Clinical trials: Fertility Issues
Infertility
Does Endometrial Injury Improve Intrauterine Insemination Outcome?
The investigator suggests that local endometrial injury using pipelle catheter performed in the follicular phase (cycle day 5, 6 or 7) of the stimulation cycle may improve the pregnancy rates among patients undergoing…
- Trial name
- NCT02542280
- Testing
- endometrial injury., intrauterine insemination, ovarian stimulation
- Volunteers
- 360 people
- Sponsor
- Ain Shams Maternity Hospital
SARS CoV-2
Safety and Feasibility of Amniotic Fluid as a Treatment for COVID-19 Patients
The purpose of this study is to explore the effectiveness of processed human amniotic fluid as a treatment for COVID-19.
- Trial name
- NCT04497389
- Testing
- Human Amniotic Fluid
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Ovulation Induction
A Phase 2 Trial to Evaluate if Corifollitropin Alfa (Org 36286), Followed by a Low Daily Dose of hCG or Recombinant FSH Can Induce Monofollicular Growth in Women With WHO Group II Anovulatory Infertility (P05693)
The primary objective of this trial is to evaluate whether a corifollitropin alfa (Org 36286) regimen applying a single or repeated dose of corifollitropin alfa followed by a low daily dose of Human Chorion Gonadotropin (hCG) or…
- Trial name
- NCT00697255
- Testing
- corifollitropin alfa, recombinant Follicle Stimulating Hormone (recFSH), human Chorion Gonadotropin (hCG)
- Volunteers
- 8 people
- Sponsor
- Organon and Co
Infertility
Antimullerian Hormone Versus Antral Follicle Count for Determination of Gonadotrophin Dosing in IVF
This is a prospective randomized trial to compare the use of AFC and serum AMH as the basis for gonadotrophin dosing in in-vitro fertilization treatment.
- Trial name
- NCT02739269
- Testing
- Serum AMH measurement, AFC measurement
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Endometriosis
BGS649 Monotherapy in Moderate to Severe Endometriosis Patients
This study will assess the safety and tolerability of BGS649 in women with moderate to severe endometriosis.
- Trial name
- NCT01190475
- Testing
- Active treatment with a high dose of BGS649, Active treatment with a low dose of BGS649
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mereo BioPharma
Dry Eye Disease
Phase II Study of SHJ002 Sterile Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
The purpose of this study is to measure efficacy and safety with SHJ002 sterile ophthalmic solution compared to vehicle in participants with Dry Eye Disease (DED).
- Trial name
- NCT05486728
- Testing
- SHJ002/Vehicle
- Where
- 4 sites in Australia, Taiwan and 1 more
- Volunteers
- 85 people
- Sponsor
- Dreamhawk Vision Biotech, Inc.
Infertility
Rekovelle PK Trial in Chinese Women
FE 999049 is a gonadotropin preparation containing recombinant human follicle stimulating hormone (rhFSH) under development by Ferring Pharmaceuticals.
- Trial name
- NCT04150861
- Testing
- Follitropin Delta
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Infertility, Female
Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility
A two-arm, multicenter, prospective, randomized clinical trial of a lifestyle modification program with tracked increased physical activity and weight loss (intensive) compared to recommendations to tracking of increased physical…
- Trial name
- FIT-PLESE (NCT02432209)
- Testing
- Caloric Restriction, Orlistat, Moderate physical activity
- Where
- 10 sites in United States
- Volunteers
- 379 people
- Sponsor
- Yale University
Infertility
Multi-centre Study to Compare Efficacy and Safety of AFOLIA and Gonal-f in Women for Assisted Reproductive Treatment
Ther purpose of this study is to show equivalence between AFOLIA and Gonal-f® with regard to the number of oocytes retrieved in women for assisted reproductive treatment.
- Trial name
- NCT01121666
- Testing
- Follitropin alfa
- Where
- 16 sites in Austria, Denmark and 4 more
- Volunteers
- 460 people
- Sponsor
- Finox AG
Infertility
The Evaluation of Recombinant LH Supplementation in Patients With Suboptimal Response to Recombinant FSH Undergoing ICSI
The investigators aimed to evaluate patients who had In-vitro fertilization treatment and who had COH (controlled ovarian hyperstimulation) cycles applying long protocol with GnRH (gonadotropin-releasing hormone) analogue with…
- Trial name
- LH (NCT02108223)
- Testing
- fix dose r-FSH (Gonal-f), r-LH supplementation, r-FSH (Gonal-f)
- Volunteers
- 137 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital