Clinical trials: Family Relations
Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency, Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy)
Congenital Muscle Disease Study of Patient and Family Reported Medical Information
The Congenital Muscle Disease Patient and Proxy Reported Outcome Study (CMDPROS) is a longitudinal 10 year study to identify and trend care parameters, adverse events in the congenital muscle diseases using the Congenital Muscle…
- Conditions
- Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency, Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy), Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Fatty Liver and Infantile-onset Cataract Caused by TRAPPC11 Mutations), Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Hypoglycosylation of Dystroglycan)
- Trial name
- CMDPROS (NCT01403402)
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- Cure CMD
Family Relations
Use ICT to Promote Family Well-being in Hong Kong
In the past few decades, Information and Communications Technology (ICT) have rapidly developed as effective, and probably the most cost-effective tools to connect most aspects of family lives.
- Trial name
- NCT04065867
- Testing
- ICT activities
- Where
- Hong Kong
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Transthyretin Cardiomyopathy (TTR-CM), Transthyretin (TTR) Amyloid Cardiomyopathy
PL_GNT01_ISR_Grant 53234273
We carry out a prospective non-interventional, longitudinal, observational multicentre registry designed to improve our understanding of the epidemiology of TTR amyloidosis in our country.
- Conditions
- Transthyretin Cardiomyopathy (TTR-CM), Transthyretin (TTR) Amyloid Cardiomyopathy, Transthyretin Amyloidosis
- Trial name
- NCT06714019
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Amyloidosis, Hereditary, Transthyretin Amyloidosis
HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
The purpose of this study is to evaluate the efficacy and safety of vutrisiran (ALN-TTRSC02) in participants with hereditary transthyretin amyloidosis (hATTR amyloidosis).
- Trial name
- NCT03759379
- Testing
- Patisiran, Vutrisiran
- Where
- 64 sites in United States, Argentina and 20 more
- Volunteers
- 164 people
- Sponsor
- Alnylam Pharmaceuticals
Cancer, Malignancies Multiple
CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)
This study will collect data on Canadian cancer patients that have uncommon/rare changes in their tumours, such as alterations/rearrangements in the genetic material inside cells - known as deoxyribonucleic acid, or DNA, which…
- Conditions
- Cancer, Malignancies Multiple, Malignant Solid Tumor, Cancer, Therapy-Related
- Trial name
- CARMA-BROS (NCT04151342)
- Testing
- Cancer treatment with tyrosine kinase inhibitors (TKIs) or other molecularly targeted therapeutic agents., Patient-reported outcomes (PROs)
- Where
- 27 sites in Canada
- Volunteers
- 5,500 people
- Sponsor
- University Health Network, Toronto
Stroke
Fangshan / Family-based Ischemic Stroke Study In China
The exact etiology of ischemic stroke remains unclear, because multiple genetic predispositions and environmental risk factors may be involved, and their interactions dictate the complexity.
- Trial name
- FISSIC (NCT00534742)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University
Parent-Child Relations, Child Development
FamilieTrivsel i Almen Praksis: a Mentalisation Programme for Families With Young Children
This cluster randomised trial aims to establish the effectiveness of an online intervention designed to improve the ability of parents to 'mentalise' - in other words to understand their own mental states and that of others…
- Conditions
- Parent-Child Relations, Child Development, Parenting
- Trial name
- NCT04129359
- Testing
- FamilieTrivsel, enhanced care as usual
- Where
- Denmark
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Transthyretin (TTR) Amyloid Cardiomyopathy
Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
The objective of this study is to determine the association of clinically prescribed, on-label, TTR stabilizing therapy (e.g. tafamidis or acoramidis) with levels of circulating transthyretin amyloid aggregates (TAAs, a surrogate…
- Trial name
- NCT07196839
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Substance Use, Child Abuse
A Regional Partnership to Improve Outcomes Through Fatherhood Engagement
Montefiore will engage fathers in families at risk of substance misuse in the Bronx and neighboring communities. Families will be referred from Bronx and neighboring community-based child welfare systems, substance use disorder…
- Conditions
- Substance Use, Child Abuse, Child Neglect, Fathers
- Trial name
- NCT05562557
- Testing
- Motivational Enhancement, HERO Dads Fatherhood Program, Contingency Management
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Mental Health Issue, Family Dynamics
Single-Session Psychotherapy for Young Kids Through Patient Engagement Techniques
The goal of this clinical trial is to compare outcomes between participants in the single-session psychotherapy for young kids (SPYKids) conditions and participants in the services as usual (SAU) condition.
- Conditions
- Mental Health Issue, Family Dynamics, Stress, Psychological, Stress, Emotional
- Trial name
- SPYKids (NCT05857865)
- Testing
- SPYKids, Services as Usual (SAU)
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Familial Hemiplegic Migraine
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to Calcitonin Gene Related Peptide (CGRP)infusion.
- Trial name
- NCT00358839
- Testing
- CGRP
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Child Development, Child Behavior
The Infant- Toddler Climate of Healthy Interactions for Learning and Development (I-T CHILD)
The purpose of the study is to train New York-based early childhood mental health consultants (ECMHCs) who will apply the Infant-Toddler Climate of Healthy Interactions for Learning and Development (I-T CHILD) tool as part of…
- Conditions
- Child Development, Child Behavior, Social Skills, Infant Development
- Trial name
- I-T CHILD (NCT05132374)
- Testing
- I-T CHILD
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Parenting, Parent-Child Relations
Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth
The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system.
- Conditions
- Parenting, Parent-Child Relations, Child Behavior, Child Maltreatment
- Trial name
- NCT06109766
- Testing
- Promoting First Relationships
- Where
- United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- University of Washington
Bipolar Disorder
Family Focused Therapy for Teens at Risk for Bipolar Disorder
The present study aims to examine the effects of a 4 month, family focused therapy (FFT) intervention on the 1 year course of mood symptoms in offspring of parents with bipolar disorder (BD).
- Trial name
- NCT02355366
- Testing
- Family-Focused Therapy, Brief Educational Treatment
- Where
- Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pancreatic Cancer
Pancreatic Intraepithelial Neoplasia (PanIN) and the Association With Recurrence of Pancreatic Adenocarcinoma
The research purpose of this project is to create a registry, and blood and tissue bank for individuals at high-risk for pancreatic cancer.
- Trial name
- NCT01219829
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Caregiver Stress, Caregiver Health Related QOL
Applying CSNAT in HBPC as an Approach to Elder Mistreatment Risk Reduction
This study will evaluate the feasibility, acceptability, and preliminary effects of the Carer Support Needs Assessment Tool (CSNAT) intervention for family caregivers of older adults receiving home-based primary care.
- Conditions
- Caregiver Stress, Caregiver Health Related QOL, Caregiver Mental Health, Caregiver Health Status
- Trial name
- NCT07749482
- Testing
- CSNAT-I
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Substance Abuse, Substance Use
Enhancing Permanency in Children and Families
The Enhancing Permanency in Children and Families (EPIC) program is a collaborative effort between the Ohio State University College of Social Work, two county offices of the Ohio Department of Job and Family Services, two…
- Conditions
- Substance Abuse, Substance Use, Child Abuse, Neglect, Child
- Trial name
- EPIC (NCT04700696)
- Testing
- Peer Recovery Support, Family Treatment Drug Court with Medications for Opioid Use Disorders (MOUD), Relational Skill Building based on the Nurturing Parenting Program (NPP)
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Ohio State University
Intensive Care Neurological Disorder
Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation
The current study has the following objectives: 1. To determine predictors of time 2 and 3 (3 and 6 months post-ICU admission) depression, PTSD, satisfaction with life and quality of life in both patients and caregivers, after…
- Trial name
- NCT02435641
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, SARS-CoV-2
Anxiety, Depression and Eating Attitudes of Diabetes Mellitus Patients During COVID-19 Lockdown in Greece
The aim of this observational, cross-sectional study is to evaluate the impact of the second national COVID-19 lockdown in Greece, regarding the aspects of depression, anxiety and eating habits, in relation to the adjusted work…
- Trial name
- NCT04700254
- Testing
- DASS questionnaire, EAT-26 questionnaire
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chania General Hospital "St. George"
Family Conflict, Internet-Based Intervention
Love Together, Parent Together: A Feasibility Study
The COVID-19 pandemic has introduced additional stressors and challenges to couples' relationships, with potential ripple effects across all family subsystems and child adjustment.
- Trial name
- L2P2 (NCT05143437)
- Testing
- Love Together Parent Together
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- York University