Clinical trials: First Aid, open to volunteers
Advanced Heart Failure
CorWave LVAS FIH Study
The study is a prospective, multi-center, non-randomized trial to evaluate the safety and effectiveness of the CorWave LVAS for the treatment of advanced heart failure patients.
- Trial name
- NCT06907017
- Testing
- LVAS
- Where
- 3 sites in Australia, Kazakhstan
- Volunteers
- 20 people
- Sponsor
- CorWave
Waitlist Control, Experimental
Effects of Youth Mental Health First Aid (YMHFA) on South Asian American Adults Working With South Asian American Youth
This study aims to adapt the Youth Mental Health First Aid training to better meet the needs of South Asian American adults who support South Asian American youth. Focus groups will help identify what changes are needed.
- Trial name
- NCT07135479
- Testing
- Youth Mental Health First Aid
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Rectum Cancer
Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery
The aim of the study is to evaluate the technical feasibility and applicability of a surgical assistance system based on image recognition algorithms in a first-in-human pilot study.
- Trial name
- CoBot2 (NCT05652361)
- Testing
- Additional visualisation of surgical assistance during surgery
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Technische Universität Dresden
Coronary Artery Disease
First in Human Trial of R-Star: A Novel Robotic System for Minimally Invasive Coronary Artery Procedures.
The goal of this clinical trial is to learn if the R-Star robotic system can be used safely and effectively to perform percutaneous coronary intervention (PCI) in adults with coronary artery disease who are scheduled for an…
- Trial name
- R-STAR-FIH (NCT07146204)
- Testing
- Robotic-assisted percutaneous coronary intervention
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Robocath
Primary PCI, ST-elevation Myocardial Infarction (STEMI)
Impact of Pre-Hospital Heparin Loading in STEMI Patients for Primary PCI: The HELP-PCI-2 Trial
This randomized, multicenter, prospective trial will enroll 6,294 participants in approximately 80 centers. STEMI patients with onset time within 12 hours and scheduled for primary PCI will be randomly assigned to two groups in a…
- Trial name
- HELP-PCI-2 (NCT07361783)
- Testing
- Unfractionated heparin treatment
- Where
- China
- Volunteers
- 6,294 people
- Sponsor
- Chen Jing
Hearing Loss
WhatsApp AI Support vs Paper Support for First-Time Hearing Aid Users
The purpose of this study is to advance hearing care in low- and middle-income countries (LMICs) through the rigorous evaluation and optimization of innovative interventions and technologies.
- Trial name
- NCT07690670
- Testing
- Go Ultra Hearing Aids, WhatsApp-delivered AI-enabled support, Paper-Based Support Programme
- Where
- 2 sites in South Africa
- Volunteers
- 66 people
- Sponsor
- University of Pretoria
Venous Thromboembolism
Filter Initial & Long Term Evaluation After Placement and Retrieval Registry
A prospective data registry for all patients who undergo IVC (Inferior Vena Cava) filter placement or retrieval at Stanford. Potential enrollees will already be undergoing the procedure.
- Trial name
- FILTER (NCT01158482)
- Testing
- IVC Filter Placement or Retrieval
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
Colo-rectal Cancer, Shared Decision Making
Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49
The primary objective of this study was to evaluate the impact of a constructed shared decision (SDM) intervention (offering an option between colonoscopy and immunochemical collapsible occult blood testing (fecal immunochemical…
- Conditions
- Colo-rectal Cancer, Shared Decision Making, Patient Decision Aid
- Trial name
- NCT07503847
- Testing
- Colonoscopy, Shared Decision-Making
- Where
- Taiwan
- Volunteers
- 2,286 people
- Sponsor
- National Taiwan University Hospital
The Aim is to Strengthen Disaster Preparedness Knowledge and Skills Through Peer Interaction
The Effect of a Peer-Based Instructional Disaster Education Program on Disaster Preparedness Beliefs and Disaster Attitudes of First Aid and Emergency Program Students
Objective: Continuous education and training in disaster preparedness is critically important for first aid and emergency program students, who will be the future healthcare professionals, especially in the pre-hospital setting.
- Trial name
- disaster (NCT07564999)
- Testing
- peer-supported disaster preparedness training, Rutin
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Post-Traumatic Stress Disorder, Adjustment Disorders
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
The purpose of this study is to assess the safety and efficacy of MDMA-Assisted Therapy on Frontline Health Care Workers and First Responders suffering from symptoms of Post-Traumatic Stress.
- Trial name
- NCT05455996
- Testing
- MDMA
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nautilus Sanctuary
Airway Management
First Attempt Success in Tracheal Intubation Through Supraglottic Airway Devices Without Fiberoptic Guidance
This randomized controlled trial aims to compare the first-attempt success rate of tracheal intubation through supraglottic airway devices using a conventional intubating supraglottic airway device versus a video-assisted…
- Trial name
- NCT07704723
- Testing
- Video-assisted supraglottic airway device, Conventional intubating supraglottic airway device
- Volunteers
- 204 people
- Sponsor
- Seoul National University Hospital
Hearing Loss, Hearing Aids
New Hearing Aid Users and Their Social Participation
Does first-ever hearing aid fitting change social participation? Using a mixed methods approach made up of audiological assessments (hearing test and examination of the ear canal and eardrum), questionnaires, semi-structured…
- Conditions
- Hearing Loss, Hearing Aids, Social Participation
- Trial name
- NCT07866586
- Testing
- Observation
- Volunteers
- 32 people
- Sponsor
- University of Nottingham
Heart Failure
A First-in-Human Study to Evaluate the Safety and Efficacy of Left Ventricular Assist Device Combined With Exosome Therapy for Patients With Heart Failure（RESTORATION）
A single-center, randomized, double-blind, placebo-controlled, dose-escalation clinical study to evaluate the safety and tolerability of intravenous infusion of different doses of the investigational exosome preparation in heart…
- Trial name
- NCT07883317
- Testing
- Exosome Preparation
- Volunteers
- 24 people
- Sponsor
- Yining Yang
Post Traumatic Stress Disorder
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers…
- Trial name
- NCT05751473
- Testing
- Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
- Where
- 14 sites in United States
- Volunteers
- 410 people
- Sponsor
- University of Michigan
Lower Molar Requiring Extraction
Effect of Placing the Implant Crown on the Implant on the Same Day as the Implant vs. 4 Weeks Later.
In this study, participants with one lower first molar that require removal and replacement using dental implants will be enrolled.
- Trial name
- NCT04319042
- Testing
- Immediate Loading, Early Loading
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Bern
First Aid Training, Health Education
Effect of Simulation-Based First Aid and Basic Health Training on Parents of Children With Special Need
Childhood accidents and sudden health emergencies are significant public health concerns that may lead to severe injury or death.
- Trial name
- NCT07798102
- Testing
- 5E Model-Based Simulation Training Group, Standard Training Group
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Lumbar Puncture
Ultrasound-assisted vs Palpation-guided Lumbar Punctures
The goal of this randomized clinical trial is to determine whether ultrasound-assisted lumbar puncture improves first-needle insertion success compared with the standard palpation technique in adults undergoing a clinically…
- Trial name
- NCT07824284
- Testing
- Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- The Cooper Health System
Postoperative Sleep Disturbance
Dynamic Prediction of Sleep Protection Demand on the First Postoperative Night and Its Influence on Ward Process After Thoracoscopic Lobectomy or Segmentectomy
This study combines retrospective data analysis with a single-center prospective non-interventional cohort study to understand postoperative sleep disturbance on the first night after video-assisted thoracoscopic (VATS) lobectomy…
- Trial name
- NCT07716085
- Testing
- Video-assisted thoracoscopic (VATS) lobectomy or segmentectomy
- Volunteers
- 400 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Snake Bites, Snakebite
Analysis of the Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.
Snake bite affects thousands of Australians every year, but few die as a result due to high quality first aid and timely medical care.
- Conditions
- Snake Bites, Snakebite, Snake Envenomation, Snake Bite
- Trial name
- NCT07261982
- Testing
- Pressure bandage immobilisation first aid, Pressure pad first aid, Control - no first aid
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Townsville University Hospital
Healthy Subjects (HS)
Evaluation of the Effectiveness of Teen Mental Health First Aid in Secondary School Students in Hong Kong
Mental health problems in adolescents are on the rise worldwide especially after COVID -19 pandemic. Early detection and intervention should help to reduce the adverse impact of the mental illness on the adolescent.
- Trial name
- tMHFA-HK (NCT07195890)
- Testing
- A course of teen Mental Health First Aid to be provided to participants
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TN Foo Centre for Positive Mental Health