Clinical trials: Fertility
Polycystic Ovary Syndrome
Improving Reproductive Function in Women With Polycystic Ovary Syndrome by High Intensity Interval Training
The aim is to investigate whether 16 weeks of high intensity interval training, followed by 36 weeks of home-based exercise, will improve menstrual frequency in women with Polycystic Ovary Syndrome (PCOS) compared with a…
- Trial name
- IMPROV-IT (NCT02419482)
- Testing
- 4x4 minutes high intensity interval training, 10x1 minute high intensity interval training
- Where
- 2 sites in Australia, Norway
- Volunteers
- 64 people
- Sponsor
- Norwegian University of Science and Technology
Sperm, Fertility
Ejaculation Frequency and Semen Parameters
The goal of this observational study is to determine whether the frequency of ejaculation in men had an effect on semen parameters..
- Trial name
- EFASP (NCT06172504)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- The First Hospital of Jilin University
Infertility, Male
Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples
The purpose of this research study is to evaluate if special types of cells called round spermatids can be gathered from men with non-obstructive azoospermia and used (in absence of elongated spermatids and spermatozoa) to…
- Trial name
- ROSI (NCT04298255)
- Testing
- Round Spermatid Injection (ROSI), Half ROSI-half Sperm Donor Fertilization
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Endometriosis, Quality of Life
The Impact of NOSE-colectomy on Fertility and Quality of Life Among Patients With Colorectal Endometriosis
Deep infiltrating endometriosis (DIE) represents the most severe form of endometriosis and is present in 20-35% of all women suffering from the disease. Intestinal nodules are observed in 3% to 37% of endometriosis patients.
- Trial name
- NOSERES (NCT04109378)
- Testing
- Surgical procedures( conventional laparoscopic and NOSE technique) for the treatment of colorectal DIE
- Where
- Hungary
- Volunteers
- 150 people
- Sponsor
- Semmelweis University
HIV-1, Fertility
Intrauterine Insemination In HIV-Discordant Couples
This study aims to assess the feasibility of a novel standard of care technique for intrauterine insemination (IUI) in HIV-discordant couples in the United States.
- Conditions
- HIV-1, Fertility, Infertility
- Trial name
- ARTEMIS (NCT01173276)
- Testing
- Sperm Washing with Intrauterine Insemination (IUI)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Fertility Disorders
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
In-vitro fertilisation (IVF) treatment involves women undergoing hormone stimulation (drug dosing) to produce more oocytes (eggs) to increase their chances of fertilisation.
- Trial name
- NCT05634850
- Testing
- Kinder
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Planet Innovation
Fertility Preservation
Correlation of Oxidative Stress and Oocyte Quality in Fertility Preservation
Whether it is for oncology or personal reasons, fertility preservation allows participants to preserve their oocytes (eggs) at their current age and condition for a better chance of having a baby in the future.
- Trial name
- Ooxyd (NCT05372549)
- Testing
- Oxidative stress, cf-DNA, MAGENTA AI
- Where
- 3 sites in Canada
- Volunteers
- 179 people
- Sponsor
- Clinique Ovo
Infertility
Diafert® for Embryo Selection and Fertility Improvement
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593461)
- Testing
- Daifert, Control Group
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Forest Laboratories
Ectopic Pregnancy
Cornual Pregnancy: Results of a Single-center Retrospective Experience and Systematic Review on Reproductive Outcomes
To present our experience in the diagnosis and management of cornual pregnancy. A systematic review was also conducted to investigate reproductive outcomes after treatment.
- Trial name
- NCT06165770
- Testing
- laparoscopy
- Volunteers
- 17 people
- Sponsor
- University of Palermo
Male Infertility, Heart Valve Disease
Warfarin Effects on Male Fertility After Cardiac Surgery
Young male patients undergoing cardiac surgery may require oral anticoagulation with warfarin either lifelong, such as after mechanical valve replacement, or for a limited postoperative period, for example following valve repair…
- Trial name
- NCT07330869
- Testing
- Semen analysis, sperm DNA fragmentation and hormonal evaluation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Città di Lecce Hospital, GVM Care & Research
Fertility Disorders
Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI
Intrauterine Granulocyte colony stimulating factor (GCSF) was compared with intrauterine Human Chorionic Gonadotropin (HCG) in increasing clinical pregnancy rate as a primary outcome and ultrasound imaging of gestational sac as a…
- Trial name
- NCT04606082
- Testing
- Granulocyte Colony Stimulated Factor, Human Chorionic Gonadotropins
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Fertility, In Vitro Fertilization
A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
In vitro fertilization (IVF) treatment is now commonly used to treat infertile couples. During IVF treatment, oocytes and sperm are routinely incubated overnight and this may lead to suboptimal culture conditions because of…
- Trial name
- NCT02534857
- Testing
- a shorter exposure of oocyte to spermatozoa
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Fertility, SPERM
Male Fertility and Sperm Cryopreservation
PURPOSE: Primary objective: To assess the feasibility and outcomes of male fertility preservation by sperm freezing prior to starting treatment requiring alkylating agents and/or total body irradiation.
- Conditions
- Fertility, SPERM, Cancer
- Trial name
- NCT02431000
- Testing
- Sperm and blood collected for analysis
- Where
- United States
- Sponsor
- University of Tennessee
Endometrial Carcinoma, Obese
Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma
To investigate the efficacy of weight management plus megestrol acetate in obese patients with early endometrioid carcinoma（EEC）asking for fertility-sparing treatment
- Conditions
- Endometrial Carcinoma, Obese, Overweight, Fertility Issues
- Trial name
- NCT05316467
- Testing
- Intensive Lifestyle Intervention (ILI), Megestrol Acetate 160 MG Oral Tablet
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Xiaojun Chen
Atypical, Myoma
Transcervical Myoma Biopsy Video
To describe the fertility-sparing management of an atypical uterine myoma. Step-by-step video explanation of transcervical biopsy using transabdominal ultrasound guidance, highlighting tips and tricks.
- Trial name
- TMBV (NCT04983719)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
Oncological Disease, Fertility Preservation
Ovulation Induction With GnRH Analogue or Dual Trigger?
Most medically assisted procreation (ART) techniques, including oocyte cryopreservation for fertility preservation, involve controlled ovarian stimulation.
- Trial name
- NCT07546136
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Fertility Disorders, Infertility (IVF Patients)
The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women
This randomized controlled trial aimed to determine whether a mindfulness-based lifestyle support program would improve quality of life, lifestyle, mindfulness, attention and meditation level and treatment outcomes in women…
- Trial name
- NCT06799507
- Testing
- Interventions Based on Mindfulness, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Fertility Issues
Continuous Double Ovarian Stimulation.
To evaluate the efficacy of the weekly use of corifollitropin alfa in double ovarian stimulation process and to compare it to the conventional protocol with daily medication administration.
- Trial name
- NCT05815719
- Testing
- Corifollitropin Alfa, Follitropin Alfa, Follitropin Alfa Biosimilar
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Hysteroscopic Metroplasty and Myomectomy
Hysteroscopic Surgery; Retrospective Cross-sectional Study of Reproductive Outcome
study of the effect of hysteroscopic sptoplast and hysteroscopic myomectomy on reproductive performance of patients with infertility and /or miscarriages
- Trial name
- NCT05560295
- Testing
- Naser Al-Husban
- Volunteers
- 165 people
- Sponsor
- University of Jordan