Clinical trials: Flare Up, Symptom
Chronic Obstructive Pulmonary Diseases, COPD
Effect of IMT in Patients After Acute Exacerbations of COPD
The goal of this clinical trial is to test whether home-based inspiratory muscle training can reduce hospital readmissions and death in patients recovering from a severe acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- Chronic Obstructive Pulmonary Diseases, COPD, Symptom Exacerbation
- Trial name
- IN-SPIRED (NCT07213128)
- Testing
- Training
- Where
- 12 sites in Belgium
- Volunteers
- 358 people
- Sponsor
- KU Leuven
Postoperative Pain, Flare Up, Symptom
Effect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment
The primary objective of this randomized clinical trial is to evaluate and compare the effectiveness of two natural, herbal-based intracanal medications-Propolis and Green Tea Polyphenolics (EGCG)-against the conventional Calcium…
- Conditions
- Postoperative Pain, Flare Up, Symptom, Flare up
- Trial name
- NCT07578311
- Testing
- Calcium hydroxide, Propolis Extract, Green Tea Polyphenolics (EGCG)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Juvenile Idiopathic Arthritis, Flare Up, Symptom
Biomarkers in Pediatric Inflammatory Rheumatic Diseases
A prospective study is proposed to serially determine new biomarkers: Calprotectin and Serum Amyloid Protein, alongside 'conventional' biomarkers: CRP and ESR, to help evaluate their utility in routine clinical practice
- Trial name
- BIRPED (NCT07356804)
- Testing
- Calprotectine
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postoperative Pain, Flare up
Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence
This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical…
- Conditions
- Postoperative Pain, Flare up, Flare Up, Symptom
- Trial name
- NCT07084194
- Testing
- Chitosan Nanoparticles Irrigant, aloe vera nanoparticles irrigant, Diode Laser Activation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Minia University
Postoperative Pain, Flare Up, Symptom
Postoperative Pain and Flare-Up Rates in Diabetic Type II Patients Following The Use of Bioceramic Intracanal Medication
The goal of this randomized clinical trial is to evaluate the Postoperative Pain and Flare-Up incidence following the use of Bio-Ceramic Based Intra-Canal Medication in Diabetic type II Patients compared to the Calcium Hydroxide…
- Conditions
- Postoperative Pain, Flare Up, Symptom, Flare up, Diabete Type 2
- Trial name
- NCT07071675
- Testing
- Calcium Hydroxide Intracanal medication, bioceramic based intracanal medication
- Volunteers
- 56 people
- Sponsor
- Minia University
Cystic Fibrosis, Lung Inflammation
TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era
Progressive destruction of the lungs is the main cause of shortened life expectancy in people with cystic fibrosis (pwCF). Inflammation and respiratory infections play a key role in CF lung disease.
- Conditions
- Cystic Fibrosis, Lung Inflammation, Lung Infection, Lung Disease; Cystic
- Trial name
- TERRIFIC-MILE (NCT05752019)
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Periapical Diseases, Periapical Periodontitis
Postoperative Pain After Conservative Root Canal Preparation
The goal of this clinical trial is to compare the pain experienced by healthy participants after root canal treatment with small versus large root canal sizes. The main questions it aims to answer are: 1.
- Conditions
- Periapical Diseases, Periapical Periodontitis, Postoperative Pain, Pulp Necroses
- Trial name
- NCT06545773
- Testing
- Root Canal Treatment with ProTaper Next Nickel-Titanium File (PTN), Root Canal Treatment withTruNatomy Nickel-Titanium File (TN)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Psoriatic Arthritis, Flare Up, Symptom
PsA Digital Phenotyping and Inflammation Drivers Study
The goal of this observational study is to develop and internally validate a machine learning model for detecting flare using a digital biomarker and a machine learning model for predicting flare, in patients with psoriatic…
- Conditions
- Psoriatic Arthritis, Flare Up, Symptom, Psoriatic Arthritis Aggravated
- Trial name
- PDPID (NCT06347237)
- Volunteers
- 600 people
- Sponsor
- Jolanda Luime
Ulcerative Colitis, Flare Up, Symptom
Effectiveness of Golimumab in Patients With Ulcerative Colitis: Results of a Real-life Study in Switzerland
TNF inhibitors have improved treatment options for patients with inflammatory bowel disease (IBD) and three TNF inhibitors, infliximab, adalimumab and golimumab are available for treatment of ulcerative colitis in Switzerland.
- Trial name
- NCT05405465
- Testing
- Exposure to golimumab
- Where
- Switzerland
- Volunteers
- 103 people
- Sponsor
- University of Zurich
Ulcerative Colitis, Flare Up, Symptom
Real-world Data Regarding Treatment of Ulcerative Colitis Patients With Golimumab
TNF inhibitors have improved treatment options for patients with inflammatory bowel disease (IBD) and three TNF inhibitors, infliximab, adalimumab and golimumab are available for treatment of ulcerative colitis in Switzerland.
- Trial name
- NCT03394586
- Testing
- Exposure to golimumab
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich