Clinical trials: Frailty/Sarcopenia
Sarcopenia
Exercise Intervention for Patients With Sarcopenia or Frailty in Long-term Care Institutions
Sarcopenia is a geriatric syndrome of decreased muscle volume with muscular function decline. There is more tendency for sarcopenic elderly to be frail, disabled, or have cardiovascular disease.
- Trial name
- NCT03650907
- Testing
- Group exercise program, Self exercise program
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia, Frailty
Health Data from Well on My Legs Program
The percentage of people aged over 80 will double in 25 years, reaching 10% of the population. This means that care practices for older adults will have to be adapted.
- Conditions
- Sarcopenia, Frailty, Physical Inactivity, Fear
- Trial name
- DS-BSSJ (NCT06659484)
- Testing
- Assessment, Multicomponent exercise program, Follow-up at T3 + 6 months and T3 + 12 months
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stroke, COVID-19
Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
The goal of this feasibility study is to evaluate the use of the Ghostly app in rehabilitation of stroke patients, elderly and patients recovering from COVID-19 or ICU patients.
- Conditions
- Stroke, COVID-19, Frailty, Muscle Weakness
- Trial name
- NCT05258500
- Testing
- Ghostly app, Blood flow restriction, Leaflet
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Liver Disease and Cirrhosis
Impact of Home-Based Aerobic and Resistance Training in Chronic Liver Disease: a Randomized Control Trial
The goal of this clinical trial is to evaluate whether home-based exercise interventions, including aerobic exercise (AE) and a combination of aerobic and resistance exercise (ARE), can improve physical and health-related…
- Trial name
- NCT06892366
- Testing
- Home-Based Aerobic Exercise Program, Home-Based Aerobic and Resistance Exercise (ARE) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Hacettepe University
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Frailty, Frailty/Sarcopenia
Clinical and Functional Effectiveness Assessment of Personalized Management Programs for Patients With Frailty
All participants underwent comprehensive geriatric assessment (CGA) and cardiopulmonary exercise testing (CPET). A personalized management program was developed for each patient, including recommendations on physical exercise…
- Trial name
- NCT07623694
- Testing
- Geriatric rehabilitation program based on CGA and CPET
- Where
- Russia
- Volunteers
- 115 people
- Sponsor
- Pirogov Russian National Research Medical University
Colon Cancer, Malnutrition
The Patient in Laparoscopic Colon Surgery:Impact of Comorbidities,Frailty,Malnutrition and Sarcopenia on Short-term Mortality
There are many factors involved in outlining the patient's profile and in defining which factors can be configured as risks related to the surgical act; for the modern surgeon it is no longer possible to identify the patient at…
- Conditions
- Colon Cancer, Malnutrition, Sarcopenia, Comorbidities and Coexisting Conditions
- Trial name
- NCT04729738
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- University Hospital of Ferrara
Frailty, Surgery
Retrospective Analysis of Sarcopenia in Older Patients Undergoing Laparotomy
Assess the influence of sarcopenia on outcomes of emergency laparotomy in the over 65 age group
- Conditions
- Frailty, Surgery, Emergencies
- Trial name
- NCT04493710
- Testing
- Sarcopenia estimation
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Frailty, Frailty in Older Adults
Comparison of Preoperative Frailty Assessment Tools
Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults.
- Conditions
- Frailty, Frailty in Older Adults, Frailty/Sarcopenia
- Trial name
- PREFAS (NCT06889545)
- Testing
- Assessment of frailty using multiple tools
- Where
- Germany
- Volunteers
- 584 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Metabolic Disease
Effectiveness of Technology for Metabolic Diseases Combined Sarcopenia
The lifestyle program intervention program focusing on healthy dietary habit and exercise effectively prevents metabolic syndrome, sarcopenia or frailty.
- Trial name
- NCT05476536
- Testing
- self-management skills and healthy technology APP
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Sarcopenia, Muscle Loss
Effect of Strength Training and Protein Ingestion in Old Versus Very-old
From 3 interventiongroups in the project with ClinicalTrials.gov ID NCT02034760, namely: HRTW: Heavy Strength Training x3/week \& 20g whey protein twice daily.
- Trial name
- NCT02105922
- Testing
- Heavy Resistance Training, Light Intensity Training, Protein Whey
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Healthy Aging, Sarcopenia
Plant-based Diets and Healthy Aging
This prospective study investigates the health effects of vegetarian and plant-based diets in middle-aged and older adults in Taiwan, specifically, recruiting 5000 Tzu Chi volunteers.
- Conditions
- Healthy Aging, Sarcopenia, Frailty, Cognitive Decline
- Trial name
- TCAS (NCT07151365)
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Sarcopenia
Neuromuscular Electrical Stimulation Study
In this study, the investigators will use feasibility RCT design to determine whether it is justifiable to conduct a large-scale clinical trial of neuromuscular electrical stimulation with or without additional protein…
- Trial name
- IMMI (NCT04792307)
- Testing
- Neuromuscular electrical stimulation , no high protein ice cream supplementation
- Volunteers
- 66 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Sarcopenia, Frailty
Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients
This prospective observational study aims to evaluate whether sarcopenia and frailty affect the pharmacodynamic profile of rocuronium in geriatric patients undergoing elective surgery under general anesthesia.
- Conditions
- Sarcopenia, Frailty, Neuromuscular Blockade, Rocuronium
- Trial name
- NCT07580144
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Meram State Hospital
Sarcopenia
Frailty and Assocciated Factors in Sarcopenia
Primary sarcopenia is a condition that occurs with the aging process and is characterized by symptoms such as decreased muscle mass, impaired muscle function and decreased physical strength.
- Trial name
- NCT06931964
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Sarcopenia, Muscle Loss
Counteracting Age-related Loss of Skeletal Muscle Mass (CALM)
Up to 66 healthy elderly individuals (at least 65 years old) are recruited as subjects. They will be recruited as a subgroup to protocol ID: H-4-2013-070.
- Trial name
- CALM (NCT02115698)
- Testing
- Heavy Resistance Training, Light Intensity Training, Protein Whey
- Where
- Denmark
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Acute Coronary Syndromes (ACS), Cardiac Rehabilitation
Patient-centered Personalized Cardiac Rehabilitation in Post Acute Coronary Syndrome (BREAK-trial)
The primary objective of this study is to compare an integrated, multidisciplinar patient-centered CRP (Cardiac Rehabilitation Program) (intervention group) especially focused on covering the needs for the female and fragile…
- Conditions
- Acute Coronary Syndromes (ACS), Cardiac Rehabilitation, Frailty, Women
- Trial name
- BREAK (NCT07038265)
- Testing
- Personalised treatment, Usual Care
- Where
- Spain
- Volunteers
- 202 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Gastrointestinal Cancers, Frailty
Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer
Older adults with gastrointestinal cancers may be more likely to experience side effects from chemotherapy and difficulties with everyday activities. These problems are not always explained by age alone.
- Conditions
- Gastrointestinal Cancers, Frailty, Sarcopenia in Elderly, Malnutrition Elderly
- Trial name
- VITAL-GI (NCT07184047)
- Testing
- Standard-of-Care Systemic Chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ankara Etlik City Hospital
Oral Frailty, Depression
Group Reading and Oral Exercise Program for Older Adults
Depression is common among older adults and is often associated with declines in physical and oral health. Non-pharmacological, community-based interventions are needed to support both mental and physical well-being.
- Conditions
- Oral Frailty, Depression, Sarcopenia, Physical Function Decline
- Trial name
- NCT07550335
- Testing
- Reading and Oral Exercise Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Critical Illness, Sarcopenia
Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit
The primary aim of the study is to evaluate consequences of frailty in critically ill patients. We hypothesize that a higher frailty index (based on published questionnaires) predicts a longer surgical intensive care unit and…
- Conditions
- Critical Illness, Sarcopenia, Muscle Wasting
- Trial name
- NCT02270502
- Testing
- Ultrasound Philips CX50, Frailty Index Questionnaire, Muscle strength tests
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Massachusetts General Hospital