Clinical trials: Functional Constipation
Constipation - Functional, Abdominal Distension
Stress Ball and Video Distraction During Pediatric Enema
This randomized controlled trial aims to evaluate the effects of stress ball use and video distraction during enema administration on fear, anxiety, and pain levels in children treated in the pediatric emergency department.
- Trial name
- SAVE (NCT07695428)
- Testing
- Stress Ball, Video Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Manisa Celal Bayar University
Constipation - Functional, Constipation
The ReVo Study: Low-volume vs High-volume Rectal Irrigation
Rectal irrigation, which is the introduction of warm tap water through the anal canal into the rectum to initiate defaecation, is recommended to be considered in patients with chronic constipation, which is refractory to…
- Conditions
- Constipation - Functional, Constipation, Constipation by Outlet Obstruction, Defecation Disorder
- Trial name
- ReVo (NCT06100055)
- Testing
- Rectal Irrigation
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Functional Constipation (FC)
This is a Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Efficacy and Safety of 2 Weight-based Treatment Groups of Plecanatide Versus Placebo in Children and Adolescent Participants 6 to Less Than 18 Years of Age With FC
The goal of this clinical trial is to learn if plecanatide can treat functional constipation in children and adolescents aged 6 to less than 18 years.
- Trial name
- Trulance (NCT07723924)
- Testing
- plecanatide
- Where
- 29 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bausch Health Americas, Inc.
Functional Constipation
Core-Based Movement and Nutritional Counselling for Stress and Metabolic Outcomes in Overweight Women With Functional Constipation
This study will investigate the effect of core-based movement and nutritional counselling on stress, serum cortisol, and lipid profile in overweight women with functional constipation.
- Trial name
- NCT07694830
- Testing
- Guideline-Based Nutritional Counselling, Core-Based Movement Exercise Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Constipation, Constipation - Functional
The Effects of TTNS, TTNS Combined With PHUS, and Conventional Therapy With PHUS in the Treatment of PFC.
This study is a randomized, controlled trial designed to evaluate the effects of transcutaneous tibial nerve stimulation (TTNS), TTNS combined with pocket-sized handheld ultrasound (PHUS), and conventional therapy with PHUS on…
- Trial name
- constipation (NCT07077044)
- Testing
- The transcutaneous posterior tibial nerve stimulation device, PSUS
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Functional Constipation (FC)
Fiber Nutritional Supplement for Management of Constipation During Pregnancy
This study aims to evaluate the effectiveness of a daily Fiber Nutritional Supplement (Materna® Opti fiber), containing partially hydrolyzed guar gum (PHGG) and vitamins C, D, zinc, and selenium, combined with nutritional…
- Trial name
- NCT07588633
- Testing
- fiber supplement (PHGG) with counselling for constipation management
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Constipation - Functional
Cross-Cultural Adaptation, Validity, and Reliability of the Wexner Questionnaire in Patients With Constipation
The investigators will conduct a validity and reliability study of the Wexner Constipation Questionnaire, used for constipation, in Turkish.
- Trial name
- NCT07340203
- Testing
- survey
- Where
- Turkey (Türkiye)
- Volunteers
- 202 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Faecal Incontinence, Constipation - Functional
Peristeen Light Explorative Clinical Investigation
The goal of this exploratory clinical investigation is to understand the clinical benefits of Peristeen Light in adult patients with faecal incontinence, chronic constipation and/or time-consuming bowel management procedures.
- Trial name
- NCT07126327
- Testing
- Peristeen Light - trans anal irrigation system
- Where
- 2 sites in Denmark, Italy
- Volunteers
- 60 people
- Sponsor
- Coloplast A/S
Refractory Constipation, Somatic Symptom Disorder (DSM-5)
Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features
This single-center, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of fluoxetine (40 mg/day) versus placebo in 194 adults with refractory chronic constipation exhibiting Somatic Symptom…
- Conditions
- Refractory Constipation, Somatic Symptom Disorder (DSM-5), Functional Constipation (FC)
- Trial name
- REFLECT (NCT06506136)
- Testing
- Fluoxetine
- Volunteers
- 194 people
- Sponsor
- Zhifeng Zhao, PhD
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Constipation - Functional
Breath Gases, Gut Flora, and Immunity in Children With Constipation
Constipation is a common problem in children that can affect their daily life, school performance, and social activities. Researchers have found that the bacteria living in our intestines (called "gut microbiome") may play an…
- Trial name
- NCT07797491
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Functional Constipation (FC)
Implementation of Physical Therapy Protocol for Functional Constipation
The goal of this randomized controlled trial is to investigate the effects of standard medical treatment alone and the effects of adding different physiotherapy protocols to standard medical treatment on constipation severity…
- Trial name
- NCT07719504
- Testing
- Standard medical treatment, Maitland orthopedic manual therapy (MOMT), Russian current stimulation (ERS)
- Volunteers
- 60 people
- Sponsor
- Cairo University
Rectum Diameter, Constipation
Measurement of Ultrasonographic Rectal Diameter in Children With Constipation
The aim of this study is to evaluate the diagnostic accuracy of rectal diameter measured by ultrasonography in predicting constipation defined by clinical criteria.
- Conditions
- Rectum Diameter, Constipation, Rome IV Functional Constipation
- Trial name
- NCT07656896
- Testing
- Ultrasonographic rectal diameter measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Parkinsons Disease (PD), Constipation - Functional
Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD).
- Trial name
- NUTRI-GUT-PD (NCT07213856)
- Testing
- Dietitian-Guided Nutritional Intervention
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Functional Constipation
Probiotics for Constipation Relief in Adults
This study aims to evaluate the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa36 in adults with functional constipation.
- Trial name
- NCT07507955
- Testing
- Probiotic, Maltodextrin, High-activity probiotic group
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Functional Constipation (FC), Accidental Falls
Functional Constipation and Fall-Related Outcomes in Older Adults
This retrospective cross-sectional observational study aims to examine the relationship between Rome IV functional constipation and fall history, functional capacity, and physical activity in older adults.
- Conditions
- Functional Constipation (FC), Accidental Falls, Physical Functional Performance
- Trial name
- FC-FALLS (NCT07630740)
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Izmir Bakircay University
Functional Colonic Disease, Fecal Incontinence
Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility
The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.
- Trial name
- NCT00213317
- Testing
- lombo-sacral magnetic stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Constipation - Functional, Constipation-predominant Irritable Bowel Syndrome
MOWOOT Device Treatment for Adults With Chronic Constipation
The primary objective is to compare the effectiveness of the experimental Intermittent Colonic Exoperistalsis (ICE) treatment with MOWOOT, with the active control of trans-anal irrigation (TAI) as standard-of-care.
- Conditions
- Constipation - Functional, Constipation-predominant Irritable Bowel Syndrome, Constipation Chronic Idiopathic, Constipation; Neurogenic
- Trial name
- MOTACC (NCT04666155)
- Testing
- Intermittent Colonic Exoperistalsis with MOWOOT device, Standard of care with Trans-Anal Irrigation
- Where
- 3 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- usMIMA S.L.