Clinical trials: Fatal Outcome
Infection Due to Resistant Bacteria, Multi-antibiotic Resistance
Resistant Bacteria in Children in France
This study is observational, multicenter and prospective study for surveillance of the use of new antibiotics in pediatrics for treated pediatrics infections due to multi-resistant bacteria
- Conditions
- Infection Due to Resistant Bacteria, Multi-antibiotic Resistance, Antibiotic Prescription, Risk Factors
- Trial name
- BREF (NCT06036628)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Surgery, Anesthesia
Russian Registry of Surgical OutcomeS
Identification of risk factors that cause a high probability of an unfavorable outcome in the postoperative period is an urgent problem.
- Conditions
- Surgery, Anesthesia, Outcome, Fatal, Complication
- Trial name
- RuSOS (NCT06146270)
- Where
- 16 sites in Russia
- Volunteers
- 162,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Apatinib, Outcome, Fatal
Apatinib for Resectable Colorectal Cancer
Objective: To compare the outcome of patients with colorectal cancer who treated with adjuvant therapy or Apatinib with adjuvant therapy postoperatively. Language: English.
- Conditions
- Apatinib, Outcome, Fatal, Colorectal Cancer, Surgery
- Trial name
- NCT03228043
- Testing
- Apatinib, CAPEOX
- Where
- China
- Sponsor
- Nanchong Central Hospital
Frailty, Surgery--Complications
Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy
In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.
- Conditions
- Frailty, Surgery--Complications, Outcome, Fatal, Frail Elderly Syndrome
- Trial name
- (ProPEL) (NCT04293653)
- Testing
- Protocol for patients above 75 undergoing emergency laparotomy or laparoscopy
- Where
- Norway
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Sepsis Due to Streptococcus, Group A, Risk Factors
Invasive Group A Streptococcal Infection
This study is observational, retrospective and prospective study in pediatric patients hospitalized with invasive streptococcal A infection
- Conditions
- Sepsis Due to Streptococcus, Group A, Risk Factors, Severe Infection, Medical Care
- Trial name
- ISAI (NCT05788861)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
COVID-19, Outcome, Fatal
Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application
In a retrospective observational study, critically ill COVID-19 patients admitted to the ICU with the CoV-2 delta-variant between august 2021 and february 2022 were evaluated (ethics application nr.
- Conditions
- COVID-19, Outcome, Fatal, Tocilizumab, Interleukin 6
- Trial name
- CasiTocCOVID (NCT06233357)
- Testing
- treated without (N), with casirivimab / imdevimab (C) or tocilizumab (T), solely, or in combination of both (C + T)
- Where
- Germany
- Volunteers
- 95 people
- Sponsor
- University of Ulm
Septic Shock, Multiple Organ Failure
Severe Sepsis/Septic Shock on Admission to the General Surgical ICU
Severe sepsis/septic shock are serious complications of infection with high morbidity and mortality. Recent information showed that early and aggressive resuscitation may help improving survival and outcome especially the…
- Conditions
- Septic Shock, Multiple Organ Failure, Fatal Outcome
- Trial name
- NCT01363635
- Where
- Thailand
- Volunteers
- 800 people
- Sponsor
- Mahidol University
Covid19, Outcome, Fatal
International Study of Inflammation in COVID-19
This is a prospective multi-center observational study which purpose is to evaluate the ability of blood-based inflammatory markers to risk-stratify patients hospitalized for Covid-19.
- Conditions
- Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury
- Trial name
- ISIC (NCT04818866)
- Testing
- SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase
- Where
- United States
- Volunteers
- 4,463 people
- Sponsor
- University of Michigan
Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral
Early Warning of Delayed Cerebral Ischemia
The goal of this observational study is to learn about the possibility to predict clinical course of subarachnoid hemorrhage (SAH) patients by performing the retrospective analysis of clinical data available in early…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral, Ischemia, Outcome, Fatal
- Trial name
- EWoDCI (NCT06006975)
- Testing
- Computed Tomography (CT) and Computed Tomography Angiography (CTA), Multimodal physiological monitoring
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Vilnius University
Extracorporeal Membrane Oxygenation Complication, Outcome, Fatal
Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.
In the context of the coronavirus (COVID-19) pandemic, healthcare systems worldwide faced an unprecedented shortage of severe ARDS.
- Trial name
- NCT05338593
- Testing
- Outcome
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Traumatic Brain Injury, Fluid Overload
Neutral Versus Liberal fLuId In Traumatic Brain Injury: a Randomised Controlled Trial
Feasibility and safety of targeting neutral vs liberal fluid balance in traumatic brain injured patients: a phase II randomized controlled trial
- Conditions
- Traumatic Brain Injury, Fluid Overload, Outcome, Fatal
- Trial name
- LIMIT (NCT05983549)
- Testing
- fluid balance
- Volunteers
- 80 people
- Sponsor
- Universita degli Studi di Genova
Resuscitation, Outcome, Fatal
Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland
Sudden cardiac arrests is one of the most frequent causes of death. In Switzerland every year 8000-10.000 people suffer from a cardiac arrest.
- Conditions
- Resuscitation, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT03759210
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Outcome, Fatal, Spondylodiscitis
Spine Registry University Hospital of Cologne- Department of Orthopedics
Between January 2008 and December 2020 all patients with spine diseases were registered prospectively in the former European Spine Tango registry and later german DWG registry at the department of orthopedics and trauma at the…
- Conditions
- Outcome, Fatal, Spondylodiscitis, Vertebral Osteomyelitis
- Trial name
- NCT05486494
- Testing
- Treatment (non- surgical/surgical)
- Volunteers
- 355 people
- Sponsor
- University of Cologne
Outcome, Fatal
The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit
A retrospective observational study on the HIV testing trend and outcomes in a trauma population admitted to a critical care unit for care.
- Trial name
- NCT05484947
- Testing
- Elisa HIV testing
- Where
- South Africa
- Volunteers
- 868 people
- Sponsor
- University of Witwatersrand, South Africa
Adnexal Mass, Perioperative Complication
Preoperative Care In Ovarian Cancer Patients
A randomised controlled trial study consisting of two-group pretest-post-test.
- Conditions
- Adnexal Mass, Perioperative Complication, Outcome, Fatal
- Trial name
- NCT04260334
- Testing
- Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Dokuz Eylul University
Acute Coronary Syndrome, Procedural Complication
Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study
The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications.
- Conditions
- Acute Coronary Syndrome, Procedural Complication, Outcome, Fatal
- Trial name
- DONATION-OB (NCT05230719)
- Testing
- Radial Artery Approach
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shenzhen People's Hospital
Outcome, Fatal
Oxygen Pulse and Its Curve Patterns in Male Patients With Heart Failure and Chronic Obstructive Pulmonary Disease With and in Healthy Men
Background: In non-invasive cardiopulmonary exercise testing (CPET), oxygen pulse (O2P) is defined as oxygen uptake divided by heart rate and is equal to the product of stroke volume and oxygen extraction by cells.
- Trial name
- NCT05189301
- Testing
- first pass study, cardiopulmonary exercise testing
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chung Shan Medical University
Surgery, Surgery--Complications
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated.
- Conditions
- Surgery, Surgery--Complications, Neurological Morbidity, Neurological Diseases or Conditions
- Trial name
- NCT05097066
- Testing
- Neurosurgical procedure
- Volunteers
- 371,418 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Transposition of Great Vessels, Outcome, Fatal
Outcomes of Transposition of the Great Arteries After Arterial Switch Operation
Transposition of the great arteries (TGA) is a complex cyanotic congenital heart disease and patients suffer from a high mortality rate within one year of age without appropriate management.
- Trial name
- NCT05089773
- Testing
- The arterial switch operation
- Where
- 2 sites in China
- Volunteers
- 1,281 people
- Sponsor
- Children's Hospital of Fudan University
COVID-19, Critical Illness
Analysis of Mortality of Critically Ill Patients With COVID-19
The recent pandemic of the COVID-19 disease has caused a national health emergency due to its severity and the clinical and social consequences of the disease. Crude mortality in Spain is 9.2%.
- Conditions
- COVID-19, Critical Illness, Effectiveness, Outcome, Fatal
- Trial name
- NCT04379258
- Where
- Spain
- Volunteers
- 868 people
- Sponsor
- Hospital Universitario Getafe