Clinical trials: Gabapentin
Alcohol Withdrawal Syndrome
Gabapentin for Alcohol Withdrawal Syndrome
The current "gold-standard" for the management of alcohol withdrawal syndrome (AWS) is symptom-triggered administration of benzodiazepines.
- Trial name
- NCT03012815
- Testing
- Gabapentin, Benzodiazepines, Divalproex Sodium
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Pain, Postoperative, Acute Pain
Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures
The purpose of this study is to assess the effectiveness of pre-operative administration of gabapentin 900 mg in management of acute post-operative pain in patients undergoing oral and maxillofacial surgical procedures.
- Conditions
- Pain, Postoperative, Acute Pain, Facial Pain
- Trial name
- NCT02957097
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder
Emergency Department-Initiated Medications for Alcohol Use Disorder
The proposed study will be the first randomized clinical trial to evaluate a comprehensive Emergency Department (ED)-based intervention for moderate to severe Alcohol Use Disorder (AUD) combining Screening, Brief Intervention and…
- Trial name
- NCT05827159
- Testing
- Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Yale University
Alcohol Dependence
Treatment for Alcohol Dependence With Gabapentin
Alcohol use disorders are present across medical specialties, with alcohol-related deaths particularly prevalent in the categories of injury, liver cirrhosis, cancer, cardiovascular disease, disorders of the peripheral nerves and…
- Trial name
- TAG (NCT02771925)
- Testing
- Gabapentin 2g/day divided in two doses for 24 weeks
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dayanand Medical College and Hospital
Healthy
A Relative Bioavailability Study of Gabapentin Tablets 800 mg Under Non-fasting Conditions
The purpose of this study is to compare the relative bioavailability of 800 mg Gabapentin Tablets by Purepac Pharmaceutical Co. with that of 800 mg NEURONTIN® Tablets by Parke-Davis following a single oral dose (1 x 800 mg) in…
- Trial name
- NCT00865059
- Testing
- Gabapentin 800 mg Tablets, single dose, NEURONTIN® 800 mg Tablets, single dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Pain, Postoperative
Use of Preoperative Gabapentin in Patients Undergoing Laparoscopic Cholecystectomy
The multimodal analgesia involves the administration of two or more analgesic agents that exert their effects via different analgesic mechanisms, providing superior analgesia with fewer side effects.
- Trial name
- NCT03583892
- Testing
- Gabapentin
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar do Porto
Cocaine-Related Disorders
Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7
The purpose of this CREST (Clinical Rapid Evaluation Screening Trial) study is the treatment of cocaine dependence using reserpine, gabapentin, or lamotrigine vs. an unmatched placebo control.
- Trial name
- NCT00015106
- Testing
- Lamotrigine
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Neuropathic Pain, Multiple Sclerosis
Efficacy and Safety Evaluation of Nabilone as Adjunctive Therapy to Gabapentin for the Management of Neuropathic Pain in Multiple Sclerosis
The purpose of this study is to determine whether nabilone (Cesamet) when used as an adjunctive agent with gabapentin (Neurontin) provides significantly improved pain relief over gabapentin alone for the management of neuropathic…
- Trial name
- NCT00480181
- Testing
- nabilone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
RLS
A PK and Safety Evaluation of HORIZANT (Gabapentin Enacarbil) in Adolescents With Moderate-to-Severe Primary RLS
The primary objective is to assess the pharmacokinetics (PK) of gabapentin following the single-dose administration of HORIZANT (Gabapentin Enacarbil) in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe…
- Trial name
- RLS (NCT02633657)
- Testing
- HORIZANT 300 mg
- Where
- 4 sites in United States
- Sponsor
- XenoPort, Inc.
Healthy
Bioequivalence Study of Gabapentin 400 mg Capsules Under Fasting Conditions
The objective of this study was to compare the single-dose relative bioavailability of Ranbaxy and Parke-Davis (Neurontin®) 400 mg Gabapentin, following administration of a 400 mg dose under fasting conditions
- Trial name
- NCT00778271
- Testing
- Gabapentin 400mg capsules
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Breast Cancer, Hot Flashes
Gabapentin With or Without Antidepressants in Treating Hot Flashes in Women Who Have Had Breast Cancer or Have Concerns About Taking Hormone Therapy
RATIONALE: Gabapentin may be effective in relieving hot flashes in women who have had breast cancer or who have concerns about taking hormone therapy to treat hot flashes.
- Trial name
- NCT00087399
- Testing
- gabapentin, antidepressant
- Where
- 162 sites in United States
- Volunteers
- 118 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hand Injuries
Analgesic Effects of Gabapentin and Paracetamol
This research is about the effects of drug gabapentin; which is an amino acid that is structurally similar to neurotransmitter GABA.
- Trial name
- GABA (NCT04068506)
- Testing
- Gabapentin 600 mg Tab
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Dow University of Health Sciences
Abuse Potential
Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users
This will be a randomized, double-blind, double-dummy, placebo- and active-controlled, 6 treatment, 6-period crossover single-dose, Williams square design study in healthy male and/or female adult, non-drug-dependent recreational…
- Trial name
- NCT05319756
- Testing
- gabapentin 600 mg, gabapentin 1200 mg, gabapentin 600 mg and oxycodone HCl 20 mg
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Viatris Specialty LLC
Hyperalgesia, Opioid-Related Disorders
Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia
Individuals who reduce or stop use of opioid medications are at risk for developing hyperalgesia, which is an increased sensitivity to pain.
- Trial name
- NCT00218374
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pain
The Effectiveness of Gabapentin for Post-operative Pain Following Cesarean Section
Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of operations.
- Trial name
- NCT01094925
- Testing
- lactose, Gabapentin 300mg, Gabapentin 600mg
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Cholecystitis, Chronic
Comparison Between Oral Gabapentin Versus Diclofenac Sodium in Post-operative Analgesia Laparoscopic Cholecystectomy
this study amis to compare between perioperative oral Gabapentin versus Diclofenac sodium on postoperative analgesia patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT07131527
- Testing
- Gabapentin, Diclofenac Sodium
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Chronic Pain
Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic Pain
The objective of the study is to evaluate the efficacy of gabapentin as adjunctive therapy to morphine in the treatment of severe chronic neuropathic or mixed pain in children from 3 months to less than 18 years of age assessed…
- Trial name
- GABA-2 (NCT03275012)
- Testing
- Gabapentin + Morphine
- Sponsor
- Pharmaceutical Research Management srl
Painful Diabetic Neuropathy
Trazodone in Painful Diabetic Neuropathy
The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep…
- Trial name
- NCT03202979
- Testing
- Trazodone 20 mg, Trazodone 10 mg
- Where
- 20 sites in Czechia, Hungary and 1 more
- Volunteers
- 142 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Pain
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Opioids are effective analgesics, but cause side effects including sedation, respiratory depression, low blood pressure, nausea, and constipation.
- Trial name
- NCT02840240
- Testing
- Gabapentin enacarbil
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The Cleveland Clinic
Cerebral Tumor
The Effects of Gabapentin Premedication on Neurosurgery
The study is to observe the effects of gabapentin premedication on postoperative pain,vomiting and nausea in patients undergoing neurosurgery. 100 neurosurgical patients are randomized into groups gabapentin(GG) or placebo(GP).
- Trial name
- NCT02306278
- Testing
- gabapentin, vitamin capsules
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Capital Medical University