Clinical trials: Gall Stones
Common Bile Duct Stone
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Common bile duct (CBD) stones are a frequent condition that can lead to severe complications if not treated. The standard approach involves endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone…
- Trial name
- NCT07030829
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Common Bile Duct Gall Stones, Common Bile Duct GallStones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS.
- Trial name
- NCT02329977
- Testing
- standard barium meal examination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Air Force Military Medical University, China
Common Bile Duct Calculi
Application and Translational Research of 3D Printed in Treatment of Choledocholithiasis Under ERCP
The goal of this clinical trial is to learn about Application and translational research of 3D printed models in the surgical treatment of common bile duct stones under endoscopic retrograde cholangiopancreatography.
- Trial name
- NCT06071247
- Testing
- 3D printed models
- Volunteers
- 60 people
- Sponsor
- Jiawei Qin
Cholecystitis; Gallstone
Intraoperative Spillage of Bile and Gallstones During Laparoscopic Cholecysetectomy
1. determine the most important factors which is responsible for the outcome post bile and gallstones spillage during laparoscopic cholecystectomy 2. the management of complications of bile and gallstones spillage
- Trial name
- NCT04041726
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pancreatic Cancer, Cholangiocarcinoma
MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers
pancreatic or biliary-tract cancer can be a serious diagnosis, as many patients present too late for surgery. Cancer cells have been found to release small messenger molecules called that regulate cancer genes called microRNAs…
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma, Ampullary Cancer, Biliary Stricture
- Trial name
- MIRABILE (NCT06258824)
- Testing
- Small RNA Sequencing and Validation of candidate miRNAs
- Where
- United Kingdom
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Biliary Tract Diseases, Gallbladder Diseases
Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease
The trial compares minilaparotomy (small-incision) cholecystectomy with (key-hole) laparoscopic cholecystectomy by randomly allocating patients with gallbladder disease to two groups of surgeons, each group being trained for one…
- Conditions
- Biliary Tract Diseases, Gallbladder Diseases, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT00370344
- Testing
- Laparoscopic cholecystectomy, Small-incision open cholecystectomy
- Where
- 2 sites in Sweden
- Volunteers
- 355 people
- Sponsor
- Umeå University
Cholecystitis, Gallstones
3D Versus 4K Laparoscopic Cholecystectomy
Introduction: Three-dimensional key-hole surgery ('laparoscopic') systems are proven to reduce the time required to complete tasks in laboratory settings.
- Trial name
- NCT02858986
- Testing
- 3D laparoscopy, 4K laparoscopy
- Volunteers
- 120 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Cholecystitis; Gallstone, Cholecystolithiasis
Effect of TENS on Patient Outcomes After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of TENS (Transcutaneous Electrical Nerve Stimulation) on patient outcomes after laparoscopic cholecystectomy.
- Trial name
- TENS (NCT05962853)
- Testing
- Experimental group (Transcutaneous Electrical Nerve Stimulation)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Gallstone Disease, Bariatric Surgery
ABCG8, UGT1A1 and Gallstone Disease After Bariatric Surgery
The goal of this observational genetic case-control study is to learn whether two specific genetic variants in ABCG8 and UGT1A1 are associated with gallstone disease after bariatric surgery.
- Conditions
- Gallstone Disease, Bariatric Surgery, Metabolic Surgery, Cholecystectomy
- Trial name
- NCT07702630
- Testing
- blood sampling
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Choledocholithiasis, Choledocholithiasis With Cholecystitis
The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis.
A prospective randomized trial. It is planned to analyze groups of patients with cholecystitis and choledocholithiasis. As part of the study, after signing the consent, the patients will be divided into two groups that have…
- Trial name
- DILAILA (NCT07503964)
- Testing
- Endoscopic retrograde cholangiopancreatography with papillotomy and stone evacuation from common bile duct., Laparoscopic Cholecystectomy., Laparoscopic transcystic balloon dilatation of the papilla Vateri.
- Where
- Latvia
- Volunteers
- 100 people
- Sponsor
- Riga East Clinical University Hospital
Gallstones
Laparoscopic Cholecystectomy With Retro-infundibular Approach
Aimed to evaluate laparoscopic cholecystectomy by retro-infundibular (RI) approach compared to standard laparoscopic cholecystectomy (SLC) in difficult cases with scarred chole-cystohepatic (Calot's) triangle.
- Trial name
- NCT02947256
- Testing
- standard laparoscopic cholecystectomy, RI approach
- Where
- 2 sites in Egypt
- Volunteers
- 125 people
- Sponsor
- Minia University
Cholecystolithiasis
UDCA for Symptomatic Gallstone Disease
We conduct a randomized, double-blind, placebo-controlled trial on effects of UDCA on biliary pain and complications in highly symptomatic gallstone patients scheduled for cholecystectomy.
- Trial name
- NCT00161083
- Testing
- ursodeoxycholic acid
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- UMC Utrecht
Laparoscopic Cholecystectomy
Effectiveness and Safety of LED Light Source System for Endoscope
This trial is designed as a prospective, multi-center, single-blind, parallel, randomized controlled clinical trial. The trial will be carried out in 5 centers, involving 220 subjects as estimated who will be divided into the…
- Trial name
- ENV (NCT04561583)
- Testing
- LED light source system for endoscope, Pinpoint Endoscopic Fluorescence Imaging System
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics
Cholecystitis, Acute, Cholecystitis; Gallstone
Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy
The study will compare the outcomes of patients with gallstone related cholecystitis who are poor surgical candidates undergoing EUS guided cholecystoenterostomy via a lumen apposing metal stent (LAMS).
- Trial name
- NCT04167072
- Testing
- Stent removal
- Where
- United States
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Gallstone Disease
Radiological Investigation of Bile Duct Obstruction
Patients with gallstone disease should be checked whether a common bile duct (CBD) stone could be present. In case of a certain suspicion for CBD stones further investigations should be performed.
- Trial name
- RIBO (NCT02351492)
- Testing
- Cholecystectomy and intraoperative cholangiography, Magnet resonance cholangio-pancreaticography, magnet resonance imaging
- Where
- Switzerland
- Volunteers
- 122 people
- Sponsor
- University Hospital, Basel, Switzerland
Gallbladder Malignant Neoplasm
Validation of the Association Between the Abundance of Three Bacterial Genera in Stool Samples and the Risk of Gallbladder Cancer in South American Patients With Gallstones
In our previous work, we found three types of bacteria in stool samples from South American patients with gallstones linked to a higher risk of gallbladder cancer.
- Trial name
- NCT07635745
- Where
- 4 sites in Bolivia, Chile and 2 more
- Volunteers
- 120 people
- Sponsor
- Centre Paul Strauss
Cholelithiasis Associated With Common Bile Duct Stones
Optimal Timings of Laparoscopic Cholecystectomy After ERCP in Patients With Gallstones Along With CBD Stones
This randomized controlled trial aims to compare the mean operative time and outcomes of early versus delayed laparoscopic cholecystectomy after ERCP in patients with cholelithiasis and choledocholithiasis.
- Trial name
- ED-LC (NCT07517627)
- Testing
- Early laparoscopic cholecystectomy, Delayed Laparoscopic cholecystectomy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Rija Zainab
Biliary Obstruction
Laparoscopy-Assisted Transgastric ERCP
We describe a case of a 57-year-old patient with altered RYGB anatomy, who underwent a laparoscopic cholecystectomy with a intra-operative cholangiogram showing a stone on the common bile duct.
- Trial name
- NCT03925766
- Where
- Mexico
- Volunteers
- 1 people
- Sponsor
- Tecnologico de Monterrey
Gall Stones (& [Calculus - Gall Bladder]), Surgery
Major Surgery as a Risk of Gall Stone Disease?
Gall stone disease is one of the most common diseases occurring in the world as well as in our country, Nepal. This disease is problematic to a lot of patients and poses a huge economic burden to the country.
- Trial name
- NCT04675190
- Testing
- Major abdominal Surgery
- Where
- 3 sites in Nepal
- Volunteers
- 755 people, healthy volunteers welcome
- Sponsor
- Nepal Medical College and Teaching Hospital