Clinical trials: GDM
Gestational Diabetes, Continuous Glucose Monitoring
The Effect of Continuous Glucose Monitoring on Glycemic Control and Pregnancy Outcomes in Gestational Diabetes Mellitus
The purpose of this study is to determine if Continuous glucose monitoring improves glycemic control and pregnancy outcomes of Gestational Diabetes Mellitus
- Trial name
- NCT03955107
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Gestational Diabetes, Pregestational Diabetes
Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes
Pregestational diabetes (PGD) during pregnancy may be associated with an increased rate of spontaneous abortions, intrauterine death and congenital anomalies among the offspring.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, IDM (Infant of Diabetic Mothers), Neurodevelopmental Outcome
- Trial name
- NCT01255384
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Gestational Diabetes Mellitus in Pregnancy, Hyperprolactinemia Pregnancy
Prolactin and FGF21 in Gestational Diabetes Mellitus
Prolactin (PRL) and PRL receptor (PRLR) signaling has been validated to play an important role in the modulation of glucolipid metabolism.
- Trial name
- NCT05528393
- Testing
- Blood sampling
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shen Qu
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Gestational Diabetes, Pregnancy Related
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes
The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM).
- Trial name
- START 1 (NCT06419777)
- Testing
- Insulin
- Where
- 2 sites in United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Gestational Diabetes, Eye Diseases
Fundus Findings and Thiol-Disulfide Homeostais
Gestational diabetes mellitus is associated with abnormal blood sugar levels throughout pregnancy in women without prior diabetes. Many studies have been conducted on the relationship between diabetes and oxidative stress.
- Conditions
- Gestational Diabetes, Eye Diseases, Retinal Disease, Oxidative Stress
- Trial name
- NCT05958927
- Testing
- tear test and eye measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suzan Dogruya
Gestational Diabetes, Pre-Eclampsia
Body Fat Index for Obstetric Risk Stratification
Primary Outcome:- GDM Diagnosis Secondary Outcomes:- Pre-eclampsia diagnosis. Cesarean section delivery due to labor dystocia defined as protracted or arrested progress of labor using labor partogram.
- Conditions
- Gestational Diabetes, Pre-Eclampsia, Labour Dystocia
- Trial name
- BFIors (NCT05533996)
- Testing
- ultrasound
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Assiut University
GDM, Preterm Preeclampsia
Advancing Stillbirth Prevention Through Innovative Risk Evaluation (ASPIRE) Clinical Study
ASPIRE will be a multi-site, prospective, two-part longitudinal, noninterventional observational cohort study of nulliparous singleton pregnant women to evaluate biomarkers from blood and ocular imaging for prediction of…
- Conditions
- GDM, Preterm Preeclampsia, Preeclampsia, Fetal Growth Restriction (FGR)
- Trial name
- ASPIRE (NCT07669935)
- Testing
- None (this is an observational study with no intervention)
- Where
- 2 sites in United States
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Medicines360
Dietary Modification, Weight Loss
Feasibility of a Postpartum Lifestyle Intervention on the Cardiometabolic Risk Profile of GDM Women
The goal of the study is to investigate the effect of a lifestyle intervention program (adoption of exclusive breastfeeding, healthy diet and regular physical activity) on minimizing postpartum weight retention among women with…
- Conditions
- Dietary Modification, Weight Loss, Physical Activity, Breastfeeding
- Trial name
- DEPART (NCT02872402)
- Testing
- Lifestyle intervention, Active control lifestyle intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Gestational Diabetes Mellitus
The Early Diagnosis of Gestational Diabetes Mellitus Study
The main purpose of the study is to evaluate an OGTT at 18 to 20 gestational weeks as an early diagnosis method of GDM in low risk pregnant women.
- Trial name
- EDoGDM (NCT02740283)
- Testing
- glycemic monitoring, dietary guide
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Gestational Diabetes Mellitus
Intrapartum Glucose Management Among Women With Gestational Diabetes Mellitus
Gestational Diabetes Mellitus (GDM) is one of the most common medical complications of pregnancy. Neonatal hypoglycemia is a common and well described complication for infants born to mothers with GDM and diabetes mellitus (DM)…
- Trial name
- NCT02596932
- Testing
- Standard Protocol for intrapartum glucose management, Experimental Protocol for intrapartum glucose management
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Diabetes, Gestational
Gestational Diabetes Mellitus Trial (GDM)
Gestational diabetes mellitus (GDM) is a type of diabetes (high blood sugar) that occurs in pregnant women. This study will determine whether treating pregnant women who have mild GDM improves the health of their babies.
- Trial name
- GDM (NCT00069576)
- Testing
- nutritional counseling, self blood glucose monitoring
- Where
- 16 sites in United States
- Volunteers
- 7,381 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
GDM
Effect of Early Lifestyle Intervention on Perinatal Outcomes in High-risk Women for Gestational Hyperglycemia
This study aims to explore whether early intervention for high-risk groups of gestational hyperglycemia can improve insulin resistance and effectively prevent the occurrence of GDM, and evaluate which pathophysiological subtypes…
- Trial name
- NCT07141173
- Testing
- Individual lifestyle management
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics
Gestational Diabetes
Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes
Obese women with history of gestational diabetes are in great danger to develop type 2 diabetes (T2D) within 5-10 years after delivery.
- Trial name
- Liragest (NCT04324229)
- Testing
- Liraglutide 6 MG/ML [Victoza]
- Where
- Finland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Gestational Diabetes
The Role of Umbilical Cord Thickness in Prediction of Fetal Macrosomia in Patients With Gestational Diabetes Mellitus
The aim of this work is the prediction of fetal macrosomia by measuring: 1. HbA1C. 2. Umbilical cord thickness. 3. Interventricular septum thickness.
- Trial name
- NCT02643225
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Maternal Behavior, Mobile Health
A Prospective Randomized Controlled Trial of Mobile Medical Used for Management of Pregnant Women
A multicenter, randomized controlled trial was conducted to investigate whether health education and life style management through WeChat group chat was: 1. more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Maternal Behavior, Mobile Health, Pregnancy Outcome, GDM
- Trial name
- NCT03748576
- Testing
- telemedicine: management through WeChat group chat
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Gestational Diabetes, Oxidative Stress
Prevention of Maternal and Fetal Metabolic Complications With Diet and Nutraceutical Supplementation in Pregnant Women Affected by Gestational Diabetes: a Randomized, Double-blind Placebo Controlled Trial.
Our trial aims to assess the effect of nutraceutical supplements (omega-3 fatty acids, anthocyanins and alpha-cyclodextrins) in patients affected by gestational diabetes.
- Trial name
- PREDIP2 (NCT05393843)
- Testing
- omega-3 fatty acids, anthocyanins and alpha-cyclodextrins, diet
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Mobile Health Apps, Lifestyle Intervention
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
The goal of this pragmatic randomized controlled trial is to evaluate the effectiveness of an AI-enabled mobile health management application ("Better Pregnancy" app), grounded in the Theory of Planned Behavior, in preventing…
- Conditions
- Mobile Health Apps, Lifestyle Intervention, Prevention, Multi-component Based Behavioral Intervention
- Trial name
- NCT07582068
- Testing
- Multi-component lifestyle intervention
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao