Clinical trials: Functional Deficits, active
Stroke, Attention Disorder
Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury
Stroke is the leading cause of long-term disability with an increasing incidence, especially in young adults. Among the cognitive difficulties following brain damage, deficits in attention are frequent and pervasive, affecting…
- Trial name
- NCT05728840
- Testing
- Immersive virtual reality gamified cognitive activities, Double neuropsychological standard activities
- Where
- Switzerland
- Volunteers
- 135 people
- Sponsor
- Mindmaze SA
Autism, ADHD
Spanish-language Executive Function Intervention for Children With Autism and/or ADHD
The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking…
- Trial name
- NCT07084324
- Testing
- Unstuck and On Target
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Attention Deficit Hyperactivity Disorder (ADHD)
Cognitive-Motor Training With the DextEgg in Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is frequently accompanied by deficits in executive functions and fine motor skills, which affect daily activities, academic performance, and health-related quality of life.
- Trial name
- ADHD DextEgg (NCT07913997)
- Testing
- Cognitive-motor DextEgg training, Motor-only DextEgg training
- Volunteers
- 50 people
- Sponsor
- Manuela Pastore-Wapp
Glioma, Glioma Intracranial
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
This study uses a cranial implant to deliver cortical stimulation that, when paired with physiotherapy, will remap the brain so that critical brain functions can be protected during brain tumor surgery.
- Conditions
- Glioma, Glioma Intracranial, Gliomas Benign, Brain Tumor
- Trial name
- NCT04745156
- Testing
- RNS System Implantation
- Volunteers
- 3 people
- Sponsor
- Medical College of Wisconsin
Attention-deficit/Hyperactivity Disorder
An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening
The goal of this study is to extend the efficacy evidence of sustained release methylphenidate compound (JornayPM) in adults with Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT06577779
- Testing
- Methylphenidate Hydrochloride Extended Release Capsule
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Attention-Deficit/Hyperactivity Disorder (ADHD)
Investigation of the Association of Multimodal Neuroimaging and Peripheral Biomarkers With Executive Functions and Emotional Regulation in Adolescents With Attention-Deficit/Hyperactivity Disorder
The purpose of this observational study is to investigate the relationships among resting-state brain connectivity, peripheral blood biomarkers, executive functions, and emotional regulation in adolescents with…
- Trial name
- NCT07800117
- Testing
- No Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Attention Deficit Hyperactivity Disorder Combined
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high levels of impulsivity and…
- Trial name
- AMPAIII (NCT04421248)
- Testing
- Methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Donald Gilbert, MD, MS, FAAN, FAAP
Multiple Sclerosis, Cognitive Impairment
MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis
This is a phase II/exploratory clinical trial with a single-center, open-label design to evaluate the effect of modafinil on cognitive deficits in adult patients with multiple sclerosis and identify predictors of response using…
- Trial name
- MODAFIMS (NCT06592352)
- Testing
- Modafinil Generis 100 mg
- Where
- Portugal
- Volunteers
- 64 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Brain Injury, Neuropsychological Deficits
Cognitive Functions in Severe Acquired Brain Injury After Cranioplasty
Cranioplasty is the main reconstructive neurosurgical procedure, performed in approximately 80% of patients who have previously undergone demolitive surgeries in an emergency setting, particularly in the case of decompressive…
- Conditions
- Brain Injury, Neuropsychological Deficits, Cranioplasty, Cognitive Deficit Following Brain Lesions
- Trial name
- NeC (NCT06895109)
- Testing
- improvement of cognitive functions and psychological aspects
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
ADHD - Attention Deficit Disorder With Hyperactivity
Evaluation of the Relationship Between Medication, Eye Movements, and Autonomic Nervous System (ANS) Functions in Children and Adolescents With ADHD
An increasing number of children are being diagnosed with ADHD, and the demand for ADHD medication has been rising. Although ADHD medication is often effective, this is unfortunately not the case for all children and adolescents…
- Trial name
- POP-Eye/ANSA (NCT07634809)
- Testing
- metylphenidate
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Umeå University
Acute Stroke, Upper Limb Motor Deficit
Effect of Early Tendon Vibrations on Upper Limb Motor Recovery After a Stroke
Strokes often induce a motor deficit. The resulting immobilization is in itself an aggravation factor since it worsens the motor deficit induced by the stroke itself.
- Trial name
- VIBRASTROKE (NCT07905625)
- Testing
- TVS rehabilitation sessions
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Degenerative Cervical Spinal Stenosis
A Novel Surgical Criteria for Degenerative Cervical Myelopathy in Chinese Ethnicity
Degenerative Cervical Myelopathy (DCM) is an age-related irreversible degenerative disease predominantly affecting the elderly aged 50 and over.
- Trial name
- NCT06528730
- Testing
- DCM
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Adult Attention Deficit Hyperactivity Disorder
Effects and Mechanisms of Transcranial Direct Current Stimulation Combined With Dialectical Behavior Therapy Skills Training in Adults With Attention-Deficit/Hyperactivity Disorder
Effects and Mechanisms of Transcranial Direct Current Stimulation Combined with Dialectical Behavior Therapy Skills Training in Adults with Attention-Deficit/Hyperactivity Disorder Abstract Adult attention-deficit/hyperactivity…
- Trial name
- NCT07565402
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Neurologic Disorder, Subarachnoid Hemorrhage, Aneurysmal
Hippocampal Volume and Memory Functions in Aneurysmal Subarachnoid Hemorrhage
Neuropsychological and functional long-term consequences of subarachnoid hemorrhages (SAH) represent a great challenge, since sometimes considerable cognitive deficits occur without evidence of substantial brain damage.
- Trial name
- NCT04449666
- Testing
- Neuropsychological assessment and structural MRI
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Attention Deficit Disorder With Hyperactivity (ADHD), Attention Deficit Disorder (ADD)
A Quick and Reliable Eye Movement Test to Help Diagnose ADHD in Children.
Attention Deficit Hyperactivity Disorder (ADHD) affects more than 5 % of children and adolescents, with a globally increasing prevalence.
- Trial name
- ADHDin15? (NCT07136259)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Onovis Augenpraxis
Cognitive Function, Quality of Life
EFFECT OF PERCEPTUAL-MOTOR TRAINING ON COGNITIVE FUNCTIONS, MOTOR ABILITIES AND QUALITY OF LIFE IN CHILDREN WITH ATTENTION DEFICIT HYPERACTIVE DISORDER
This study aims to Determine the effect of perceptual-motor training on: cognitive functions, motor abilities, and quality of life in ADHD children.
- Conditions
- Cognitive Function, Quality of Life, ADHD - Attention Deficit Disorder With Hyperactivity, Motor Abilities
- Trial name
- NCT07139210
- Testing
- perceptual motor training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Epilepsy
Evaluation of the Risk of Cognitive Deficit After Surgery of Epilepsy by Dynamic Spectral Imaging (ISD) of the Cognitive Functions in Patients Explored in StereoElectroEncephaloGraphy (SEEG)
Epilepsy affects between 0.5 and 0.7% of the European population. Despite the availability of numerous drug treatments, one third of patients still have seizures, which are associated with significant cognitive and social…
- Trial name
- ISD SEEG (NCT03094312)
- Testing
- Dynamic Spectral Imaging (ISD)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon