Clinical trials: Former Smoker
Smoking Cessation
Testing Different Theories of Smoking Cessation: An Intervention Study
The topic of this research is cigarette smoking cessation. We designed four smoking cessation booklets. These booklets are designed for smokers who differ in their motivation to quit smoking.
- Trial name
- NCT01209897
- Testing
- Smoking cessation booklet
- Where
- United States
- Volunteers
- 1,826 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Tobacco Use
Jail-Based Use of Smoking Cessation Treatment Study
Smoking rates remain above 60% for individuals involved in the criminal justice system and contribute to elevated mortality rates in this population.
- Trial name
- JUST (NCT03799315)
- Testing
- Nicotine Replacement Therapy, Counseling
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Respiratory Disorders
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Non-typeable Haemophilus Influenzae (NTHi) Investigational Vaccine (GSK2838497A) in Current and Former Smokers
The purpose of this study is to assess the safety, reactogenicity and immunogenicity of 8 different formulations of investigational NTHI vaccine in current and former smokers, 50-70 years of age.
- Trial name
- NCT01678677
- Testing
- NTHI vaccine GSK2838500A (formulation 1), NTHI vaccine GSK2838501A (formulation 2), NTHI vaccine GSK2838502A (formulation 3)
- Where
- 3 sites in Belgium
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Cross-Sectional Study of COPD Prevalence Among Smokers, Ex-smokers and Never-Smokers in Almaty, Kazakhstan
The purpose of this study is to assess the prevalence of COPD among individuals aged 35 - 59 years based results of spirometry before and after bronchodilator, presence of structural changes in lungs (emphysema, inflammatory…
- Trial name
- NCT02926534
- Where
- Kazakhstan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Kazakhstan Academy of Preventive Medicine
Nicotine Addiction, E-Cig Use
Quit Smoking Study for People Who Use E-Cigarettes
The overarching aim of this proposed randomized controlled trial (RCT) is to test nicotine replacement therapy (NRT) with text message support for two smoking cessation approaches among young adult dual users of combustible…
- Conditions
- Nicotine Addiction, E-Cig Use, Quitting Smoking
- Trial name
- NCT04946825
- Testing
- Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Periodontitis
Effect of Smoking Cessation on Clinical and Microbiological Outcomes of the Non-surgical Periodontal Therapy
The aim of this prospective interventional study is to verify the efficacy of smoking cessation on clinical and microbiological outcomes of non-surgical periodontal therapy of chronic periodontitis patients.
- Trial name
- EsCAPE2 (NCT02744417)
- Testing
- Smoking cessation counseling, Non-surgical periodontal therapy, Nicotine replacement therapy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Claudio Mendes Pannuti
Smoking Cessation
Interventions for Smoking Among Persons in Recovery
Examine the efficacy of a stepped-care smoking cessation intervention for current and former smokers in chemical dependency treatment programs.
- Trial name
- INSPIRE (NCT00714896)
- Testing
- Stepped-Care, Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Periodontal Diseases, Smoking Cessation
Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease.
- Trial name
- NCT06145685
- Testing
- Minimally invasive non-surgical periodontal therapy, Conventional non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
COPD
Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease of the airway affecting approximately 10% of individuals aged 40 years or more with a smoking history.
- Trial name
- NCT01780298
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Cigarette Smoking-Related Carcinoma
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two…
- Trial name
- NCT06697496
- Testing
- QuitBot Smoking Cessation Chatbot Program, QuitBot Smoking Cessation Text Messaging Program, Survey Administration
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Substance Use Disorder (SUD)
Mobile Phone-based Smoking Cessation Program
In this online, randomized controlled trial (RCT), the participants will be randomized and allocated in 1:1 ratio to mobile phone-based intervention group or to the wait-list control group.
- Trial name
- NCT06747182
- Testing
- mobile phone-based intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Smoking Cessation, Veterans Health
Veteran Social Support for Enhancing Use of Smoking Cessation Treatment
This study is recruiting Veterans who currently smoke cigarettes and support persons who are nominated by the Veterans. The purpose of this study is to assist Veterans with smoking cessation by asking Veterans to choose a support…
- Trial name
- VAntage (NCT05868421)
- Testing
- Support Person Coaching Call, SP written materials, Written Smoking Cessation Materials
- Where
- United States
- Volunteers
- 2,376 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Smoking Cessation Intervention, Smoking Abstinence
Boosting Chinese Healthcare Service Providers' Utilization of Smoking Cessation Interventions by 'WeChat WeQuit' Program
In this single-blind, randomized trial, undertaken in China with 8-week interventions and follow-up to 52 weeks, about 2,200 providers will be randomly allocated to the intervention or control group.
- Trial name
- NCT03556774
- Testing
- 'WeChat WeQuit' smoking cessation training program
- Where
- China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease
Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
This phase II trial tests whether oral iloprost works in preventing lung cancer (chemoprevention) in former smokers. Oral iloprost has previously been shown to reduce abnormal lung cells in former smokers, suggesting a clinically…
- Conditions
- Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease, Lung Carcinoma, Stage I Lung Cancer AJCC v8
- Trial name
- NCT05411107
- Testing
- Biospecimen Collection, Bronchial Brush Biopsy, Bronchoscopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Smoking
Glucobrassicin-Brussel Sprout Effect on D10 Phe Metabolism
To determine whether glucobrassicin-rich Brussels sprouts can favorably modify the metabolism of the polycyclic aromatic hydrocarbon deuterated phenanthrene ([D10]phe) in current and former smokers
- Trial name
- NCT02999399
- Testing
- Brussel Sprouts, Deuterated Phenanthrene
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Lung Carcinoma
Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers
This clinical trial studies whether home-based respiratory muscle training (RMT) and aerobic exercise (AE) programs can be used to improve lung health in current and former cigarette smokers.
- Trial name
- NCT07553819
- Testing
- Accelerometry, Aerobic Exercise, Biospecimen Collection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Lung Diseases
Effect of the Mediterranean Diet on Lung Function in Smokers Without Previous Respiratory Disease
Several studies have shown the influence of the eating pattern on lung function. However, the benefits of the Mediterranean diet (DiMet) in preventing pulmonary dysfunction are not well known.
- Trial name
- MEDISTAR (NCT03362372)
- Testing
- Mediterranean diet counseling
- Where
- Spain
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Smoking Cessation
Determinants of Smoking Cessation Among Latinos
The goal of this study is to learn how neighborhood and individual factors affect the ability to stop smoking among Spanish-speaking Mexican American (MA) smokers who want to quit smoking.
- Trial name
- NCT01008748
- Testing
- Nicotine Replacement Therapy (NRT), Questionnaire, Counseling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking Cessation
Study on the Model of Smoking Cessation Intervention and Service Ability Improvement
This is a observation non-randomized control trial, and a follow-up study on the smoking cessation.
- Trial name
- NCT01935505
- Testing
- Consulting, Nicotine patch, Telephone intervention
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Male Infertility
Tobacco and Sperm Genome: Effects of Smoking Cessation
Tobacco is a male infertility risk factor. Many studies comparing smokers to non-smokers have shown effects on spermatogenesis and the quality of the male gamete.
- Trial name
- TABAGERM (NCT03552081)
- Testing
- Fragmented DNA evaluation in blood and semen samples
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse