Clinical trials: Faecal Incontinence
Fecal Incontinence, Bowel Incontinence
Fecal Incontinence Treatment (FIT) Study
Patients with severe fecal incontinence (FI), defined as two or more episodes of staining, solid or liquid FI per week, and who meet the inclusion criteria for Injection of Solesta (INJ; an inert bulking agent), or Biofeedback…
- Trial name
- NCT03811821
- Testing
- Biofeedback, Injection
- Where
- 6 sites in United States
- Volunteers
- 275 people
- Sponsor
- Mayo Clinic
Fecal Incontinence
Obstetric Fecal Incontinence Treatment Registry
INTRODUCTION Anal Incontinence (AI) is a loose of voluntary control for bowel movements, with recurrent leaking of flatus, liquid or solid stools. AI is a frecuent pathology. Prevalence is similar among men and women.
- Trial name
- NCT04727463
- Testing
- Sphincteroplasty
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital San Carlos, Madrid
Rectal Cancer, Low Anterior Resection Syndrome
Autologous Fecal Microbiota Transplantation for Anal Function Recovery After Ileostomy Reversal in Rectal Cancer
This prospective, single-center, single-arm, open-label clinical study aims to evaluate whether autologous fecal microbiota transplantation can improve bowel and anal function after ileostomy reversal in patients with rectal…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Fecal Incontinence, Diversion Colitis
- Trial name
- NCT07711509
- Testing
- Autologous Fecal Microbiota Transplantation
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Peking University People's Hospital
Faecal Incontinence, Faecal Incontinence With Faecal Urgency
Acs-Tens Treatment for Faecal Incontinence: a RCT With Sham-controls
This study assess the effectiveness on AcuTENS on the treatment of faecal incontinence
- Conditions
- Faecal Incontinence, Faecal Incontinence With Faecal Urgency, Neuromodulation, Transcutaneous Electric Nerve Stimulation
- Trial name
- NCT04749316
- Testing
- AcuTENS
- Where
- Hong Kong
- Volunteers
- 53 people
- Sponsor
- Chinese University of Hong Kong
Fecal Incontinence, Pelvic Floor Disorders
Validity and Reliability of the Turkish St. Marks Incontinence Score
For the Turkish validity and reliability study of St.Mark's (Vaizey) Incontinence Score, which consists of 7 questions, it will be applied to 65 people diagnosed with anal incontinence after it is translated by…
- Trial name
- NCT05755763
- Testing
- Anal incontinence patients with St. Mark's Incontinence Score
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Atlas University
Fecal Incontinence
Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
This is first-in-human prospective Phase I study of the immediate and long-term safety of an implanted internal anal sphincter (IAS) bioengineered from autologous cells to treat subjects with severe passive FI who have failed…
- Trial name
- NCT05616208
- Testing
- Bioengineered Internal Anal Sphincter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cellf Bio LLC
Fecal Incontinence
Effect of Anorectal Biofeedback on Encopresis in School Aged Girls After Sexual Assault
Females who have been sexually abused anally, have a disturbed anorectal motility. They have an increased resting pressure at the lower part of the anal canal.
- Trial name
- NCT04652024
- Testing
- Anorectal manometry
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Badr University
Spina Bifida, Neurogenic Bowel
Bowel Continence Across the Lifespan in People With Spina Bifida
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida.
- Conditions
- Spina Bifida, Neurogenic Bowel, Bowel Incontinence
- Trial name
- BCALS (NCT07390318)
- Testing
- Retrograde Enema, Antegrade Enema
- Where
- 24 sites in United States
- Volunteers
- 943 people
- Sponsor
- David Chu
Faecal Incontinence
Computational Model of SNS (Sacral Nerve Stimulation) Induced Electrical Current Flow Using Tractography Imaging
This study aims to obtain finer details of tissues surrounding a lead in the pelvis using a combination of high-resolution anatomical MRI sequences and diffusion tensor imaging (DTI).
- Trial name
- NCT05049486
- Testing
- CT scan
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- London North West Healthcare NHS Trust
Anorectal Disorder, Fecal Incontinence
Normal Values in Ano-rectal 3D High Resolution Manometry
Ano-rectal manometry is indicative in patients with either fecal incontinence or constipation. Recently anorectal 3D- high resolution manometry has been developed.
- Conditions
- Anorectal Disorder, Fecal Incontinence, Constipation
- Trial name
- NOMAD (NCT01710579)
- Testing
- Anorectal 3D-high resolution manometry, Anorectal radial endosonography (rotative 360° probe), Dynamic anorectal endosonography (sagittal and radial)
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Constipation, Fecal Incontinence
Sierra High Definition Ano-Rectal Manometry
Hypotheses: High definition manometry (HDM) is safe and feasible in humans; HDM accurately characterizes anorectal anatomy and function in healthy humans; HDM provides comparable information regarding the structure and function…
- Trial name
- NCT01300884
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Augusta University
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Woman
Urinary and Anal Incontinence in Tunisian Women
The publications on prevalence and risk factors of urinary and anal incontinence in women were performed mainly in Europe and America.
- Trial name
- NCT03386292
- Where
- Tunisia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Pelvic Floor Disorder, Female Pelvic Floor Dysfunction
Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment
Late side-effects following gynecological cancer are predominantly symptoms from the pelvic region originating from the bowels, urinary tract, lymphatic system, genitals and musculoskeletal system.
- Conditions
- Pelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary Incontinence
- Trial name
- NCT06786091
- Testing
- Pelvic floor muscle training rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 25 people
- Sponsor
- St. Olavs Hospital
Anorectal Disorder
The Guarding Reflex Anal, Study of the Modulation Function of Rectal Distension
The term Guarding Reflex refers to a progressive, involuntary increase in the external urethral sphincter activity during bladder filling.This is a mechanism of continence, preventing from unwanted urine leakage in situation of…
- Trial name
- NCT04409054
- Testing
- Cough and Valsalva effort
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Gérard Amarenco
Fecal Incontinence
Bulking Agent Versus Electrostimulation Therapy in Anal Incontinence
Randomized trial with a estimated number of 60 patients with mild or moderate anal incontinence at the clinic Physiology of the Hospital das Clínicas of the Medical School of the University of São Paulo (HC-FMUSP).
- Trial name
- Bulking (NCT03052946)
- Testing
- Bulking agent, Endoanal electrostimulation
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Rectal Cancer, Low Anterior Resection Syndrome
Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Low Anterior Resection Syndrome.
Patients with sphincter saving procedures of rectal cancer usually experience intestinal dysfunction, including difficulty emptying the bowel and faecal incontinence, leading to a detriment in the quality of life.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Faecal Incontinence
- Trial name
- PRELARS (NCT04612569)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Faecal Incontinence, Faecal Incontinence With Faecal Urgency
UCon Treatment of the Symptoms of Faecal Incontinence (FI)
UCon is a medical device for treatment of the symptoms of overactive bladder and fecal incontinence (FI). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature e.g.…
- Trial name
- NCT05864807
- Testing
- UCon
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- InnoCon Medical
Diaper Rash
Comparison of Barrier Products in the Prevention of Incontinence-associated Dermatitis in Hospitalized Elderly
In clinical practice, there are a large number of patients hospitalized with Incontinence-Associated Dermatitis. Studies are needed to determine the effectiveness of products available for disease prevention.
- Trial name
- NCT03309059
- Testing
- water and soap, zinc oxide, Non-Irritant Barrier Film
- Where
- Brazil
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Obstetric Risk Factors
Obstetrical Risk Factors for the Development of Urinary and/or Fecal Incontinence
Evaluation of Obstetrical Risk Factors for the development of Urinary and/or Fecal Incontinence according to a questionaire The questionaire will be filled by the study investigators after the women participating in the study…
- Trial name
- NCT00729417
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maaynei Hayesha Medical Center