Clinical trials: Functional Dyspepsia
Dysbiosis
PPI and Microbiome in Healthy Volunteers and Functional Dyspepsia
Prospective interventional study of the effect of PPI on the duodenal microbiome in healthy volunteers and functional dyspepsia patients
- Trial name
- NCT03545243
- Testing
- Pantoprazole 40mg, PPI withdrawal
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia
The Effects of STW 5-II on Duodenal Mucosa and Symptoms in Functional Dyspepsia
The goal of this clinical trial is to find out whether a herbal medicine called STW 5-II can help improve gut health and symptoms in adults recently diagnosed with functional dyspepsia (FD)-a condition that causes frequent…
- Trial name
- DESTINY (NCT07198243)
- Testing
- STW 5-II
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Gastrointestinal Disorders, Overlap Syndromes
Overlap FGIDs and Genetic Polymorphism
1. To analyze the prevalence of overlap syndromes among NERD or RH, FD, and IBS patients, and to identify and to compare the differences in their characteristics and symptoms, and to determine their risk factors. 2.
- Trial name
- NCT04712617
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Functional Dyspepsia
Electrogastrogram (EGG) Reproducibility Study: EEG Readings in Normal Subjects and Dyspeptic Patients
The primary objective of this study is to determine whether EGG readings obtained from both normal subjects and dyspeptic patients are reproducible from one EGG recording to another on a different day.
- Trial name
- NCT00220883
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Temple University
Fabry Disease
Screening of Fabry Disease in Patients With GI Symptoms
Fabry disease screening study in patients diagnosed with gastrointestinal tract (GIT) disease, i.e. with the diagnosis of non-infectious inflammatory bowel disease, functional dyspepsia or irritable bowel syndrome in particular…
- Trial name
- GiFD (NCT04184986)
- Testing
- dry blood test
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- General University Hospital, Prague
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
VICO-trial: Video Consultations in the Follow-up of Children With Functional Abdominal Pain Disorders
The goal of this non-inferiority randomized controlled multi-center trial is to investigate the use of video consultations in the follow-up care of children aged 4 - 18 years old with functional abdominal pain disorders (FAPDs).
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Abdominal Migraine
- Trial name
- VICO (NCT06665867)
- Testing
- Video consultation, Face-to-face consultation
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Functional Dyspepsia
A Study to Demonstrate the Efficacy and Safety of Motilitone®
This is a phase IV , comparative study to evaluate the efficacy and safety of Motiltone® in treatment of the patients with functional dyspepsia.
- Trial name
- NCT01817465
- Testing
- Motilitone ®, Pantoline®, Motilitone® and Pantoline®
- Where
- South Korea
- Volunteers
- 389 people
- Sponsor
- Dong-A ST Co., Ltd.
Dyspepsia
Gastric Activity and Gastrointestinal Peptides in Patients With Functional Dyspepsia
Rome III criteria defined functional dyspepsia (FD) as the presence of symptoms from the gastroduodenal region in the absence of any organic, systemic or metabolic disease that is likely to explain the symptoms.
- Trial name
- DYSMOT-RIII (NCT02113527)
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Dyspepsia
Sourdough Bakery Products and Digestive Function
In a double-blind, randomised crossover study, two sourdough croissants (SC) or two brewer's yeast croissants (BC) were served to 17 (9 F; Age range 18-40; BMI range 18-24 kg/m2) healthy subjects to evaluate the effects of their…
- Trial name
- Digeribilità (NCT03207516)
- Testing
- Sourdough --> Brewer's Yeast, Brewer's Yeast --> Sourdough
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Irccs Sdn
Dyspepsia
Clinical Trial for 'Shen Qu Xiao Shi' Oral Liquid in the Treatments of Children's Functional Dyspepsia
With domperidone suspension as the control, the effect of shenqu xiaoshi oral liquid on functional dyspepsia in children was evaluated objectively through multi-center, randomized, double-blind and double-simulation experiment…
- Trial name
- NCT05030116
- Testing
- Shenqu Xiaoshi oral liquid, Domperidone suspension
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Ruijin Hospital
Dyspepsia
Functional Dyspepsia and Symptom Perception
Functional dyspepsia (FD) is a heterogeneous disorder with multifactorial pathophysiology. Patients with FD have visceral hypersensitivity to mechanical and chemical stimuli.
- Trial name
- NCT02522000
- Where
- 3 sites in Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Functional Dyspepsia
Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia
The study aims at evaluating physiological and patient-reported outcomes for a dual intervention approach including a stimulation device and support therapy in patients with functional dyspepsia.
- Trial name
- CONVERGE (NCT06360900)
- Testing
- Sensory device, Skills Building, Health Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spaulding Rehabilitation Hospital
Healthy Volunteers, Functional Dyspepsia
Comparing Pertechnetate SPECT/CT and Intragastric Pressure During Nutrient Drink for Gastric Accommodation
Functional dyspepsia (FD) is a common gastrointestinal disorder which can present with early satiety, postprandial fullness, epigastric pain and burning sensation in the absence of underlying disease.
- Trial name
- NCT06673719
- Testing
- 99mTc-pertechnetate SPECT/CT, Combined High-Resolution Manometry-Nutrient Drink Test
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Dyspepsia
Functional Dyspepsia - Effect of Acid-Reducing Treatment and Information.
Study title: Functional dyspepsia -- effect of acid reducing treatment and individualized information. Summary: 15-20% of all people experience dyspepsia each year.
- Trial name
- NCT00437346
- Testing
- Individualized and comprehensive information, Lanzo Melt
- Where
- 5 sites in Norway
- Volunteers
- 35 people
- Sponsor
- Helse Fonna
Functional Dyspepsia, Probiotics
Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia
Objective: This study aims to evaluate the effectiveness of Clostridium butyricum in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria.
- Conditions
- Functional Dyspepsia, Probiotics, Depression, Anxiety
- Trial name
- NCT07182890
- Testing
- Clostridium butyricum
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Functional Dyspepsia(FD) Was Studied, Effect of Simotang on FD Was Studied
Safety Study of a Chinese Herbal Formula Simotang Oral Liquid for the Treatment of Functional Dyspepsia
Functional dyspepsia (FD) is a common functional gastrointestinal disorder and is steadily becoming a public health problem.Simotang is a classical formula that has been used to treat gastrointestinal disorders for hundreds of…
- Trial name
- SMT (NCT01232114)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Hunan University of Traditional Chinese Medicine
NSAID Related Gastric Irritation
Pilot Study of OXP001 and Brufen in Healthy Subjects
Oxford Pharmascience (the sponsor) is developing a new formulation of Ibuprofen (OXP001 - the study drug) which it is proposed will have less of the side effects than are currently reported with standard prescription strength…
- Trial name
- NCT02050958
- Testing
- OXP001, Ibuprofen
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Oxford Pharmascience Ltd
Functional Dyspepsia
Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia
This study is a multi-center, randomized, active-controlled, double-blind, non-inferiority, phase III clinical trial evaluating efficacy and safety of once-daily mosapride (UI05MSP015CT) in patients with functional dyspepsia.
- Trial name
- NCT03225248
- Testing
- UI05MSP015CT, Gasmotin
- Volunteers
- 143 people
- Sponsor
- Korea United Pharm. Inc.
Functional Dyspepsia
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Functional Dyspepsia
Patients with dyspeptic symptoms vary from 10% to 20% globally. Up to 70% of patients with dyspepsia who undergo endoscopy have unremarkable examination and are diagnosed with functional dyspepsia (FD).
- Trial name
- NCT04668534
- Testing
- taVNS 10, taVNS 25, Control
- Where
- 3 sites in China
- Volunteers
- 300 people
- Sponsor
- Air Force Military Medical University, China
Dyspepsia
Melatonin in Pediatric FD Population
There are two specific aims in this study. Specific Aim 1: Determine if melatonin results in a higher grade of clinical response than does placebo in children with functional dyspepsia (FD).
- Trial name
- NCT04684199
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Children's Mercy Hospital Kansas City