Clinical trials: Fainting
Syncope
The Diagnostic Performance of Tilt Test in Athletes
In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt.
- Trial name
- NCT02316860
- Testing
- Passive tilt test
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Syncope
Effect of Psychotherapy on Quality of Life and Recurrence of Events in Patients With Recurrent Vasovagal Syncope: A Randomized Pilot Study
Recurrent vasovagal syncope although presenting a benign prognosis in terms of survival, is associated with significant impairment of quality of life.
- Trial name
- NCT04252729
- Testing
- Psychotherapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Mauricio Ibrahim Scanavacca
Vitamin D
Correlation Between Vitamin D and Symptoms Severity of Autonomic Nervous Mediated Syncope Child and it 's RAAS
children ; autonomic nervous mediated syncope； vitamin D ; symptom score ; renin-angiotensin-aldosterone-system
- Trial name
- NCT04844957
- Testing
- Vitamin D, Full automatic chemiluminescence measuring instrument
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kongyujie
Cardiac Arrythmias, Syncope
Confirm Rx™ Versus Reveal LINQ™ - Which is More Reliable in Data Transmission? A Randomized Clinical Study
This study will compare the reliability and timeliness in data transmission of the Abbott Confirm Rx™ loop recorder with the Medtronic Reveal LINQ™ loop recorder.
- Conditions
- Cardiac Arrythmias, Syncope, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT03720639
- Testing
- Abbott, Inc Confirm Rx™ versus Medtronic, Inc Reveal LINQTM
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Sparrow Clinical Research Institute
Tachycardia, Ventricular, Implantable Cardioverter Defibrillator (ICD)
PREPARE - Primary Prevention Parameters Evaluation
The purpose of this study is to test specific device programming in patients without a previous history of a life-threatening, abnormally fast heartbeat who are implanted with a Medtronic ICD (Implantable Cardioconverter…
- Conditions
- Tachycardia, Ventricular, Implantable Cardioverter Defibrillator (ICD), Fibrillation, Ventricular, Syncope
- Trial name
- NCT00279279
- Testing
- Implanted Device
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 700 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Syncope, Pulmonary Embolism
Prevalence of Pulmonary Embolism in Patients With Syncope
All patients consecutively referred with the first episode of transient and short-lasting loss of consciousness will have a diagnostic workup for the assessment of the most common causes of syncope, and will be evaluated for the…
- Trial name
- PESY (NCT01797289)
- Testing
- Lung CT or V/Q scanning in patients with a high pre-test clinical probability of PE and/or a positive D-dimer
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- University of Padova
Pulmonary Arterial Hypertension
Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients
This was a non-confirmatory, randomized, placebo controlled, subject and investigator blinded study of QCC374 in PAH subjects. The study was planned to have 2 Parts: Part 1, an initial safety cohort with a 0.03 mg bid starting…
- Trial name
- NCT02927366
- Testing
- QCC374
- Where
- 5 sites in United States, Germany and 2 more
- Volunteers
- 8 people
- Sponsor
- Novartis Pharmaceuticals
Vasovagal Syncope
Effect of Closed Loop Pacemaker Treatment on Recurrent Vasovagal Syncope
The main purpose is to prevent syncope in patients with recurrent syncopal episodes caused by malignant vasovagal faints and bradycardia.
- Trial name
- NCT00292825
- Testing
- Pacemaker treatment, pacemaker programmed as active = CLS, Pacemaker, programmed as passive = VVI 30 beats per minute (bpm)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital Skejby
Syncope, Vasovagal
Midodrine and Fludrocortisone for Vasovagal Syncope
Syncope is a common condition which can disturb daily functions of the patients and impair their quality of lives. It contributes to 0.8 to 2.4% of the visits of emergency rooms.
- Trial name
- COMFORTS (NCT04595942)
- Testing
- Midodrine Hydrochloride Tablets, Fludrocortisone Acetate Tablets, Lifestyle modification
- Where
- Iran
- Volunteers
- 1,375 people
- Sponsor
- Tehran Heart Center
PHYSIOLOGICAL PHENOMENA
Importance of Liver Innervation for the Osmopressor Response in Humans
In patients with autonomic dysfunction water drinking elicits a pressor response mediated by sympathetic activation. If any, in healthy subjects there is only a slight increase in blood pressure.
- Trial name
- HEP-Reflex (NCT01237431)
- Testing
- 500ml water intake
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Hannover Medical School
ATRIAL FIBRILLATION, Syncope
BioMonitor Master Study
The BioMonitor is an implantable cardiac monitor used to automatically detect and record episodes of arrhythmia in patients with bradycardia, tachycardia, asystole and atrial fibrillation.
- Trial name
- BioMonitor (NCT01725568)
- Testing
- BioMonitor
- Where
- Germany
- Volunteers
- 152 people
- Sponsor
- Biotronik SE & Co. KG
Orthostatic Hypotension, Syncope
The Effect of Water Carbonation on Orthostatic Tolerance
The primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers.
- Conditions
- Orthostatic Hypotension, Syncope, Vasovagal Syncope
- Trial name
- NCT05621460
- Testing
- 500mL carbonated water, 500mL still water, 50mL still water
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Arrhythmia, Children
Optimizing Diagnostics Of Arrhythmia Events In Children Using Intelligent Telemetric Solutions
The purpose of this study is to assess efficacy of prolonged Full Disclosure electrocardiogram (ECG) monitoring and signal analysis using advanced telemetric technology to diagnose arrhythmia in comparison with standard…
- Trial name
- TELEMARC2 (NCT01265771)
- Testing
- Prolonged telemetric Full Disclosure ECG recording., Repeated 24 hours ECG Holter monitoring
- Where
- 3 sites in Poland
- Volunteers
- 400 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Syncope, Vasovagal
Wearable Monitor in Patients With Syncope
The main purpose of this study is to assess the reliability of a new patient's self-administered wearable watch-type BP monitor in detecting episodes of hypotensive (pre)syncope.
- Trial name
- Watch-VD (NCT05782647)
- Testing
- HeartGuide cuffless BP monitor
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Istituto Auxologico Italiano
Tachyarrhythmia, Atrial Fibrillation
BIO.MASTER.BioMonitor 2 Study
The objective of the study is to confirm safety and efficacy of the BioMonitor 2. The data is collected to support the regulatory approval of this product in countries outside the CE region.
- Conditions
- Tachyarrhythmia, Atrial Fibrillation, Syncope
- Trial name
- NCT02565238
- Testing
- BioMonitor 2
- Volunteers
- 92 people
- Sponsor
- Biotronik SE & Co. KG
Syncope
Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department
This is a observational prospective study. For patients presenting to the Emergency Department with loss of consciousness, emergency physicians will be asked to screen the real syncope without an evident and immediate cause for…
- Trial name
- NCT02781207
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- University of Turin, Italy
Neurally Mediated Syncope
Italian Cardioneuroablation Study for Neurocardiogenic Syncope Patients
Multicenter Italian interventional "proof of efficacy" clinical trial that aims to evaluate the incidence of asystolic pauses and heart rate in patients with CNS who performed severe CNA identified through asystolic pauses…
- Trial name
- ItalianCNA (NCT05751330)
- Testing
- Transcatheter ablation of cardiac ganglionated plexi
- Where
- 2 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Policlinico Casilino ASL RMB
Bradycardia, Sinus Node Dysfunction
Physiologic Pacing Registry
The Physiologic Pacing Registry is a prospective, observational, multi-center registry performed to gain a broader understanding of 1) physiologic pacing implant and follow-up workflows, including pacing and sensing measurements…
- Conditions
- Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope
- Trial name
- NCT03719040
- Testing
- Physiologic pacing device implant
- Where
- 50 sites in United States, Australia and 14 more
- Volunteers
- 870 people
- Sponsor
- Abbott Medical Devices
Syncope
Haemodynamic Feasibility Study of Sensors Within a Tilting Table Examination
This study´s aim is to explore physiological associations concerning pulse wave velocity, heart rate and blood pressure in order to make taking the blood pressure more comfortable.
- Trial name
- NCT01831297
- Testing
- measurement of blood pressure
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- RWTH Aachen University