Clinical trials: Frailty
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Old Age; Debility, Fall
Effects of Perturbation-based Balance Training on Postural Control and Cortical Modulation in Elderly With Fall Risk
This is a single-blinded randomized controlled trial with pre- and post- measurements. Forty community-dwelling elderly (age> 65 y/o) with fall risk (defined as functional reach test≦25.4 cm) will be recruited and randomly…
- Trial name
- NCT04473885
- Testing
- Perturbation-based balance training
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Frailty, Dementia
Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Homes (MOVE4CARE)
Can a multicomponent exercise program significantly improve physical and cognitive function and reduce fall rates among nursing home residents? To address this question, the present study aims to compare the effectiveness of a…
- Trial name
- MOVE4CARE (NCT07392944)
- Testing
- Multicomponent exercise intervention, stretching and relaxation program
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Frailty
Modulation of the Gut Microbiota and Metabolism in Elderly by Algae Products.
The goal of this clinical trial is to determine whether a fermented black soybean and adlay supplement can improve frailty. The main questions it seeks to answer are: Does the fermented black soybean and adlay supplement improve…
- Trial name
- NCT06882941
- Testing
- Fermented Black Soybean and Adlay Supplement, non-fermented black soybean and adlay supplement
- Where
- Taiwan
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Balance, Kinesiophobia
The Effect of Hemsball in the Older People
This study aimed to determine the effect of hemsball activity on balance, kinesiophobic attitudes, and frailty levels in older male individuals.
- Conditions
- Balance, Kinesiophobia, Frailty, Older People
- Trial name
- NCT07344662
- Testing
- Experimental: Hemsball
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Frailty, Sarcopenia
A Randomized Control Trial of an Intervention to Reverse Frailty and Enhance Resilience Through Exercise and Education
Resistance training done at home and protein supplementation may be the most effective and easiest to implement interventions to reverse frailty and build resilience.
- Trial name
- REFEREE (NCT04628754)
- Testing
- Exercise and protein
- Where
- Ireland
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Sarcopenia
Multicomponent Intervention for Physical Frailty and Sarcopenia
The SPRINTT study will evaluate the efficacy of a multicomponent intervention programme (physical activity, nutritional counselling/dietary intervention, and information and communications technology intervention) compared with a…
- Trial name
- SPRINTT (NCT02582138)
- Testing
- Multicomponent intervention (MCI), Healthy Aging Lifestyle Education (HALE)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Frailty, Social Isolation in Older Adults
A Pilot Study to Explore the Feasibility of Navigator and Coach Support for Community Participation by Older People
Frailty is a multidimensional syndrome in which a person accumulates age-related deficits across life domains, increasingly including social components such as social isolation.
- Conditions
- Frailty, Social Isolation in Older Adults, Frailty in Older Adults
- Trial name
- ENGAGE (NCT07836465)
- Testing
- Navigation support, Coaching support
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bastiaan Van Grootven
Pulmonary Hypertension, Heart Failure
Frailty in Children With Cardiac Disease
Frailty is a complex biologic syndrome of diminished physiologic reserve that leads to decreased resistance to stressors and is associated with adverse health outcomes.
- Conditions
- Pulmonary Hypertension, Heart Failure, Single Ventricle
- Trial name
- NCT02999438
- Testing
- Actigraph to check activity levels at home
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Frail Elderly Syndrome
ICT-supported Multidimensional Approach for Frailty Screening in Community-dwelling Individuals Aged ≥ 65 Years
SUNFRAIL+ is a prospective observational cohort study aimed to carry out a multidimensional assessment of community-dwelling older adults, through an IT platform, which allows to connect the items of the SUNFRAIL frailty…
- Trial name
- SUNFRAIL+ (NCT05646472)
- Testing
- Frailty multidimensional assessment
- Where
- 8 sites in Italy
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Federico II University
Dignity, Old Age; Debility
INNOVATEDIGNITY: Co-designing Digital Health Technologies With Older People in Homecare Settings.
One of the crucial components of successful ageing is to live independently in old age. Yet in UK alone, nearly 300000 older people require assistance with 3 or more essential daily tasks like eating, bathing and mobility which…
- Conditions
- Dignity, Old Age; Debility, Healthy Aging, Digital Technology
- Trial name
- NCT04884711
- Testing
- No Interventions. Participants will be using their everyday digital health technologies., In depth Interviews, Focus Group Discussions
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Brighton
BPPV
Benign Paroxysmal Positional Vertigo (BPPV) in Nursing Homes: Treatment Efficacy and Impact on Balance, Gait and Falls
BPPV is a benign condition of the balance organ, localized in the inner ear, in which calcium crystals loosen up and move freely in the endolymphatic fluid of the inner ear (more specifically in the semi-circular canals).
- Trial name
- NCT05013671
- Testing
- repositioning maneuvers, balance
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Frail Elderly Syndrome
Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome
Assessing frailty syndrome in elderly patients in Almaty To study the features of the clinical course in the group of patients with a pre-frailty and in the group with frailty syndrome
- Trial name
- FRAILTY-KZ (NCT06496022)
- Testing
- Frail scale, Barthel scale, SARC-F
- Where
- Kazakhstan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Oral Health of Older Men
Talking Pen Audio-Interactive Program for Oral Frailty Delay in Community-Dwelling Elderly
This study aims to develop and evaluate the effectiveness of a talking pen audio-interactive technology integrated with an oral frailty delay care program for community-dwelling older adults in rural agricultural regions of…
- Trial name
- NCT07191600
- Testing
- Talking Pen Audio-Interactive Oral Frailty Care Program
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Polypharmacy
Medication Minimization for Long-term Care Residents
The purpose of this experiment is to test the effect of medication minimization on mortality and hospitalization in long-term care residents.
- Trial name
- WiseMed (NCT01932632)
- Testing
- Medication Minimization
- Where
- 6 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Frailty at Older Adults, Health Promotion
Effects of HAPPY GO GO Game on Health of Rural Elderly
The goal of this quasi-experimental clinical trial is to evaluate the effects of the "HAPPY GO GO" somatosensory game on physical and mental health in community-dwelling older adults aged 65 years and above living in rural Chiayi…
- Trial name
- NCT07191613
- Testing
- HAPPY GO GO Somatosensory Game
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Frailty, Old Age
Integrating Health Promotion With and for Older People - eHealth
The Integrating Health promotion with and for Older People eHealth (IHOPe) project is expected to contribute vital knowledge on how older peoples capabilities and societal resources can be used in a more efficient way to promote…
- Trial name
- IHOPe (NCT04416815)
- Testing
- Integrating Health promotion with and for Older People - eHealth
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Osteoporosis
The Oswestry Metabolic BONE Cohort
Osteoporosis is a chronic condition characterised by reduced bone mass and microarchitectural deterioration of bone tissue leading to fracture.
- Trial name
- OsBONE (NCT07014306)
- Testing
- MRI, Computed tomography
- Where
- United Kingdom
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Older Adults
Flexi-Bar and Multi-Component Exercises
Background: Previous studies have suggested that both Flexi-Bar and Multi-Component exercises can improve an individual's physical fitness and musculoskeletal discomfort.
- Trial name
- NCT05025137
- Testing
- Flexi-Bar Exercise, Multi-Component exercise
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil