Clinical trials: Finger Joint
Erosive Osteo-Arthritis
Study to Evaluate the Efficacy of Adalimumab in Patients With Erosive Osteoarthritis of the Interphalangeal Finger Joints
Patients will be randomized into two groups (1/1) during one year: 40 mg adalimumab subcutaneously (sc) every other week placebo The effect on x-rays and clinical parameters will be evaluated.
- Trial name
- NCT00296894
- Testing
- Adalimumab (40 mg sc every other week)
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Proximal Interphalangeal Joint Stiffness
Pilot Study on The Effectiveness of Relative Motion Orthosis in Finger Motion
The purpose of this feasibility pilot study is to determine the effectiveness of Relative Motion Orthosis (RMO) in regaining finger range of motion compared to standard care in patients diagnosed with Proximal Interphalangeal…
- Trial name
- NCT06646029
- Testing
- RMO flexion orthosis (splint), Standard of care
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- NYU Langone Health
Patient Specific Computational Modeling
Development of a Musculoskeletal Model of the PIP Joint
The proximal interphalangeal (PIP) joint is the second joint in the finger from the finger tip. The outcome following replacement surgery of this joint is considered unsatisfactory.
- Trial name
- NCT03094962
- Testing
- Motion capture, MR scan, CT scan
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Osteoarthritis, Osteoarthritis Finger
Effects of Using Custom Photobiomodulation Therapy for the Treatment of Osteoarthritis of the Fingers and Rhizarthrosis
Osteoarthrosis (OA), a multifactorial degenerative process, is responsible for joint pain and functional limitation. In the hand, more specifically in the proximal and distal interphalangeal joints of the fingers, it is one of…
- Conditions
- Osteoarthritis, Osteoarthritis Finger, Osteoarthritis Hand, Osteoarthritis Both Hands
- Trial name
- NCT05041231
- Testing
- Photobiomodulation therapy (PBT)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Vita Care
Osteoarthritis
A Soft Robotics Approach Towards Finger Joint Deformities in Rheumatic Diseases
The study is to investigate the effect of a soft robotic glove approach providing continuous passive motion of fingers (flexion and extension) on degenerative arthritis patients.
- Trial name
- NCT03326817
- Testing
- Control Group, Soft Robotic Glove Group
- Where
- Singapore
- Volunteers
- 8 people
- Sponsor
- National University Hospital, Singapore
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Arthrosis, Osteoarthrosis
HUD: PIP Joint Implant
This surgery involves the use of a finger joint replacement device for treatment of patients with certain kinds of arthritis (osteo - arthritis or post traumatic arthritis) and who expect to place their hands in heavy loading…
- Trial name
- NCT02434913
- Testing
- SR PIP Implant System
- Sponsor
- The Hawkins Foundation
Rheumatoid Arthritis, Healthy Control
Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.
- Trial name
- NCT07360496
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Osteoarthritis Finger, Surgery
Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint.
- Trial name
- NCT05980793
- Testing
- PIP joint denervation, Patient education plus exercise
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Osteoarthritis
An RSA and DEXA Study on Migration of Proximal Interphalangeal (PIP) Joint Prostheses of the Hand
The purpose of this study is to compare the early migration and the periprosthetic bone changes of cemented versus non-cemented interphalangeal implants using Roentgen stereophotogrammetric analysis and dual energy x-ray…
- Trial name
- NCT00175188
- Testing
- Avanta (PIP joint implant with a titanium porous coating)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Proximal Interphalangeal Joint Fracture
Evaluation of Suzuki Frame Fixation in Comminuted Fractures of the Proximal Interphalangeal Joint.
This prospective randomized controlled trial aims to evaluate the functional and radiological outcomes of using the Suzuki frame for treating comminuted intra-articular fractures of the proximal interphalangeal (PIP) joint.
- Trial name
- NCT07714356
- Testing
- Suzuki Frame, Standard Conventional Treatment.
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Yehia Mohamed
Healthy
Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study
The purpose of the study is to gain a better understanding of mechanoreceptors in the PIP joint ligamento-muscular reflexes and their role is.
- Trial name
- NCT01456871
- Testing
- Guided insertion of electrodes, Electromyographic (EMG) recording
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Rheumatoid Arthritis, Bone Density
Effect of Baricitinib Treatment on Peripheral Bone in RA
Patients with Rheumatoid Arthritis (RA) suffer systemic and peripheral bone loss. In this study we aim to test the efficacy of in-label treatment with Baricitinib on the volumetric bone mineral density in patients with RA over 52…
- Conditions
- Rheumatoid Arthritis, Bone Density, Finger Joints
- Trial name
- BAREBONE (NCT03701789)
- Testing
- Baricitinib
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hand Osteoarthritis
RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
This is a randomized, double blind placebo controlled one-site proof-of-concept study in subjects with erosive osteoarthritis (OA) of interphalangeal (IP) finger joints.
- Trial name
- NCT02771860
- Testing
- denosumab, Calcium/Vit D supplementation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Trigger Finger, Stenosing Tenosynovitis
Low-Level Laser Therapy in the Treatment of Trigger Finger
Trigger finger, also known as stenosing tenosynovitis, is one of the most common disorders affecting the hand. Its lifetime prevalence is 2-3%.
- Conditions
- Trigger Finger, Stenosing Tenosynovitis, Trigger Digit
- Trial name
- NCT07753460
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Dokuz Eylul University
Proximal Interphalangeal Joint Stiffness
Effectiveness of Exercise Relative Motion Orthoses for Limited Finger Joint Motion
This randomized controlled trial investigates the effectiveness of two exercise orthosis designs-the Relative Motion Flexion (RMF) and Relative Motion Extension (RME) orthoses-for improving motion in patients with proximal…
- Trial name
- Exercise RM-O (NCT06985459)
- Testing
- PIP extension deficit treated with an exercise RMF orthosis, PIP flexion deficits treated with an exercise RME orthosis
- Where
- Switzerland
- Volunteers
- 148 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hand Fractures
Repair of Extra-articular Fractures of the Metacarpals and First Phalanges of the Long Fingers
The goal of this randomized controlled trial is to compare the effectiveness, complications, and cost-effectiveness of three surgical techniques (intramedullary screw fixation, locked plating, and percutaneous pinning) for…
- Trial name
- FinXger (NCT07186829)
- Testing
- Percutaneous pinning, Locked plate, Intramedullary screw
- Where
- France
- Volunteers
- 111 people
- Sponsor
- University Hospital, Montpellier
Finger Joint, Arthroplasty
Silicone Arthroplasty vs. Arthrodesis in the Distal Interphalangeal Joint
The operational and favored standard therapy for the treatment of osteoarthritis in the distal interphalangeal joint is the arthrodesis, in which a titanium screw is used.
- Conditions
- Finger Joint, Arthroplasty, Replacement
- Trial name
- NCT01740999
- Testing
- silicone arthroplasty, arthrodesis
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- Schulthess Klinik
Trigger Finger, Stenosing Tenosynovitis
Comparing Relative Motion Splint and Metacarpophalangeal Joint Blocking Splint for Trigger Finger
The purpose of this study is to compare the effectiveness of relative motion splint and metacarpophalangeal joint blocking splints in terms of sign and symptoms, hand function, occupational performance, and perception of splint…
- Trial name
- NCT05763017
- Testing
- Relative Motion Splint, Metacarpophalangeal Joint Blocking Splint
- Where
- Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia