Clinical trials: Functional Voice Disorder
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Respiratory Function, Vocal Performance
Combined SOVT and Respiratory Exercises: Effects on MPT and Respiratory Function
This study aims to investigate the effects of combined SOVT and breathing exercises, administered twice weekly for six weeks to conservatory students, through a randomized controlled trial.
- Conditions
- Respiratory Function, Vocal Performance, Voice
- Trial name
- NCT07677501
- Testing
- combined soft and breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance
Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults
The autonomic nervous system consists of two branches, the sympathetic and the parasympathetic, which must work in balance. Its functioning can be measured indirectly by heart rate variability, which is the time between…
- Conditions
- Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance, Transcutaneous Vagus Nerve Stimulation
- Trial name
- tVNS_older (NCT07292623)
- Testing
- Active location tVNS
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Spasmodic Dysphonia, Voice Tremor
Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor
Using a comprehensive approach of clinico-behavioral testing, neuroimaging and pharmacogenetics, the researchers will examine the clinical effects of sodium oxybate and the matched placebo on voice symptoms in spasmodic dysphonia…
- Trial name
- NCT03292458
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Kristina Simonyan
Functional Independence, Respiratory Insufficiency
More Air - Better Performance - Faster Recovery
The objective of this study is to investigate i) the effect of 3 weeks IMT to adults post-stroke to maximal inspiratory pressure (MIP) and ii) the effects of 3 weeks IMT to the degree of dependency in activities of daily living…
- Trial name
- IMT (NCT04686019)
- Testing
- Inspiratory muscle training (IMT)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Central Jutland Regional Hospital
Gastroesophageal Reflux, Functional Dysphonia
Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome
Overlapping gastrointestinal symptoms of functional gastrointestinal diseases (FGIDs) is an internationally recognized problem in modern medical diagnosis and treatment.
- Trial name
- NCT05312463
- Testing
- Tongjiang granule, Tongjiang granule simulant
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Secondary Hyperparathyroidism Due to Renal Causes
Pulmonary Function, Voice and Swallowing Symptoms After Parathyroidectomy
In this study, investigators measure patient's voice frequency, swallowing function, and O2 desaturation of the 6 mins walking test before surgery and 4 months after surgery, to find the increase of voice frequency, and…
- Trial name
- NCT04267965
- Testing
- parathyroidectomy plus bilateral thymectomy and autotransplantation
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Goiter
Goitres Influence on Voice Function - The Impact of Surgery
The aim of the study is to investigate the influence benign non-toxic goitre and the surgical treatment hereof on the voice function before and 6 months following surgery.
- Trial name
- SOLOIST (NCT02468921)
- Testing
- Thyroidectomy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Post-Thyroidectomy Dysphonia
Effects of Therapeutic Exercise With and Without Nerve Stimulation on Dysphonia in Post Thyroidectomy Patients
This clinical trial evaluates rehabilitation strategies for post-thyroidectomy dysphonia. Voice impairment is a frequent complication following thyroid surgery. It often occurs even without direct laryngeal nerve transection.
- Trial name
- NCT07811154
- Testing
- therapeutic exercise, therapeutic exercise + transcutaneous nerve stimulation
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Functional Dysphonia
A Trial of Transcranial Magnetic Stimulation in the Treatment of Functional Dyspepsia
The goal of this clinical trial is to learn if theta burst stimulation (TBS), a form of Transcranial Magnetic Stimulation (TMS), can treat functional dyspepsia (FD) and compare its effectiveness against conventional drug…
- Trial name
- NCT06559748
- Testing
- transcranial magnetic thetaburst stimulation （TBS）
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Functional Dysphonia, Voice Disorders
Dysphonia, Distress, and Perceived Control: Technology Based Assessment and Intervention
The purpose of this study is to pilot test a version of the intervention that has been tailored for participants with dysphonia.
- Conditions
- Functional Dysphonia, Voice Disorders, Dysphonia
- Trial name
- NCT03576365
- Testing
- VOICE Intervention Arm, Information-Only Arm
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Hoarseness, Dysphonia
A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC).
- Conditions
- Hoarseness, Dysphonia, Aphonia, Vocal Fold Scar
- Trial name
- NCT04290182
- Testing
- MSC-KI-PL-204
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska University Hospital
Vocal Folds
The Efficacy of Vocal Function Exercises for Laryngeal Cancers
The purpose of this study is to determine if the systematic practice of Vocal Function Exercises (VFE) improves selected measures of voice production in participants who have previously been irradiated for early glottic cancers…
- Trial name
- NCT02156518
- Testing
- Vocal Function Exercises, Vocal Hygiene
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Vrushali Angadi
Laryngeal Transplantation
Clinical Evaluation of Laryngeal Transplantation: Study of 3 Patients
The experience of face and hand composite tissue transplantations reported in the international community have mainly concerned trauma patients.
- Trial name
- ECLAT (NCT02821299)
- Testing
- Laryngeal transplantation
- Where
- 3 sites in France
- Volunteers
- 3 people
- Sponsor
- Hospices Civils de Lyon
Parkinson Disease
Speech and Voice Outcomes Following HD-tDCS Over the Left SMA
Pharmaceutical and neurosurgical treatments reliably ameliorate the cardinal motor symptoms in PD but, they often yield inconsistent outcomes for speech and voice disorders, with some studies showing exacerbation of pre-treatment…
- Trial name
- NCT06245070
- Testing
- Active transcranial direct current stimulation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Functional Voice Disorder, Psychogenic Voice Disorder
Autonomic Dysfunction in Functional Dysphonia
The first objective of this research project is to compare the occurrence and frequency of symptoms and/or disorders related to autonomic dysfunction in patients with functional dysphonia with gender- and age-matched vocally…
- Conditions
- Functional Voice Disorder, Psychogenic Voice Disorder, Muscle Tension Dysphonia
- Trial name
- NCT06100601
- Testing
- ANS regulation therapy, conventional voice therapy (CVT), ANS regulation therapy + CVT
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Functional Dysphonia
Speech Therapy and Functional Dysphonia After Thyroidectomy
Following a thyroidectomy, voice and swallowing alterations, which more frequently would appear to be caused by lesions of the laryngeal nerve, may occur.
- Trial name
- LSCC (NCT05963178)
- Testing
- Pre-operative counselling
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Laryngeal Dystonia, Focal Dystonia
Effects of Neuromodulation in Laryngeal Dystonia
Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life.
- Trial name
- NCT05095740
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Functional Dysphonia, Resonance Tube Voice Therapy
Management of Non-Organic Dysphonia in Adults.
The purpose of this study is to determine the effect of a semi-occluded vocal tract training program, "Resonant Tube Therapy," versus the "Traditional Smith-accent Method" on the quality of voice in patients with Non-Organic…
- Conditions
- Functional Dysphonia, Resonance Tube Voice Therapy, Smith Accent Method Therapy
- Trial name
- NCT06856785
- Testing
- Resonance Tube Voice Therapy in Water
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Traumatic Brain Injury, Stroke
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without…
- Conditions
- Traumatic Brain Injury, Stroke, Brain Disease, Movement Disorders (Incl Parkinsonism)
- Trial name
- NCT07056348
- Testing
- Deep Brain Stimulation (DBS) of the Motor Thalamus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jorge Gonzalez-Martinez