Clinical trials: Frail Elderly Syndrome
Frail Elderly Syndrome
A Machine Learning Algorithm to Predict Health Clinical Situations in Primary Healthcare for Frail Older Adults.
Introduction: We developed a machine learning algorithm to predict the risk of emergency hospitalization within the new 7 to 14 days with a good predictive performance (AUC=0.85).
- Trial name
- NCT06013709
- Testing
- PRESAE CARE
- Volunteers
- 1,478 people
- Sponsor
- Presage
Acute Heart Failure, Frail Elderly Syndrome
Discharge Planning in Emergency Department for Frail Older With AHF
Objectives: To demonstrate the efficacy of care transition holistic intervention (Multilevel Guided Discharge Planning, MGDP) in reducing 30-day adverse outcomes among frail older patients with acute heart failure (AHF)…
- Trial name
- NCT03696875
- Testing
- Multilevel Guided Discharge Planning, Standard of care
- Where
- Spain
- Volunteers
- 1,260 people
- Sponsor
- F. Javier Martin Sanchez
Geriatric Assessment, Frail Elderly Syndrome
Frailty Prevention in Elders From Reunion Island
In Reunion Island, people encounter environmental and social conditions leading to premature ageing and subsequent frailty. The study evaluates tools, supported by the latest scientific advances in "machine learning" to detect…
- Conditions
- Geriatric Assessment, Frail Elderly Syndrome, Prevention, Fall Patients
- Trial name
- 5P-ECHELLE (NCT05090241)
- Testing
- Instrumental measurement of balance and gait
- Where
- 2 sites in Reunion
- Volunteers
- 147 people
- Sponsor
- Universite de La Reunion
Non-ST Elevation Myocardial Infarction, Frail Elderly Syndrome
the Invasive and Conservative Strategies in Elderly Frail Patients With Non-STEMI
The role of a routine invasive strategy in frail patients with non-ST-segment elevation acute myocardial infarction is currently uncertain. We hypothesize that a routine invasive strategy will improve outcomes.
- Trial name
- MOSCA-FRAIL (NCT03208153)
- Testing
- Invasive, Conservative
- Where
- Spain
- Volunteers
- 167 people
- Sponsor
- University of Valencia
Cognitive Decline, Memory Loss
Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
This research aims to analyze the effects of senior dance on the cognition, frailty, and burden in elderly caregivers of rural communities.
- Conditions
- Cognitive Decline, Memory Loss, Frail Elderly Syndrome, Burden, Dependency
- Trial name
- NCT03068299
- Testing
- Dance, Health care guidance
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Frail Elderly Syndrome, Elderly Infection
Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly
Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system.
- Trial name
- NCT03292744
- Testing
- Alfacalcidol
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Frail Elderly Syndrome
Frailty Prevention Program to Prevent Frailty Among Older African Americans
Between 20-60% of older adults experience frailty as they age. Frailty is a clinical state of increased vulnerability resulting from aging-associated declines in biological reserve across multiple physiologic systems.
- Trial name
- FPP (NCT03585972)
- Testing
- Frailty Prevention Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wayne State University
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Functionality
The pre-frail elderly are a population more vulnerable to diminished functionality and future disabilities. Thus, interventions focused on the prevention of sarcopenia are indicated to prevent dysfunction in this population.
- Trial name
- NCT03688932
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Frail Elderly Syndrome, Surgery
Development and Validation of a Preoperative Frailty Index Using Health Administrative Data
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard…
- Conditions
- Frail Elderly Syndrome, Surgery, Outcomes, Predictive Value of Tests
- Trial name
- NCT03354546
- Testing
- Frailty index
- Volunteers
- 511,285 people
- Sponsor
- Ottawa Hospital Research Institute
Frail Elderly Syndrome, Acute Coronary Syndrome
Frailty Assessment in Elderly Patients With Acute Coronary Syndrome
Frailty is known as an independent risk factor for morbidity and mortality in older cardiac patients . It is an important factor on the cardiologist decision between conservative and invasive treatment in older patient with acute…
- Trial name
- NCT03365505
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Heart Failure, Prefrail Elderly
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure.
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- Trial name
- TeleRiab4Fra (NCT07561021)
- Testing
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Volunteers
- 70 people
- Sponsor
- University of Salerno
Frail Elderly Syndrome
Frailty Assessment and Treatment Strategies in the Elderly at Risk of Functional Decline in the Community
This study aims to design a patient -centered program to prevent or delay frailty , functional decline and adverse events, and evaluates the effectiveness of the program with a randomized clinical trial.
- Trial name
- NCT03591055
- Testing
- CGA, medication review, exercise and cognitive stimulation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pre-frail Elderly
The Effect of Cholecalciferol in Pre-frail Elderly
Vitamin D plays important role in musculoskeletal health and has been known to influence immune system. Inflammaging is one of risk factors that may contribute to development of frailty in elderly.
- Trial name
- NCT04847947
- Testing
- Cholecalciferol
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
ACS, Frail Elderly Syndrome
The Effect of Frailty and Other Geriatric Syndromes on the Prognosis of Elderly Patients With Acute Coronary Syndrome
This is a prospective observational clinical trail which will recruit 1000-1500 participants over 65 years with frailty and acute coronary syndrome (ACS) in Beijing Friendship hospital.
- Conditions
- ACS, Frail Elderly Syndrome, Elderly Patient
- Trial name
- NCT04580706
- Testing
- this is an observational study with none intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Friendship Hospital
Frail Elderly Syndrome, Patient Admission
Geriatric Assessment and Intervention for Older Patients With Frailty in the Emergency Department
Comprehensive Geriatric Assessment (CGA) is an established approach for better detection of frailty-related problems and includes individualized treatment plan with multi-discipline supportive and treating measures for the older…
- Conditions
- Frail Elderly Syndrome, Patient Admission, Hospital Readmission, Length of Stay
- Trial name
- GAOPS (NCT03751319)
- Testing
- CGA
- Where
- Finland
- Volunteers
- 432 people
- Sponsor
- Helsinki University Central Hospital
Sedentary Behavior, Frail Elderly Syndrome
Effect of an Intervention on Health in Older Care Home Residents
Care home residents spent 79% of their time being sedentary. Reduced physical activity and lack of mental stimulation causes general weakness and frailty in older adults that can result in increased healthcare needs.
- Conditions
- Sedentary Behavior, Frail Elderly Syndrome, Frailty, Lifestyle, Sedentary
- Trial name
- NCT04659694
- Testing
- Wellness programme provided by Oomph! Wellness company
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bournemouth University
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
Frail Elderly, Hip Fracture
Effects of Long-term Intensive Home-based Physiotherapy on Older People With an Operated Hip Fracture or Frailty (RCT).
Our objective is to study the effects of 12 months' intensive home-based physiotherapy (physical exercise) with 12 months' follow-up in two groups of older people: 1) those with an operated hip fracture (60+ y), and 2) those with…
- Trial name
- HIPFRA (NCT02305433)
- Testing
- Home-based physiotherapy (physical exercise)
- Where
- Finland
- Volunteers
- 421 people
- Sponsor
- South Karelia, Social and Health Care District
Frail Elderly Syndrome, Mood
FOCUS Guidelines and Adherence to Physical Activity in Ageing Women.
The study aimed at assessing whether the guidelines from the European project FOCUS had an effect on adherence to a physical activity program in older women.
- Conditions
- Frail Elderly Syndrome, Mood, Quality of Life, Cognitive Decline
- Trial name
- NCT03981965
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Heart Failure, Frail Elderly Syndrome
Frailty Heart Failure Study
A prospective longitudinal cohort study aimed at measuring frailty and its associated risk factors community dwelling older adults aged 65 years or older.
- Trial name
- NCT03887351
- Volunteers
- 280 people
- Sponsor
- Jewish General Hospital