Clinical trials: Gambling Disorder
Pathological Gambling
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling
After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day at visit 6 unless clinical improvement has…
- Trial name
- NCT00273702
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pathological Gambling
Dopamine Responsivity in Gamblers
This study deals with how people decide between rewards of different value. The investigators want to understand how the brain's dopamine system impacts this kind of decision making.
- Trial name
- NCT02772978
- Testing
- Tolcapone
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Child, Only, Chronic Renal Failure in Children
The Effect of a Mobile Game Application on Children With CRF
The aim of this study was to investigate the effect of a mobile game application developed for children with Chronic Renal Failure (CRF) on disease management. The study was a randomized controlled trial.
- Conditions
- Child, Only, Chronic Renal Failure in Children, Gambling, Disease
- Trial name
- NCT07162220
- Testing
- The clinic's routine education program, Mobile game app
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Akdeniz University
Gambling, Pathological
Adding Contingency Management to Treatment as Usual for Disordered Gambling.
The aim of this study is to conduct a trial to investigate the efficacy of adding Contingency Management (CM) to Treatment as Usual (TAU) for the treatment of Disordered Gambling.
- Trial name
- NCT02613754
- Testing
- Contingency Management, Treatment as Usual
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Gambling, Pathological Gambling
Indicated Prevention With At-Risk Gamblers
The overall purpose of this study is to reduce the prevalence of gambling risk in college students by evaluating the effectiveness of different treatments in reducing gambling behavior and related negative consequences.
- Conditions
- Gambling, Pathological Gambling, Problem Gambling
- Trial name
- NCT00078273
- Testing
- Personalized Feedback Intervention, Cognitive Behavioral Intervention
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Washington
Gambling Disorder
Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial
The investigators assume that High-intensity transcranial Alternating Current Stimulation (HI-tACS) could improve gambling disorder patients' executive-control function by modulating abnormal neural activity, particularly…
- Trial name
- HITACSRCT-GD (NCT07228182)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Substance Use Disorder
OPAL: "Opiates and PhArmacoLogy"
The aim of this study is to determine the current prevalence of co-addictions, including problem/pathological gambling, in patients receiving Opiate Substitution Treatment (OST), and to then compare patients receiving OST with or…
- Trial name
- OPAL (NCT01847729)
- Where
- 7 sites in France
- Volunteers
- 263 people
- Sponsor
- Nantes University Hospital
Parkinson Disease
Influence of Emotions on Decision-making in Parkinson's Disease
Parkinson's disease mainly affects the dopaminergic neurons of the Substancia nigra, which project on the striatum. Neuronal death within this structure leads to a decrease in dopamine levels.
- Trial name
- NCT03342339
- Testing
- cognitive examination, viewing of video, Iowa Gambling Task
- Where
- 2 sites in France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Addictive Behaviors, Internet Addiction Disorder
Is Craving a Central Criterion for Diagnosing a Behavioral Addiction?
This study is a cross-sectional observational study designed to evaluate the diagnostic criteria for behavioral addictions (gambling, online video game disorder, screen addiction, food addiction, and pathological use of sex…
- Conditions
- Addictive Behaviors, Internet Addiction Disorder, Gambling, Technology Addiction
- Trial name
- CRIBA (NCT07854912)
- Testing
- Questionnaires, Telephone interview
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Gambling
Drug Treatment for Pathologic Gambling Disorder
This study will establish the best dose of the drug naltrexone to treat patients with Pathological Gambling Disorder (PGD) and severe urge symptoms.
- Trial name
- NCT00053677
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Transcutaneous Electric Nerve Stimulation, Gambling
Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder
The investigators assume that transcranial Alternating Current Stimulation (tACS) could improve gambling disorder patients' executive-control function by adjusting the synchronization patterns and enhancing the functional…
- Trial name
- NCT06195995
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Mental Health Center
Gambling Disorder
Don't Go There: A Geospatial mHealth App for Gambling Disorder
The goal of this project is to develop and to test the efficacy of a novel mHealth app for gambling disorder. The app capitalizes on smartphones' global positioning software (GPS) that recognizes a user's location to within 15…
- Trial name
- NCT04158037
- Testing
- mHealth App
- Where
- United States
- Sponsor
- St. Louis University
Pathological Gambling
Repeated Low-frequency Transcranial Magnetic Stimulation Reduces Cue-induced Craving: a Randomized, Prospective, Double-blind, Sham-controlled, Cross-over Study
The aim of this study is to evaluate the effect of repeated low-frequency Transcranial Magnetic Stimulation (rTMS) of the right dorsolateral prefrontal cortex, combined with gambling cues, on gambling craving.
- Trial name
- STIMJEU (NCT01560351)
- Testing
- rTMS
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Nantes University Hospital
Pathological or "at Risk" Gambling
Transversal Multiaxial Evaluation and 5-year Follow-up of a Cohort of French Gamblers (JEU)
This study is divided into two stages. The first stage is a transversal study and corresponds to the recruitment of participants, which will last about two years.
- Trial name
- NCT01207674
- Testing
- Summons of patients and filling questionnaire
- Where
- 7 sites in France
- Volunteers
- 641 people
- Sponsor
- Nantes University Hospital
Gambling Disorder
Theta Burst Stimulation for Gambling Disorder
The goal of this clinical trial is to investigate the efficacy of theta burst stimulation in individuals with gambling disorder.
- Trial name
- NCT05872750
- Testing
- theta burst stimulation
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- Taipei City Hospital
Gambling Disorder, Substance Use Disorders
Integrative Couple Treatment for Gambling/Substance Use Disorder
The aim of the study is to compare couple-based treatment to individual treatment (treatment as usual) for addiction (gambling or substance use disorder).
- Trial name
- NCT05833503
- Testing
- Integrative Couple Treatment for Addiction (ICT-A), Treatment individual as usually offered
- Where
- 7 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Université du Québec à Trois-Rivières
Pathological Gambling
Investigation of Naltrexone for Pathological Gambling
The investigators plan to investigate the safety, tolerability, and efficacy of the opioid antagonist naltrexone in Pathological Gambling.
- Trial name
- NCT01057862
- Testing
- Naltrexone
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Pathological Gambling
Topiramate Trial for Pathological Gamblers
Objectives: Pathological gambling (PG) is a prevalent disorder with no approved pharmacological treatment. Previous reports suggest that topiramate could be useful in reducing impulsivity in PG, and craving in other addictions.
- Trial name
- NCT01843699
- Testing
- Topiramate flexible dosage, 4-session gambling cognitive restructuring
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo
Marijuana Use Disorder
Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks
The purpose of this study is to investigate the effects of smoked marijuana on both risk taking and decision making tasks.
- Trial name
- NCT00373399
- Testing
- Inactive Marijuana (0% THC), Low THC marijuana (1.8 %THC), High THC marijuana (3.9% THC)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Gambling Disorder
Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder
The purpose of this research is to investigate the effect of transcranial temporal interference stimulation (tTIS) targeting the dorsal anterior cingulate cortex in patients with gambling disorder.
- Trial name
- NCT06467422
- Testing
- tTIS on dACC, theta frequency (5 Hz), tTIS on dACC, High frequency
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center