Clinical trials: Flutter, Atrial
Atrial Flutter
The VERISMART Trial
Catheter ablation is now routinely used in the management of heart rhythm disorders. One of the problems with the approach is that it has not been possible to determine whether the ablation catheter is in direct contact with the…
- Trial name
- VERISMART (NCT02490033)
- Testing
- Ablation Catheter
- Where
- United Kingdom
- Volunteers
- 133 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Atrial Fibrillation (AF)
Efficacy and Safety of Pulsed Field Ablation in Refractory Mitral Isthmus-dependent Atrial Flutter: Pulsed Field Ablation Vs. Radiofrequency Ablation: a Preliminary Randomized Controlled Study
Efficacy and safety of pulsed field ablation in refractory mitral isthmus-dependent atrial flutter: pulsed field ablation vs. radiofrequency ablation: a preliminary randomized controlled study
- Trial name
- NCT06850064
- Testing
- Pulse Field Ablation (PFA), Radiofrequency ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation, Atrial Flutter
Atrial Fibrillation/Flutter Outcome Risk Determination
It is our hypotheses that 1) readily available Emergency Department data can be utilized in an Atrial Fibrillation clinical prediction rule to identify those patients at low or high risk for adverse outcomes; 2) Assigned risk can…
- Trial name
- AFFORD (NCT01138644)
- Where
- United States
- Volunteers
- 519 people
- Sponsor
- Vanderbilt University
Cavotricuspid Isthmus Dependent Right Atrial Flutter
LINEAR II - LME-159 Evaluation of a Multi-Electrode Linear Type Ablation Catheter
The Linear II study is a prospective, single center, non-randomized, interventional feasibility study with the purpose of assessing acute safety of the Multi-Electrode Linear Type Ablation Catheter and the performance of the…
- Trial name
- NCT02257060
- Testing
- Endocardial Ablation
- Volunteers
- 12 people
- Sponsor
- Biosense Webster, Inc.
Arrhythmias, Cardiac, Atrial Fibrillation
Physician Acceptance of the NeuTrace System for Cardiac Electroanatomic Mapping
The trial is a prospective, non-randomized, single-arm feasibility trial to evaluate physician acceptance of the NeuTrace System v1.0 for cardiac electroanatomic mapping.
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05214170
- Testing
- Electroanatomic mapping with the NeuTrace System
- Where
- Lithuania
- Volunteers
- 20 people
- Sponsor
- NeuTrace, Inc.
Paroxysmal Atrial Fibrillation (PAF), Atrial Flutter
Home Monitor for AA Burden Detection IIT in TWN
Primary Endpoint: Early detection rate in Atrial Arrhythmia (AA) burden Data transmission success rate for overall number of atrial burden collection during the monitoring period Secondary Endpoints: Atrial burden occurrence at…
- Trial name
- FF108 (NCT07572279)
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Paroxysmal Atrial Fibrillation
Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation
It has been demonstrated that successful cavotricuspid isthmus ablation may be effective in preventing paroxysmal atrial fibrillation. However, the effectiveness of only isthmus ablation on atrial fibrillation itself is unclear.
- Trial name
- NCT02031705
- Testing
- cavotricuspid isthmus ablation, control group
- Where
- South Korea
- Volunteers
- 366 people
- Sponsor
- Yong Seog Oh
Atrial Fibrillation, Atrial Flutter
Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control
Atrial Fibrillation and atrial flutter (AF/FL) is the usually irregular beating of the heart and is a rapidly growing cause of hospitalization.
- Trial name
- NCT02025465
- Testing
- Metoprolol, Diltiazem
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- CAMC Health System
Atrial Flutter
Atrial Flutter Ablation in a Real World Population
The "LEONARDO" study is a non-randomized, multicenter, prospective study in which consecutive patients indicated for Atrial Flutter isthmus-dependent (AFL) ablation will be enrolled.
- Trial name
- NCT02591875
- Where
- 4 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera Pugliese Ciaccio
Cavotricuspid Isthmus Dependent Atrial Flutter
Pulsed Field Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter Cohort Study
Pulsed field ablation (PFA) has been demonstrated to be safe and effective in achieving pulmonary vein isolation in patients with atrial fibrillation (AF). Coexisting atrial flutter is common in patients with AF.
- Trial name
- NCT07012460
- Testing
- CTI ablation
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Atrial Fibrillation, Atrial Flutter
Comparison of ATI-5923, a Novel Vitamin K Antagonist, With Warfarin in Patients Requiring Chronic Anticoagulation
The purpose of this research study is to test an experimental drug ATI-5923 vs Coumadin. The study is intended to demonstrate ATI-5923 is superior to Coumadin for keeping INR values in the desired therapeutic range.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Venous Thromboembolic Disease, Myocardial Infarction
- Trial name
- EmbraceAC (NCT00691470)
- Testing
- ATI-5923, Coumadin (warfarin)
- Where
- 41 sites in United States
- Volunteers
- 600 people
- Sponsor
- ARYx Therapeutics
Atrial Fibrillation, Perimitral Flutter
Ablation of Perimitral Flutter Following Catheter Ablation of Atrial Fibrillation: Impact on Outcomes
This prospective, randomized study aims to compare the impact of ablation of perimitral flutter only versus cardioversion and repeat isolation of pulmonary veins with ablation of additional triggers, on procedure outcome.
- Trial name
- PROPOSE (NCT01173796)
- Testing
- catheter ablation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation, Atrial Flutter
Evaluate the Pharmacokinetics and Safety of MK-4448 in Participants With Nonvalvular Atrial Fibrillation or Atrial Flutter
The primary purpose of this study is to optimize drug exposure in the target population.
- Trial name
- NCT01229254
- Testing
- Amiodarone, Betrixaban 60 mg, Betrixaban 90 mg
- Volunteers
- 189 people
- Sponsor
- Portola Pharmaceuticals
Atrial Flutter
Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter
The primary objective is to provide additional corroborative safety and efficacy data for the Navistar Thermocool catheter for the treatment of subjects with typical atrial flutter (AFL).
- Trial name
- NCT00318565
- Testing
- RF energy delivery for treatment of Typical Atrial flutter
- Where
- 23 sites in United States
- Volunteers
- 291 people
- Sponsor
- Biosense Webster, Inc.
Current or Recent History of Atrial Fibrillation
Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
This study is being done to compare the effects of bucindolol hydrochloride (bucindolol) to metoprolol succinate (Toprol-XL) on the recurrence of symptomatic atrial fibrillation/atrial flutter in patients with heart failure who…
- Trial name
- GENETIC-AF (NCT01970501)
- Testing
- bucindolol hydrochloride, metoprolol succinate
- Where
- 97 sites in United States, Canada and 4 more
- Volunteers
- 267 people
- Sponsor
- ARCA Biopharma, Inc.
Atrial Fibrillation and Flutter, Atrial Arrhythmia
Development of a New Impedance Mapping System for Ablation of Atrial Arrhythmias in Patients
Precise identification of the atrial fibrosis is essential for successful catheter ablation of atrial arrhythmias in patients with atrial fibrillation.
- Conditions
- Atrial Fibrillation and Flutter, Atrial Arrhythmia, Atrial Fibrillation Recurrent
- Trial name
- NCT05159180
- Testing
- cardioz mapping
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Atrial Flutter
A Randomized Trial of Contact Force in Atrial Flutter Ablation
A clinical randomized trial to evaluate if CF guided Radio Frequency Ablation (RFA) to a specific of LSI in atrial flutter i superior to standard RFA.
- Trial name
- CF-CTIA (NCT02917538)
- Testing
- RFA
- Where
- Denmark
- Volunteers
- 156 people
- Sponsor
- Aarhus University Hospital Skejby
Atrial Fibrillation, Atrial Flutter
PREdicting Atrial Fibrillation or Flutter
The purpose of this study is to determine, through continuous monitoring with a cardiac monitoring device placed under the skin, the incidence of atrial fibrillation or flutter (AF).
- Trial name
- PREDATE-AF (NCT01851902)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Keesler Air Force Base Medical Center
Atrial Flutter
Radiofrequency Ablation Plus Botulinum Toxin Injection Versus Radiofrequency Ablation Only in Patients With Atrial Flutter
The aim of this randomized study was to assess the effectiveness of endomyocardial botulinum toxin injection for preventing post-procedural atrial fibrillation in patients undergoing the radiofrequency ablation of atrial flutter.
- Trial name
- NCT02002962
- Testing
- radiofrequency ablation, Botulinum Toxin Type A injection
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter
Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy
The purpose of this pragmatic study is to evaluate the safety, performance and effectiveness of the VARIPULSE catheter technology used in combination with the TRUPULSE™ Generator, and the compatible EAM system (Carto 3D) to treat…
- Conditions
- Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical
- Trial name
- VIRTUE (NCT06056557)
- Testing
- VARIPULSE™ catheter ablation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Vivek Reddy