Clinical trials: Functional Constipation, open to volunteers
Infantile Colics, Constipation
Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete
This is a randomized, single-blind, placebo-controlled study to evaluate the efficacy of the dietary supplement BioAmicus Complete (oral drops; a mixture of 10 strains of lacto- and bifidobacteria) in managing functional…
- Conditions
- Infantile Colics, Constipation, Infantile Diarrhea, Atopic Dermatitis
- Trial name
- NCT07444008
- Testing
- BioAmicus Complete
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- NovoNatum Ltd
Functional Constipation (FC)
Implementation of Physical Therapy Protocol for Functional Constipation
The goal of this randomized controlled trial is to investigate the effects of standard medical treatment alone and the effects of adding different physiotherapy protocols to standard medical treatment on constipation severity…
- Trial name
- NCT07719504
- Testing
- Standard medical treatment, Maitland orthopedic manual therapy (MOMT), Russian current stimulation (ERS)
- Volunteers
- 60 people
- Sponsor
- Cairo University
Constipation - Functional, Fecal Microbiota Transplantation (FMT)
The Safety and Efficacy of Fecal Microbiota Transplantation Combined With Nutritional Intervention in the Treatment of Functional Constipation：a Pilot Study
Chronic constipation is a common gastrointestinal disease with a global prevalence of about 15%, significantly affecting daily life and quality of life.
- Conditions
- Constipation - Functional, Fecal Microbiota Transplantation (FMT), Chronic Constipation
- Trial name
- NCT07387952
- Testing
- FMT
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Peking Union Medical College Hospital
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome
Irritable bowel syndrome is characterized by the presence of chronic, recurrent abdominal pain, alterations in bowel habits, and abdominal distension. The medical diagnosis is made using the Rome IV criteria.
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT07103772
- Testing
- Ananá
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Dyssynergic Defecation
Effects of Connective Tissue Massage Plus Biofeedback for Dyssynergic Defecation
The goal of this randomized controlled clinical trial is to evaluate the effects of connective tissue massage (CTM) added to electromyographic biofeedback (EMG-BF) in adults with dyssynergic defecation (DD).
- Trial name
- NCT07890727
- Testing
- Electromyographic Biofeedback (EMG-BF), Connective Tissue Massage (CTM)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Selcuk University
Irritable Bowel Syndrome, Constipation
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Constipation (IBS-C).
- Trial name
- RENEW-IBS-C (NCT07545772)
- Testing
- LY3537031
- Where
- 70 sites in United States, Belgium and 6 more
- Volunteers
- 342 people
- Sponsor
- Eli Lilly and Company
Irritable Bowel Syndrome
Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome Without Constipation
Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis.
- Trial name
- TRAMIR (NCT05803980)
- Testing
- Fecal microbiota transplantation (FMT)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Constipation - Functional
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption.
- Trial name
- NCT07202481
- Testing
- Psyllium powder, Fructooligosaccharide
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of Minas Gerais
Constipation - Functional, Refractory Constipation
Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation
The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients.
- Conditions
- Constipation - Functional, Refractory Constipation, Fluoxetine, fMRI
- Trial name
- NCT06221722
- Testing
- BOLD-fMRI, Regular treatment of functional constipation, fluoxetine
- Where
- 3 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation
Efficacy of Chatbot for Irritable Bowel Syndrome (IBS) Patients
The goal of this clinical trial is to evaluate the efficacy of an automated chatbot system in improving quality of life, reducing depression and anxiety, and decreasing visceral sensitivity in patients with Irritable Bowel…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation, Irritable Bowel Syndrome - Diarrhoea, Irritable Bowel Syndrome - Mixed
- Trial name
- IrBiS (NCT06837064)
- Testing
- Chatbot supporting system
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Lower Urinary Tract Symptoms (LUTS), Transition Care
Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent Years
With this study, we would like to interview 16-25-year-olds who have experienced urinary problems since childhood and who are still experiencing symptoms in young adulthood.
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Transition Care, Enuresis Nocturnal, Adverse Childhood Experiences
- Trial name
- STREAMWAY (NCT07339865)
- Testing
- Semi-structured in-depth interviews with standardized validated questionnaires, Completion of a urological time-line
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Fecal Incontinence, Outlet Dysfunction Constipation
Treatment of Fecal Incontinence and Functional Evacuation Disorders Using Non-instrumental Biofeedback
Background. Rehabilitation and re-education using instrumental anorectal biofeedback are the main treatment of anorectal functional disorders producing incontinence and outlet obstructed defecation.
- Trial name
- NCT06273046
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Indigestion, Dyspepsia
A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms
The goal of this observational study is to evaluate if Danning Tablets are effective in alleviating dyspepsia in patients with any of the following digestive symptoms: upper abdominal pain, bloating, loss of appetite, acid reflux…
- Conditions
- Indigestion, Dyspepsia, Bloating, Loss of Appetite
- Trial name
- NCT06755671
- Testing
- Danning Tablet
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Hutchison Pharmaceuticals Limited
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postpartum Constipation
Effect of Electroacupuncture on Bowel Function and Quality of Life in Postpartum Constipation: A Randomized Controlled Trial
Postpartum constipation is a common condition affecting women after childbirth, leading to discomfort and reduced quality of life. Pharmacological treatments may have side effects and are sometimes avoided during breastfeeding.
- Trial name
- NCT07572786
- Testing
- electroacupuncture, abdominal exercises for constipation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MTI University
IBS, Constipation Predominant
The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation
The study will aim to evaluate the effectiveness of the use of a food supplement, based on a green tea extract (Camellia sinensis (L.) Kuntze - folium) and a pool of probiotics (L. plantarum, L. rhamnosus and B. animalis subsp.
- Trial name
- NCT07094035
- Testing
- food supplement based on a mixture of green tea extract and a pool of probiotics.
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Adamas Biotech S.r.l.
Colic, Infantile, Milk Allergy, Cow's
Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)
It's common for infants to be unsettled, especially in the first few months of life. While this is often normal, persistent symptoms can be stressful for families.
- Conditions
- Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema)
- Trial name
- NCT07121062
- Testing
- Online parent administered questionnaire
- Where
- United Kingdom
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Refractory Constipation, Somatic Symptom Disorder (DSM-5)
Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features
This single-center, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of fluoxetine (40 mg/day) versus placebo in 194 adults with refractory chronic constipation exhibiting Somatic Symptom…
- Conditions
- Refractory Constipation, Somatic Symptom Disorder (DSM-5), Functional Constipation (FC)
- Trial name
- REFLECT (NCT06506136)
- Testing
- Fluoxetine
- Volunteers
- 194 people
- Sponsor
- Zhifeng Zhao, PhD
Irritable Bowel Syndrome
Effect of Functional Magnetic Therapy on Constipation Predominant- Irritable Bowel Syndrome (IBS-C)
The aim of this study is to evaluate the potential benefits of functional magnetic therapy on constipation improvement and related symptoms in patients with IBS-C, including abdominal pain, bloating, bowel habits, and quality of…
- Trial name
- NCT07256262
- Testing
- Functional magnetic stimulation (FMS), Conventional pharmacological therapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Beni-Suef University