Clinical trials: Fractures, open to volunteers
Ankle Fractures, Knee Fractures
Performance and Safety Follow-up of Bioabsorbable Headless Inion CompressOnTM Screws in the Fixation of Bone Fractures in Ankle, Knee and Elbow of Pediatric and Adolescent Patients
The study in question is a post market clinical follow up (PMCF) study to follow up the safety and performance of bioabsorbable headless compression screw Inion CompressOn in fracture fixation of the ankle, knee and elbow of…
- Conditions
- Ankle Fractures, Knee Fractures, Elbow Fractures
- Trial name
- NCT07473947
- Testing
- Fracture fixation operation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Inion Oy
Forearm Fractures
Management of Diaphyseal Forearm Fractures in Adolescents
evaluate and compare the clinical, and radiographic outcomes of 2.7 mm locking compression mini-plate osteosynthesis versus titanium elastic intramedullary nail (TEN) in the surgical management of diaphyseal fractures of both…
- Trial name
- NCT07705347
- Testing
- Open reduction and internal fixation, Closed or mini-open reduction and fixation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Delirium - Postoperative, Low Flow Anesthesia
Low- vs. Normal-Flow Anesthesia and Delirium After Hip Fracture in the Elderly
The aim of this study is to investigate the relationship between low-flow and normal-flow anesthesia techniques and the development of postoperative delirium in elderly patients undergoing surgery for hip fracture.
- Conditions
- Delirium - Postoperative, Low Flow Anesthesia, Elderly Patients (>65 Years), Hip Surgery
- Trial name
- NCT06973967
- Testing
- delirium
- Volunteers
- 128 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Distal Radius Fractures
Impact of Early ADL Education on Outcomes Post DRF ORIF
This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated with surgical intervention of open reduction and internal…
- Trial name
- NCT06251206
- Testing
- ADL/Postoperative Instruction, Postoperative Instruction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- George Washington University
Postoperative Delirium
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia…
- Trial name
- NCT07066111
- Testing
- Tramadol, bupivacaine liposome (ultrasound-guided high iliofascial space block)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb
Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
This study supports Spanish data collection and analysis on Periprosthetic and Peri-implant fractures of the upper and lower limb. Treatment and clinical management of this fractures are complex and goes along with complications.
- Conditions
- Periprosthetic Fracture of the Upper or Lower Limb, Peri-implant Fracture of the Upper or Lower Limb, Periprosthetic Fractures, Peri-implant Fracture
- Trial name
- PIPPAS (NCT04663893)
- Where
- 7 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Olecranon Fracture
Clinical Trial to Evaluate Three Systems of Osteosynthesis for Fixation of Olecranon Osteotomies in Adults
Surgery of the elbow joint is often made difficult by the highly constrained nature of the elbow joint. This is why it is often necessary to perform an osteotomy of the olecranon, the proximal part of the ulna, which allows…
- Trial name
- NCT07014358
- Testing
- Fastening systems by placing two steel pins, Fastening systems by a wire in an obenque configuration, Fastening systems by the placement of a bolted plate or the placement of a compression screw
- Where
- 5 sites in Spain
- Volunteers
- 105 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Pelvis; Fracture
Surgical Treatment of Pelvis in Fragility Fracture in Germany: a Prospective, National, Multicenter, Observational, Comparative Cohort Study Comparing Isolated Posterior Versus Combined Anterior-posterior Surgical Fracture Stabilization
Over a period of approximately two years, patients above the age of 65 who have suffered from an FFP equal to or higher than type IIc FFP, according to Rommens and Hofmann, will be eligible for inclusion.
- Trial name
- AO TOP (NCT06550934)
- Testing
- Fracture stabilization
- Volunteers
- 420 people
- Sponsor
- AO Innovation Translation Center
Breast Cancer
Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors
The purpose of this study to gather information about changes in the bones after stopping treatment with aromatase inhibitor/AI and denosumab.
- Trial name
- NCT05590949
- Testing
- Physical Evaluation, Dual-energy X-ray absorptiometry scans, Trabecular Bone Score
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Trauma (Including Fractures), Trauma ICU Patients
Mortality of Trauma in the Intensive Care Unit.
In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality.
- Conditions
- Trauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICU
- Trial name
- MOTRAM-ICU-COL (NCT07208110)
- Testing
- Exposed to trauma, Not exposed
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Hospital Departamental de Villavicencio
Distal Femur Fracture
DIFFIR - Geriatric Distal Femur Fixation Versus Replacement
The current standard of care for most intra-articular distal femur fractures (above the knee joint) in geriatric patients is a surgical fixation using plates and screws to hold the fracture pieces in the correct position, until…
- Trial name
- DIFFIR (NCT04076735)
- Testing
- Distal femoral replacement, Surgical Fixation (ORIF)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Proximal Humeral Fracture
Clinical Outcomes of the ALPS Proximal Humerus Plating System
The purpose of this study is to document the performance and clinical outcomes of the A.L.P.S® Proximal Humerus Plating System. Specific Aims: Conduct physical assessments measuring shoulder strength and range of motion…
- Trial name
- ALPS PHP (NCT03328650)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Edema, Pneumonia
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second.
- Conditions
- Pulmonary Edema, Pneumonia, Atelectasis, Pleural Effusion
- Trial name
- NCT06538376
- Testing
- Portable Dynamic Digital Radiography (DDR)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Brigham and Women's Hospital
Nerve Block, Hip Fracture Surgeries
Self-Guided Immersive Virtual Reality Versus Mannequin-based Simulators to Teach the Ultrasound-Guided Supra-Inguinal Fascia Iliaca Block
This research project aims to see if using immersive virtual reality (iVR) is as good as using traditional mannequins to teach medical staff how to perform a specific nerve block called an ultrasound-guided supra-inguinal fascia…
- Trial name
- NCT07035015
- Testing
- VR UGRA, Mannequin-based simulation
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Ottawa Hospital
Implantable Defibrillator User, Stress Reaction
Self-Management Interventions After an ICD Shock
This study, "Biobehavioral Intervention to Reduce PTSD Symptoms After an ICD Shock," addresses a critical need in cardiology care by describing the feasibility and acceptability of a timely, highly promising…
- Conditions
- Implantable Defibrillator User, Stress Reaction, Ptsd, Stress Management
- Trial name
- NCT06037785
- Testing
- Self-Paced Self-Management (SPSM)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Osteoarthritis, Knee Injuries
Knee Osteoarthritis in the Region of Norrbotten
The goal of this observational study is to assess the prevalence of radiographic knee osteoarthritis and to report medium and long term functional outcomes secondary to tibia plateau fractures.
- Conditions
- Osteoarthritis, Knee Injuries, Knee Osteoarthritis, Tibial Plateau Fractures
- Trial name
- KORN (NCT06451510)
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Femur Shaft Fracture, Tibia Fractures
Assessing Bone Fracture Healing Effect of Almonds
Femur and tibia shaft fractures are common after trauma with a burden of 5% and 20% respectively. Clinicians recommend costly bone strengthening drugs/supplements while treating bone fractures.
- Conditions
- Femur Shaft Fracture, Tibia Fractures, Vitamin D, Sweet Almonds
- Trial name
- AFHEA (NCT07153302)
- Testing
- Prunus dulcis (sweet almonds)
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University