Clinical trials: Gastro Intestinal Surgery
Surgical Adhesions, Intestinal Obstruction
Band Adhesions in Relation to Previous Abdominal Surgery
This study investigates the prevalence of previous abdominal surgery in a cohort of patients operated for bowel obstruction and analyzes the causes of obstruction discovered at surgery.
- Conditions
- Surgical Adhesions, Intestinal Obstruction, Surgery Induced Tissue Adhesions
- Trial name
- NCT03663023
- Testing
- Intestinal obstruction
- Volunteers
- 196 people
- Sponsor
- Göteborg University
Colostomy, Colorectal Neoplasm
A Randomized Trial on the Technical Aspects of Stoma Construction.
An investigation on the difference in stoma hernia frequency related to surgical technique when incising the fascia. All patients planned for elective colostomy formation are to be included.
- Conditions
- Colostomy, Colorectal Neoplasm, Diverticulitis
- Trial name
- NCT01694238
- Testing
- Cruciate incision, Circular incision, Mesh enforced cruciate incision
- Where
- Sweden
- Volunteers
- 209 people
- Sponsor
- Sahlgrenska University Hospital
Obesity, Weight Loss
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
The purpose of this registry study is to collect data through medical chart review and in patient visits on the efficacy and safety of various Endoscopic Bariatric therapies (EBTs).
- Conditions
- Obesity, Weight Loss, Gastro Esophageal Reflux, Bariatric Surgery Candidate
- Trial name
- EBT (NCT04494048)
- Testing
- Endoscopic Bariatric Therapies
- Where
- United States
- Volunteers
- 9,999 people
- Sponsor
- Weill Medical College of Cornell University
Colorectal Neoplasms
ICG-coated Endoscopic Clip for Tumor Localization
The fluorescent clipping method involves endoscopic clipping a fluorescent clip into the colonic lesion site in advance of surgery, and observing the position of the fluorescence through the colonic wall by a light source of a…
- Trial name
- NCT03924349
- Testing
- ICG-coated clip
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- National Cancer Center, Korea
Rectal Cancer
Introduction and Influence of Total Mesorectal Excision (TME) in the Treatment of Rectal Cancer
Total mesorectal excision (TME) is a rather new operation technique in the treatment of rectal cancer. It is known to reduce the rate of local recurrences. However, the influence on long-term survival is unclear.
- Trial name
- NCT00910143
- Testing
- conventional rectal surgery, total mesorectal excision
- Where
- Switzerland
- Volunteers
- 194 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Esophageal Cancer, Gastric Cancer (Diagnosis)
Exercise Training After Upper Gastrointestinal Cancer Surgery
This randomized controlled trial aims to determine the optimal exercise intensity for improving postoperative recovery in patients with upper gastrointestinal cancer.
- Conditions
- Esophageal Cancer, Gastric Cancer (Diagnosis), Upper Gastrointestinal Cancer
- Trial name
- NCT07561840
- Testing
- High-Intensity Interval Training (HIIT), Low-Intensity Continuous Training (LICT)
- Where
- 2 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Kansai Medical University
Gastric Emptying, Preoperative Care
Incidence of Stomach Fullness and Associated Factors in Elective Surgical Patients
The aim of this prospective, observational study is to evaluate the incidence of residual gastric content in elective surgical patients who adhered to preoperative fasting guidelines and to investigate associated patient-related…
- Conditions
- Gastric Emptying, Preoperative Care, Preoperative Fasting, Elective Surgical Procedures
- Trial name
- NCT06606782
- Where
- Turkey (Türkiye)
- Volunteers
- 404 people
- Sponsor
- Recep Tayyip Erdogan University
Stage II Colon Cancer, Stage III Colon Cancer
Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery
Background: 1. . The incidence and mortality of colon cancer are high in China and in the world. 2. . The treatment of many patients in the real world is not standardized, and there are problems such as over-treatment or…
- Conditions
- Stage II Colon Cancer, Stage III Colon Cancer, Adjuvant Therapy
- Trial name
- NCT03958435
- Where
- 3 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer
Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving drugs in different ways may kill more tumor cells.
- Trial name
- NCT00002525
- Testing
- fluorouracil, leucovorin calcium
- Where
- United States
- Volunteers
- 859 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Colon Cancer, Inflammatory Bowel Diseases
Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine
Patients receiving perioperative intravenous lidocaine, post operative restoration of bowel movement will be faster and decrease pain intensity, opioid consumption and side effects, length of hospital stay; probably as a result…
- Conditions
- Colon Cancer, Inflammatory Bowel Diseases, Diverticulitis
- Trial name
- NCT01155440
- Testing
- Lidocaine, Thoracic epidural block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Crohn's Disease, Ulcerative Colitis
Disease Course in an IBD Cohort in the Era of Biological Treatment
The aim of the study is to do a 7-year follow-up of a consecutive inception cohort of 562 adults and children diagnosed and registered with inflammatory bowel disease in 2003-04 in order to evaluate the consequences of biological…
- Trial name
- NCT01468090
- Where
- 2 sites in Denmark
- Volunteers
- 192 people
- Sponsor
- Hvidovre University Hospital
Postoperative Nausea and Vomiting
A Machine Learning Prediction Model for Delayed CIPONV
Postoperative nausea and vomiting (PONV) can lead to serious postoperative complications, but most symptoms are mild. Clinically important PONV (CIPONV) refers to PONV symptoms that have a significant impact on the patient's…
- Trial name
- NCT06443697
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,154 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Esophageal Cancer, Metastatic Disease
The Role of Surgery for Esophageal Cancer With Metastatic Disease (M1)
Treatment of stage IV esophageal cancer is traditionally palliative, but treatment response is usually poor. The role of surgery in the treatment of advanced esophageal cancer remains controversial.
- Trial name
- NCT06424210
- Where
- Taiwan
- Volunteers
- 163 people
- Sponsor
- National Taiwan University Hospital
Congenital Esophageal Atresia
Robotic Versus Thoracoscopy Versus Thoracotomy Repair for Congenital Esophageal Atresia
Thoracotomy repair has long been considered the gold standard for the repair of esophageal atresia but is associated with potential musculoskeletal complications which may result in long term morbidity for the patient.
- Trial name
- RR VS TR VS OR (NCT06208449)
- Testing
- Robotic repair for EA, Thoracoscopic repair for EA, Thoracotomy repair for EA
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zunyi Medical College
Probiotics, Infant, Newborn
Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery
Congenital defects of the gastrointestinal tract commonly require surgical intervention in the neonatal period. Intestinal surgery during this critical period of microbiome acquisition results in aberrant colonization of the…
- Conditions
- Probiotics, Infant, Newborn, Surgical Procedures, Operative, Gastro-Intestinal Disorder
- Trial name
- ProPS (NCT03266315)
- Testing
- FloraBaby
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Calgary
Intestinal Obstruction, Digestive System Surgical Procedures
Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery
The purpose of the study is to evaluate the efficacy of Seprafilm in reducing the incidence of bowel obstruction and to evaluate the incidence of all serious adverse events (SAEs) associated with the use of Seprafilm occurring…
- Trial name
- NCT00130715
- Testing
- Seprafilm Bioresorbable Membrane
- Where
- 21 sites in United States, Canada and 3 more
- Sponsor
- Genzyme, a Sanofi Company
Hirschsprung Disease
Registry for Hirschsprung Disease of the BELAPS
Registry for Hirschsprung disease of the BELAPS (Belgian Association of Pediatric Surgery) Protocol Short Title/Acronym / Sponsor name BELAPS Principal Investigator Prof. Dr.
- Trial name
- NCT04622410
- Where
- Belgium
- Volunteers
- 432 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Cancer, Quality of Life
Follow-up After Surgery for Colorectal Cancer
The currently developed implementation study aims to evaluate if a patient-led home-based follow-up approach is successful, improves quality of life, reduces anxiety and lessens fear of cancer recurrence during the years after…
- Trial name
- FUTURE-primary (NCT05656326)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Esophageal Cancer
Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00470184
- Testing
- capecitabine, oxaliplatin, gene expression analysis
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Roswell Park Cancer Institute
Colorectal Cancer, Nutrition Related Cancer
Nutritional Risk Factors and Colorectal Surgery
This observational study aims to learn about the relationship between the nutritional status of patients with colorectal cancer and clinical outcome after colorectal surgery.
- Trial name
- NCT05957744
- Testing
- Colorectal surgery
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- University Clinic Dr Dragisa Misovic-Dedinje