Clinical trials: Former Smoker
Non Small Cell Lung Cancer
A Study of Alimta/Cisplatin/Gefitinib for Asian Non-smoking Participants With Non Small Cell Lung Cancer
The purpose of this study is to compare two different approaches to treating non-small cell lung cancer (NSCLC) in East Asian never-smoker participants.
- Trial name
- NCT01017874
- Testing
- Pemetrexed, Cisplatin, Gefitinib
- Where
- 12 sites in Hong Kong, Singapore and 3 more
- Volunteers
- 236 people
- Sponsor
- Eli Lilly and Company
COPD (Chronic Obstructive Pulmonary Disease)
RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative
The study hypothesis is that symptomatic current and former smokers with spirometric values within the normal range (post-bronchodilator FEV1/FVC≥0.70 and post-BD FVC ≥ 70% predicted will still derive symptomatic benefit from…
- Trial name
- RETHINC (NCT02867761)
- Testing
- Indacaterol/Glycopyrrolate
- Where
- 16 sites in United States
- Volunteers
- 780 people
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease (COPD)
Aclidinium/Formoterol Fixed Combination Dose Finding Study
The study seeks to determine the optimal dose of the Aclidinium/Formoterol combination for investigation in Phase III clinical trials
- Trial name
- NCT00626522
- Testing
- Aclidinium bromide and formoterol
- Where
- 9 sites in Australia, Czechia and 2 more
- Volunteers
- 808 people
- Sponsor
- AstraZeneca
Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer
Celecoxib and Erlotinib in Treating Former Smokers With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
This phase I trial is studying the side effects and best dose of celecoxib when given together with erlotinib in treating former smokers with stage IIIB, stage IV, recurrent, or progressive non-small cell lung cancer.
- Conditions
- Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00088959
- Testing
- erlotinib hydrochloride, celecoxib, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Cancer Institute (NCI)
Smoking
Effectiveness of Messages to Mobile Phone in Smoke Cessation
Smoking remains a major risk factor for chronic diseases and is a real problem for health systems. The use of emerging technologies, such as mobile phone , may have a important role in smoking cessation programs through sending…
- Trial name
- NCT01746069
- Testing
- Quit smoking combined cessation programme, health advice
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Basque Health Service
Smoking Cessation Counseling Ability, Smoking Cessation Counseling Practice
Instant Messaging Reinforcement for Smoking Cessation Counseling Training
This research aims to assess the impact of instant messaging reinforcement on the learning outcomes of smoking cessation counseling (SCC) training among master of nursing (MN) students at the University of Hong Kong.
- Trial name
- NCT06374082
- Testing
- WhatsApp message
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The University of Hong Kong
Lung Cancer
A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers
To compare the difference of a marker of cellular proliferation in all bronchial biopsy specimens of former smokers stratified by lung cancer risk, collected before and after treatment per patient between the enzastaurin and…
- Trial name
- NCT00414960
- Testing
- Enzastaurin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eli Lilly and Company
HIV Infections, Smokers
Evaluation of Cardiovascular Effects of Smoking Cessation in HIV Patients
We will conduct a sub-study of "An Innovative Telephone Intervention for HIV+ Smokers," (NCT00502827) conducted by Drs. Gritz, Vidrine, and others.
- Trial name
- NCT00918073
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bronchial Dysplasia, Tobacco Smoking
Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers
The goal of this clinical research study is to determine whether the PD-1 inhibitor (Programmed cell death protein 1) nivolumab improves premalignant bronchial dysplastic lesions in subjects that are at high risk for the…
- Conditions
- Bronchial Dysplasia, Tobacco Smoking, History of Non-Small Cell Lung Cancer, History of Head and Neck Cancer
- Trial name
- NCT03347838
- Testing
- Nivolumab
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Cessation, Smoking
Effectiveness of an Intervention in Primary Care to Promote Smoking Cessation in Pregnant Women
The purpose of this study is to evaluate the effectiveness of the behavior treatment accompanied by self-help materials in Primary health care, across the intervention of the midwifes in the pregnancy follow-up visits.
- Trial name
- GESTABAC (NCT01872156)
- Testing
- Intervention GESTABAC, Control Group
- Where
- Spain
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Tobacco Dependence, Cessation of Smoking
Effectiveness of an E-mail Tracking Intervention Among the Continued Abstinence of Tobacco Consumption
Objectives. To evaluate the effectiveness and cost effectiveness of clinical practice guide based intervention with two face-to-face visits and e-mail tracking compared to brief advice to obtain continued smoking abstinence at 6…
- Trial name
- TABATIC (NCT01494246)
- Testing
- electronic mail
- Where
- Spain
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Non-small Cell Lung Cancer
Pemetrexed (ALIMTA) and Gefitinib (IRESSA®) in Never-Smoker and Adenocarcinoma Patients With Non-Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy
Pemetrexed was known to be effective to pulmonary adenocarcinoma and gefitinib was known to be more effective to non-small cell lung cancer (NSCLC) patients with clinical characteristics such as adenocarcinoma, never smoker and…
- Trial name
- NCT01066195
- Testing
- iressa, alimta
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Samsung Medical Center
Substance Use Disorder (SUD)
Mobile Phone-based Smoking Cessation Program
In this online, randomized controlled trial (RCT), the participants will be randomized and allocated in 1:1 ratio to mobile phone-based intervention group or to the wait-list control group.
- Trial name
- NCT06747182
- Testing
- mobile phone-based intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Smoking
Glucobrassicin-Brussel Sprout Effect on D10 Phe Metabolism
To determine whether glucobrassicin-rich Brussels sprouts can favorably modify the metabolism of the polycyclic aromatic hydrocarbon deuterated phenanthrene ([D10]phe) in current and former smokers
- Trial name
- NCT02999399
- Testing
- Brussel Sprouts, Deuterated Phenanthrene
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Tobacco Use
Smartphone Application Smoking Cessation Study
The purpose of the study is to determine if using the smartphone application quitSTART can help people quit smoking and to understand how use of specific smartphone application features when trying to quit smoking is associated…
- Trial name
- NCT04623736
- Testing
- quitSTART
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking Cessation, Pregnancy Related
Organization of Smoking Cessation in Pregnant Women With the Implementation of the 5A Strategy in New Aquitaine.
The investigators are conducting a pragmatic cluster randomized trial in stepped-wedge of which objectives are to evaluate the effectiveness and the conditions of effectiveness of an organizational strategy for smoking cessation…
- Trial name
- 5A-QUIT-N (NCT05355012)
- Testing
- 5A organizational innovation
- Where
- France
- Volunteers
- 4,505 people
- Sponsor
- University Hospital, Bordeaux
Precancerous Conditions
Phase I/II Study of Chemoprevention With EGFR and COX-2 Inhibitor
Evaluate effect on cells and patient response to study medications, assess side effects of these medications, and evaluate chemicals in cells that may tell how the drug works, before, and after receiving the study medications.
- Trial name
- NCT00314262
- Testing
- Erlotinib & Celecoxib
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Emory University
Smoking Cessation Intervention, Smoking Abstinence
Boosting Chinese Healthcare Service Providers' Utilization of Smoking Cessation Interventions by 'WeChat WeQuit' Program
In this single-blind, randomized trial, undertaken in China with 8-week interventions and follow-up to 52 weeks, about 2,200 providers will be randomly allocated to the intervention or control group.
- Trial name
- NCT03556774
- Testing
- 'WeChat WeQuit' smoking cessation training program
- Where
- China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Lung Cancer, Precancerous Condition
Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of Polyphenon E, a substance found in green tea, may keep cancer from forming in current or former smokers with bronchial dysplasia.
- Conditions
- Lung Cancer, Precancerous Condition, Tobacco Use Disorder
- Trial name
- NCT00611650
- Testing
- defined green tea catechin extract
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- British Columbia Cancer Agency
Smoking Cessation, Veterans Health
Veteran Social Support for Enhancing Use of Smoking Cessation Treatment
This study is recruiting Veterans who currently smoke cigarettes and support persons who are nominated by the Veterans. The purpose of this study is to assist Veterans with smoking cessation by asking Veterans to choose a support…
- Trial name
- VAntage (NCT05868421)
- Testing
- Support Person Coaching Call, SP written materials, Written Smoking Cessation Materials
- Where
- United States
- Volunteers
- 2,376 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development