Clinical trials: Fertility
Breast Cancer, Infertility
RCT of Fixed vs Titrated Letrozole in Breast Cancer Patient Undergoing IVF
The purpose of this study is to compare two different ways to administer Letrozole to determine their effectiveness in blocking estrogen production during ovarian stimulation in patients with breast cancer prior to…
- Trial name
- NCT01035099
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Weill Medical College of Cornell University
Fertility
Validation Study Using a Time-lapse Morphometry MIRI Imaging Incubator
The purpose of this study is to evaluate the safety and efficacy of the MIRI-TL time-lapse incubator and CultureCoin dish compared to standard big-box incubators and standard culture dishes used for embryo culture.
- Trial name
- TiMMI (NCT02852356)
- Testing
- MIRI-TL Incubator
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Infertility, Female
Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)
This a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer.
- Trial name
- NCT01202656
- Testing
- G-CSF, Saline
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Male Infertility, Obesity
Investigating the Physiological Effects of Weight Loss on Male Fertility
The purpose of this study is to determine the physiological effects of weight loss on seminal parameters in male participants with reduced reproductive capacity.
- Conditions
- Male Infertility, Obesity, Weight Loss
- Trial name
- NCT03553927
- Testing
- Low Energy Diet, NHS advice on healthy eating
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Fertility
Dysregulation of FSH in Obesity: Functional and Statistical Analysis
Excess maternal weight, especially obesity, influences almost every aspect of fertility, from conception to problems during pregnancy.
- Trial name
- NCT02478775
- Testing
- Degarelix (GnRH antagonist), recombinant FSH, Cetrorelix
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Evaluation Studies, Implementation Research
Implementation of the Begin Exploring Fertility Options, Risks and Expectations (BEFORE) Decision Aid
The Begin Exploring Fertility Options, Risks and Expectations (BEFORE) decision aid was created to support fertility discussions and decision-making for young breast cancer patients in Canada.
- Conditions
- Evaluation Studies, Implementation Research, Decision Aid, Young Adult Cancer
- Trial name
- BEFORE (NCT03629509)
- Testing
- Educational Webinar and Resources
- Where
- Canada
- Volunteers
- 116 people
- Sponsor
- Unity Health Toronto
Cancer, Fertility Issues
Intervening on Women's Health for Rural Young Cancer Survivors
The purpose of this pilot study is to evaluate the feasibility of a multi-component intervention to improve young female cancer survivors' engagement in goal-concordant reproductive health care.
- Conditions
- Cancer, Fertility Issues, Contraception
- Trial name
- NCT06664034
- Testing
- Multi-component reproductive health care intervention
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Endometriosis, Unexplained Infertility
Elagolix for Fertility Enhancement Clinical Trial
Studies suggest that undiagnosed endometriosis results in poor reproductive outcomes in the setting of In Vitro Fertilization and Embryo Transfer (IVF-ET).
- Trial name
- EFFECT (NCT04039204)
- Testing
- Elagolix, Ortho Cyclen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Fertility, Male, Sub-Fertility, Male
Study of the Consumer Use of a New Home Test to Measure Sperm Concentration
The objective of the study is to evaluate the agreement in measurement of sperm concentration in human semen between lay users with TRAK and a recognized reference method.
- Trial name
- NCT02475395
- Testing
- TRAK device
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Sandstone Diagnostics
Transgender Adolescents & Young Adults
Fertility Decision-Making in Youth and Young Adults
The aim of this study is to test if using a web-based medical decision-making tool on the topics of fertility and fertility-preservation increases knowledge among transgender youth and young adults.
- Trial name
- NCT05175170
- Testing
- Decision-aid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Amenorrhea, Premature Ovarian Failure
GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
Primary Objectives: To determine the effectiveness of the 3-month depot leuprolide in inducing and maintaining secondary amenorrhea in patients undergo hematopoietic stem cell transplantation.
- Conditions
- Amenorrhea, Premature Ovarian Failure, Ovarian Function Insufficiency
- Trial name
- NCT00429494
- Testing
- Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Infertility
Involuntary Childlessness and Stress Management
Many couples experience involuntary childlessness and seek treatment at fertility clinics. Going through treatment procedures can be very challenging, time consuming and emotionally demanding.
- Trial name
- NCT01187095
- Testing
- Expressive writing, Active ctrl
- Where
- Denmark
- Volunteers
- 298 people
- Sponsor
- University of Aarhus
Uterine Fibroids, Fertility Disorders
Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery
The purpose of this study was to evaluate clinically the efficacy of the PREVADH® Film in the prevention of adhesions in gynaecologic surgery, and to assess post-operative complications related to adhesions and pregnancy rate…
- Trial name
- NCT01388907
- Testing
- Ringer lactate solution, Prevadh film
- Where
- 11 sites in France
- Volunteers
- 61 people
- Sponsor
- Medtronic - MITG
Reproductive Issues, Reproductive Disorder
An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data
Aim to investigate the efficacy of follitropin alpha biosimilar therapy (Primapur®) in nonselected real-world population.
- Conditions
- Reproductive Issues, Reproductive Disorder, Fertility Disorders, Fertility Issues
- Trial name
- NCT04854707
- Testing
- Follitropin Alfa, Follicle Stimulating Hormone/Luteinizing Hormone
- Where
- 35 sites in Russia
- Volunteers
- 5,484 people
- Sponsor
- IVFarma LLC
Breast Cancer
Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer
Primary Objective: To determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing neoadjuvant and/or adjuvant chemotherapy for primary invasive breast cancer by…
- Trial name
- NCT00429403
- Testing
- Goserelin
- Where
- 2 sites in United States, Japan
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center