Patients in the Dep. of Gynecology, Ambulatory Patients in the Dep. of Orthopedic Surgery, Ambulatory Patients in the Dep. of Urology
- Trial name
- INFO-I (NCT03094598)
- Testing
- Leaflet, Brochure, Booklet
- Where
- 2 sites in Denmark
- Volunteers
- 428 people
- Sponsor
- Copenhagen Trial Unit, Center for Clinical Intervention Research