Clinical trials: Functional; Anesthesia
Renal Failure Chronic, Transplant;Failure,Kidney
Enhancing Renal Graft Function During Donor Anesthesia
Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney.
- Conditions
- Renal Failure Chronic, Transplant;Failure,Kidney, Anesthesia
- Trial name
- NCT03778944
- Testing
- Mannitol infusion, Dopamine infusion, Adequate hydration
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nazmy Edward Seif
Anesthesia, Epidural
Using the CompuFlo® CathCheck™ System to Check Epidural Catheter Function Before Tubal Ligation: A Pilot Study
This pilot study evaluates the use of the CompuFlo® CathCheck™ System to assess labor epidural catheter function before reactivation for postpartum tubal ligation.
- Trial name
- NCT07720908
- Testing
- CompuFlo® CathCheck™ System Assessment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University
Healthy, Covert Consciousness
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
This research is studying whether mental functions take place during different levels of anesthesia, using a commonly used drug (either dexmedetomidine [with propofol in some participants] or ketamine), which shows areas in the…
- Trial name
- NCT07705022
- Testing
- Dexmedetomidine (+propofol as indicated), Ketamine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Laparoscopic Cholecystectomy
Lung Ultrasound, Cholecystectomy, Atelectasis
Atelectasis is an important complication that can be seen during general anesthesia, especially in patients with lung problems and in patients having pneumoperitoneum.
- Trial name
- NCT06664658
- Testing
- peep 5, peep 10
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Coronary Disease
Renal Function in Patients Submitted to Myocardial Revascularization Surgery
Acute renal insufficiency (ARI) represents a frequent and serious complication in patients submitted to cardiac surgery, and is associated with increases in time of hospitalization, costs, morbidity and mortality.
- Trial name
- NCT00905775
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Osteoarthritis Shoulder
Diaphragm-Sparing Regional Anesthesia Techniques for Shoulder Surgery
This study will compare two regional anesthesia techniques for shoulder surgery and evaluate their effects on diaphragmatic function.
- Trial name
- NCT07474896
- Testing
- Ropivacaine 0.2% for Interscalene Block, Ropivacaine 0.2% for Infraclavicular and Suprascapular Nerve Blocks
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Poznan University of Medical Sciences
Preoperative, Phentolamine
Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery
The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.
- Conditions
- Preoperative, Phentolamine, Intraoperative, Esmolol
- Trial name
- NCT06620991
- Testing
- Phentolamine, Esmolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Anesthesia
Comparison of 4.0 mg/kg Sugammadex at 1-2 Post Tetanic Counts (PTC) in Renal or Control Patients (19.4.328)(P05769)
The current trial was designed to investigate the effects of 4.0 mg.kg-1 of sugammadex on efficacy, safety and pharmacokinetics in subjects with severe renal impairment in comparison to subjects with normal renal function.
- Trial name
- NCT00702715
- Testing
- sugammadex
- Volunteers
- 69 people
- Sponsor
- Merck Sharp & Dohme LLC
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Hypoxemia, Conscious Sedation
Impact of Nasal Mask Versus Nasal Cannula Oxygenation on Hypoxemia in Gastrointestinal Endoscopy: A Brain Function Monitoring (SedLine)-Guided Randomized Controlled Trial (NAMSHIC)
This randomized controlled trial compared the efficacy of a nasal mask versus a standard nasal cannula for oxygen delivery during gastrointestinal endoscopic procedures performed under target controlled propofol infusion…
- Trial name
- NAMSHIC (NCT07500779)
- Testing
- Nasal Mask Oxygenation, Nasal Cannula Oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Anesthesia, Consciousness, Loss of
Detection and Classification of Levels of Consciousness Using Parietal EEG-fNIRS During Anesthesia
The current evaluations of the levels of consciousness during anesthesia have limited precision. This can produce negative clinical consequences such as intraoperative awareness or neurological damage due to under- or…
- Trial name
- NCT05112042
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Leukocyte Function, Anesthesia
The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo
One of the most common side effects of a surgical procedure is infection. In order to lower the number of infections that occur after surgery, it is important for physicians to know how medications used during surgery affect the…
- Trial name
- NCT02207842
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Boston Children's Hospital
Disorder of Pacing Function
3D Echocardiographic Assessment of Epicardial Pacing After Cardiopulmonary Bypass.
This study evaluates the usefulness of 3D echocardiography to guide pacemaker therapy in the operating room in cardiac surgical patients. Each patient will serve as his own control, following a paired design.
- Trial name
- NCT02842762
- Testing
- Right ventricular epicardial pacing, cardiac surgery, 3D TEE
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Suzanne Flier, MD
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University