Clinical trials: Frailty at Older Adults
Frailty, Geriatrics
Combating Hospital-related Function Decline Among Prefrail Older Adults: A Pilot Study
This study focuses on the "Strength-based Tailored-Exercise Program at Home (STEP@Home)" aimed at improving health outcomes for geriatric patients at risk of hospitalization-associated functional decline.
- Trial name
- STEP@Home (NCT06191276)
- Testing
- STEP@Home Intervention, Usual care
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Frailty At Older Adults
Telerehabilitation on Physical Fitness, Functional Status, and Quality of Life in Frail Older Adults
The goal of this randomized controlled trial (RCT) is to analyze whether the effectiveness of a synchronous telerehabilitation program is better than a face-to-face physical therapy program in improving the physical fitness…
- Trial name
- Teleactivate 3 (NCT06784245)
- Testing
- TeleActivate
- Where
- Chile
- Volunteers
- 58 people
- Sponsor
- Marina Alvarado
Frailty at Older Adults, Sarcopenia
A Clinical Study on the Improvement of Frailty and Sarcopenia in Elderly Community Residents Through Pulsed Electromagnetic Field Therapy
The entire clinical study will be conducted strictly following the following procedure: 1) Informed Consent If you decide to participate in this trial, we will first ensure that you fully understand the research purpose…
- Trial name
- NCT07834697
- Testing
- Standard treatment with pulsed magnetic therapy apparatus, Fake stimulation therapy with pulse magnetic therapy device
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Frail Elderly Persons
SUPPORT FOR FRAIL ELDERLY PERSONS - From Prevention to Palliation
The present study "Elderly person in the risk zone" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www.
- Trial name
- NCT00877058
- Testing
- preventive home visit, senior meetings
- Where
- Sweden
- Volunteers
- 459 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Frailty at Older Adults
Motivational Support for an Autonomous Exercise Program for Healthy Aging
An effective implementation of an exercise programme such as VIVIFRAIL, in an unsupervised mode, requires a careful consideration of the patient's motivational traits and state, and the adaptation of the interventions to the…
- Trial name
- MOTIVA (NCT07447453)
- Testing
- MOTIVA ecosystem
- Where
- 2 sites in Spain
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Frailty, Geriatric Syndromes
Beneficial Effects of an Integrated Program of Multicomponent Physical Exercise. Cohort Study
The study has been designed to analyze the possible positive effects of a multicomponent physical exercise program monitored with an integrated electronic device system in dwelling-community frailty older adults.
- Conditions
- Frailty, Geriatric Syndromes, Functional Recovery
- Trial name
- Ros-Ita (NCT04711785)
- Testing
- Multicomponent exercise program
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Frail Elderly Syndrome, Transitional Care
Models of Care in the Transition From the Secondary to the Primary Sector Among the Frailest Elderly
In most Western countries the elderly population increases rapidly. In Denmark, the population of elderly aged 75 years or older may amount to nearly 15 % of the entire population in 2050 compared to 9 % today (2017).
- Conditions
- Frail Elderly Syndrome, Transitional Care, Frailty, Readmission
- Trial name
- NCT03796923
- Testing
- Early follow-up visit after discharge, Comprehensive geriatric assessment (CGA), Continued geriatric care
- Where
- Denmark
- Volunteers
- 3,340 people
- Sponsor
- University of Aarhus
Frailty Syndrome
PREhabilitation of Frail Elderly PAtients Undergoing majoR surgEry at HOME (PREPARE-HOME) Using Smart Wearables
The goal of this clinical trial is to evaluate whether a prehabilitation program using wearable technology can improve physical function and postoperative outcomes in elderly patients (65 years or older) undergoing major elective…
- Trial name
- PREPARE@HOME (NCT06633614)
- Testing
- Supervised prehabilitation programme
- Volunteers
- 190 people
- Sponsor
- Singapore General Hospital
Falls, Frailty
VIVI-OLIVE: Multicomponent Exercise and Extra Virgin Olive Oil in Older Adults at High Risk of Falls
VIVI-OLIVE is a multicenter randomized clinical trial evaluating whether a 24-month intervention combining an individualized multicomponent exercise program (VIVIFRAIL), Mediterranean diet counselling, and supplementation with 60…
- Trial name
- VIVI-OLIVE (NCT07829484)
- Testing
- VIVIFRAIL multicomponent exercise program, Mediterranean diet counselling, Extra virgin olive oil supplementation
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundacion Miguel Servet
Healthy Volunteers
Screening for Frailty at Home
"Many tools to evaluate frailty have been developed. However, at the time our study was designed, none of these instruments had been validated in terms of psychometric properties.
- Trial name
- SEGAm (NCT02852200)
- Testing
- SEGAm
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Frailty
Prevalence of Frailty Among People Aged 75 and Over Living at Home
The aging of population lead to study ways to prevent dependence. Frailty is a precursor to dependence which can be reversible. In the literature, estimate of prevalence of frailty is highly variable depending on the frailty…
- Trial name
- FRAIL-DOM (NCT05163457)
- Testing
- Data collection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Université de Reims Champagne-Ardenne
Geriatric, Palliative Care
PALLIATIVE ASSESSMENT COHORT IN THE GERIATRIC EMERGENCY SETTING
The PALMA project is part of a larger palliative research program COPAL in Capital Region of Denmark led by Professor Tom Møller.
- Conditions
- Geriatric, Palliative Care, Socio-demographic Risk, Frailty at Older Adults
- Trial name
- PALMA cohort (NCT06911411)
- Testing
- Prospective observational cohort study., A prospective observational cohort study
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Gastrointestinal Cancers, Frailty at Older Adults
FRAIL and FiND for Chemotherapy Toxicity in GI Cancer
Older adults with gastrointestinal cancer may experience serious side effects during chemotherapy, particularly when they have reduced physical strength, functional limitations, or other health conditions.
- Conditions
- Gastrointestinal Cancers, Frailty at Older Adults, Chemotherapy
- Trial name
- FRAIL-GI (NCT07272538)
- Testing
- No Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ankara Etlik City Hospital
Frailty, Frailty At Older Adults
ASSESSMENT of FRAILTY AS a PROGNOSTIC FACTOR for MORTALITY, DISABILITY, and QUALITY of LIFE AFTER ICU ADMISSION
Between 30% and 40% of elderly patients (over 70 years old) who require hospitalization and treatment in Intensive Care Units (ICU) exhibit a state of frailty.
- Trial name
- FG-UCI (NCT06793462)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Frailty at Older Adults
Social Robot Support for Healthcare Professionals
This study evaluates the effectiveness of integrated care pathway steps supported by social robots. Half of the participants will receive regular care, while for the other half a social robot dialogue will be included as part of…
- Trial name
- NCT03857789
- Testing
- Questionnaire
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Radboud University Medical Center
Frail Elderly Syndrome, Frailty
Keeping Active in Residential Elderly
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- KARE (NCT03141879)
- Testing
- HUR equipment resistance training intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Birmingham
Frail Elderly Syndrome
Frailty Assessment and Treatment Strategies in the Elderly at Risk of Functional Decline in the Community
This study aims to design a patient -centered program to prevent or delay frailty , functional decline and adverse events, and evaluates the effectiveness of the program with a randomized clinical trial.
- Trial name
- NCT03591055
- Testing
- CGA, medication review, exercise and cognitive stimulation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frail Elderly Syndrome, Frailty
Seated Physical Activity in Ageing
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- SPAA (NCT03141866)
- Testing
- Exercise Intervention 1: Move It Or Lose It (MIOLI), Exercise Intervention 2: Machine-based resistance training intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham