Clinical trials: Frail Elderly Syndrome
Frailty, Frailty Syndrome
Characterising Frailty Using Magnetic Resonance Imaging
Ageing is associated with the development of various negative conditions, such as frailty. Defined as a decreased ability to combat negative stressors (e.g.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- PHENOFRIM (NCT04612686)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Colon Cancer, Colon Neoplasm
Geriatric Assessment and Intervention in Older Patients Undergoing Surgery for Colorectal Cancer
The GEPOC study investigates the effect of comprehensive geriatric assessment and intervention for frail older patients (65 years or older) undergoing elective surgery for colorectal cancer.
- Conditions
- Colon Cancer, Colon Neoplasm, Frail Elderly Syndrome, Colorectal Cancer
- Trial name
- GEPOC (NCT03719573)
- Testing
- Geriatric intervention
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Herlev and Gentofte Hospital
Heart Failure, Frailty
INTEgRated Health CARE for Patients With Frailty and Heart Failure
Frailty, an aging-related syndrome of physiological decline characterized by marked vulnerability to adverse health outcomes, has attracted increasing attention in cardiology due to the growing elderly population with heart…
- Conditions
- Heart Failure, Frailty, Frail Elderly Syndrome, Symptom, Behavioral
- Trial name
- INTERCARE-HF (NCT06444321)
- Testing
- INTERCARE-HF
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Vestre Viken Hospital Trust
Functional Fitness, Health Promotion
12-week Pilates Program on Community-dwelling Middle-aged Women
The purpose of this study was to investigate the effects of a Pilates exercise intervention program on functional physical fitness in community-dwelling middle-aged women.
- Conditions
- Functional Fitness, Health Promotion, Exercise, Frail Elderly Syndrome
- Trial name
- NCT05333484
- Testing
- Programed Pilates
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Fragility
Mobility Assessment & Follow-up in Frail Elderly: Clinic-technical Validation of a Smart Insole in Real Life
The investigators aim is to evaluate an instrument for supporting physical activity and monitors multiple parameters of frailty (a pre-disability condition) in frail elderly persons.
- Trial name
- RESPECT (NCT02316600)
- Testing
- smart insole
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Frail Elderly Syndrome, Postoperative Delirium
Different Frailty Scores to Incidence of Post-operative Delirium and Cognitive Dysfunction
Patients who are frail will have higher rate for post-operative morbidities, mortality, prolonged hospital stays, loss of independence, increase in institutionalization, post-operative cognitive dysfunction (POCD) and delirium…
- Conditions
- Frail Elderly Syndrome, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT04056871
- Testing
- Frailty Screening Tools
- Where
- Malaysia
- Volunteers
- 400 people
- Sponsor
- University of Malaya
Frailty, Frail Elderly Syndrome
Effect of Baduanjin on Functional Performance in Pre-Frail/Frail Older Adults
The aim for this study is to investigate the effectiveness of a 16-week realistic community-delivered Baduanjin training program compared to a waitlist control intervention, in improving functional outcomes among pre-frail and…
- Trial name
- NCT04549103
- Testing
- Baduanjin exercise program
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- Geriatric Education and Research Institute
Muscle Weakness
Effect of PROGRESSive Training and Teststerone in Older Frail Men
In this scientific clinical investigation we will test whether testosterone and progressive resistance training can improve muscle strength and reduce the risk of falls in older men.
- Trial name
- PROGRESS (NCT02873559)
- Testing
- testosterone, Progressive muscle training
- Where
- 2 sites in Denmark
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Gastric Cancer, Frail Elderly Syndrome
Frailty and Postoperative Outcomes After Gastric Cancer Surgery
Background. Gastric cancer is an important health care problem even though treatment advances, and it is diagnosed mainly in elderly.
- Conditions
- Gastric Cancer, Frail Elderly Syndrome, Postoperative Complications, Quality of Life
- Trial name
- TOREGA (NCT03568110)
- Where
- Spain
- Volunteers
- 432 people
- Sponsor
- Parc de Salut Mar
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Frail Elderly Syndrome
The Importance of Anesthesia Method in Fragile Patients
The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g.
- Trial name
- NCT07191769
- Testing
- general anaesthesia, regional anaesthesia
- Volunteers
- 180 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Frail Elderly Syndrome, Older
eHealth for Screening Health Risks in Home-Based Older Adults: A Prospective Study
Introduction: Due to the worldwide ageing population and the increasing prevalence of chronic illnesses and cognitive deficits, appropriate instruments for frailty early screening and assessment of geriatric syndromes are…
- Trial name
- Proxi (NCT06019390)
- Testing
- Presage care
- Volunteers
- 200 people
- Sponsor
- Presage
Frail Elderly Syndrome
No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study
To assess the cross-sectional and 5-year prospective association between self-reported vitamin C+E dietary supplementation and markers of grip strength and frailty in community-dwelling Swiss adults.
- Trial name
- CoLaus (NCT03258970)
- Testing
- Observational cohort study
- Where
- Switzerland
- Volunteers
- 2,711 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Frail Elderly Syndrome, Aging
Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Frailty-Aging Processes
With increasing age and health issues associated with aging, many systemic cellular and structural changes are known to occur. The intent of this trial is to determine the safety and efficacy of delivery of autologous cellular…
- Conditions
- Frail Elderly Syndrome, Aging, Degenerative Disease
- Trial name
- GARM-W (NCT03514537)
- Testing
- Microcannula harvest adipose stromal tissues, Centricyte 1000, Sterile Normal Saline IV Deployment of cSVF
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Healeon Medical Inc
Frailty Syndrome
Efficacy of WB-EMS in Frail Older People
Exercise in general and resistance training (RT) in particular have demonstrated positive effects on frailty outcomes, including physical functioning.
- Trial name
- NCT04967534
- Testing
- WB-EMS, social contact control group
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Frail Elderly Syndrome, Heart Failure
Medical Monitoring of Older Adults Patients After Discharged From Heart Failure Hospitalization
Introduction: PRESAGE CARE has developed a solution for early detection of the risk of emergency department visits and unscheduled hospitalizations.
- Trial name
- NCT06018532
- Testing
- PRESAGE CARE
- Volunteers
- 100 people
- Sponsor
- Presage
Sedentary Lifestyle, Physical Activity
Coach2Move: Sustainable in Daily Practice
Implementation of a previously shown (cost-)effective physical therapeutic treatment strategy for community-dwelling older adults.
- Conditions
- Sedentary Lifestyle, Physical Activity, Frail Elderly Syndrome
- Trial name
- NCT03212859
- Testing
- Coach2Move, Usual Care
- Where
- Netherlands
- Volunteers
- 292 people
- Sponsor
- Radboud University Medical Center
Congestive Heart Failure, Cancer
Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks
This project compares two models of the Serious Illness Care Program (SICP) in primary care: clinician-focused SICP and team-based SICP.
- Conditions
- Congestive Heart Failure, Cancer, Chronic Obstructive Pulmonary Disease, Cerebrovascular Accident
- Trial name
- NCT03577002
- Testing
- Serious Illness Care Program (SICP)
- Where
- 7 sites in United States, Canada
- Volunteers
- 1,120 people
- Sponsor
- Oregon Health and Science University
Frail Elderly Syndrome, Muscle Weakness
Investigation of Relation With Preoperative Fragility and ASA Score in Elderly Patients
Frailty is a term specific to the geriatric period. It is used to describe weak, unstable, frail patients and partially expresses the frailty of the elderly patient.
- Trial name
- NCT05078983
- Testing
- CGA-FI (COMPREHENSIVE GERIATRIC ASSESMENT - FRAILITY INDEX)
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Gulhane Training and Research Hospital