Clinical trials: Facial Injuries
Orbital Fractures
Use of a Low Profile Titanium Mesh in Orbital Reconstruction
In craniofacial trauma, the involvement of orbital structures is noted in up to 40% of cases (Ellis 1985). Post-traumatic orbital deformities caused by incorrect reconstruction of orbital dimensions are severe complications…
- Trial name
- NCT01432964
- Testing
- Orbital revision surgery
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ocular Injury
An Observational, Qualitative Study Assessing Eye Drop Administration
This is a prospective, observational, consecutive, qualitative, multicenter study. Based on the available published evidence that supports patient challenges with eyedrop administration, the purpose of this video-capture study is…
- Trial name
- NCT05307081
- Testing
- Artificial Tears
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ocular Therapeutix, Inc.
Orbital Trauma, Orbital Fractures
Reconstruction of the Orbit With a Bioresorbable Polycaprolactone Implant
Patients with orbital injuries are entered into the trial. Age: 20 - 70. After obtaining appropriate consent, they are entered into either a control arm where reconstruction of the orbit is done with a titanium mesh (established…
- Trial name
- NCT00233922
- Testing
- Osteosheet(r)
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Acne Scars - Atrophic, Wound Healing
Effectiveness of a rhGM-CSF-containing Gel on Promoting Recovery After 1927-nm Fractional Thulium Fiber Laser Treatment of Atrophic Acne Scars.
Atrophic acne scars (AAS) is one of the most common skin sequelae following acne vulgaris. Fractional laser has shown great therapeutic potential in recent years, while there is no standard of wound care after laser resurfacing.
- Trial name
- NCT07305675
- Testing
- rhGM-CSF-containing gel, 1927-nm TFL
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Facial Defect
The Role of Antibiotics in Full Thickness Skin Graft Survival for Facial Reconstructive Surgery
Antibiotics are sometimes prescribed to patients who have had reconstructive surgery of wounds on their face using skin grafts. But, it is not yet known whether antibiotics improve the healing of skin grafts and reduce the risk…
- Trial name
- NCT01912651
- Testing
- cephalexin
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Michigan
Blow-Out Fractures
Reconstruction of Orbital Floor Blow-out Fractures by Titanium Mesh Versus Autogenous Iliac Graft
Blow-out fractures result from direct blunt impacts to the orbit which causes an immediate rise increase in intra-orbital pressure. Decompression via fracture of the orbital floor then occurs.
- Trial name
- NCT07340879
- Testing
- Titanium mesh, autogenous iliac graft
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Face-lift, Facial Rhytidectomy
Efficacy and Safety of FS VH S/D 4 S-apr for Flap Adherence in Rhytidectomy
The purpose of the study is to compare the safety and efficacy of FS VH S/D 4 s-apr versus standard of care in adhering tissue and improving wound healing in subjects undergoing facelift.
- Trial name
- NCT00999141
- Testing
- FS VH S/D 4 s-apr
- Where
- 6 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Burns
Comparison of Wound Bed Establishment in Facial Burns
Forty percent of patients admitted to the contributing regional burn unit over a five month period received facial burns (n=14).
- Trial name
- NCT01668030
- Testing
- Enzymatic agent, Bacitracin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
Injury of Trigeminal Nerve, Surgery
Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve Injury
The purpose of this study is to determine whether sensory retraining exercise could improve lip numbness caused by bilateral sagittal split of mandible.
- Conditions
- Injury of Trigeminal Nerve, Surgery, Mandibular Prognathism
- Trial name
- NCT01586598
- Testing
- sensory retraining protocol
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa Dystrophica, Recessive
A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)
This study is a non-interventional, observational study that will evaluate the natural history of corneal abrasions in patients with Dystrophic Epidermolysis Bullosa (DEB).
- Conditions
- Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa Dystrophica, Recessive, Epidermolysis Bullosa Dystrophica Dominans
- Trial name
- NCT06563414
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Krystal Biotech, Inc.
Inferior Alveolar Nerve Injuries
Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve.
- Trial name
- NCT06270784
- Testing
- Traditional Extraction, Orthodontic Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lip Injury
The Reliability and Versatility of Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of Lip Defects
Nasolabial flaps have limited mobility and may need two stages, mostly for intraoral defects .The facial artery perforator-based flap is the first true perforator flap in the face.
- Trial name
- NCT04974918
- Testing
- Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of large Lip defects post traumatic or post tumor resection.
- Volunteers
- 20 people
- Sponsor
- Sohag University
Mandibular Fracture Trauma, Mandible Fracture
Fixation of Fractures at Anterior Transition Zone Using Three Different Miniplates Configurations
Fractures involving the anterior transition zone of the mandible are frequently encountered and hold particular clinical significance due to the presence of the mental nerve.
- Trial name
- NCT07058597
- Testing
- Twinfork plate, 3D-interlocking plate, Miniplate
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Mandibular Fractures
Erich Arch Bars, IMF Screws and Hybrid Arch Bars in the Management of Mandibular Fractures
Treatment options of mandibular fractures can be accomplished with either closed treatment or open reduction internal fixation (ORIF).
- Trial name
- Jaw Fractures (NCT07153120)
- Testing
- Erich Arch Bars, Hybrid Arch Bars, IMF Screws
- Where
- 2 sites in Egypt
- Volunteers
- 105 people
- Sponsor
- Mansoura University
Facial Injuries, Adipose Tissue
Structural Fat Grafting for Craniofacial Trauma: Repeat Fat Grafting Injection-5 Subject Cohort
Fat grafting represents a technique with great potential to improve outcomes in minimally invasive facial reconstruction. Fat grafting has already been demonstrated as a safe and minimally invasive technique over decades of…
- Trial name
- BTIPlusUp (NCT01822301)
- Testing
- Repeat Fat grafting
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Mandible Fracture
Sagittal Split Plate Versus Two Miniplates in the Treatment of Mandibular Angle Fractures
Mandibular fractures are the second most common maxillofacial fracture after nasal bone fracture. As a result, a lot of research work has gone into improving treatment methods for these fractures including, reduction of…
- Trial name
- NCT07103590
- Testing
- single Sagittal Split plate, two conventional miniplates
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Inferior Alveolar Nerve Injury, Nerve Injury
Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy
Sagittal split osteotomy (SSO) is a common operation done to move the mandible to correct dentofacial deformities and obstructive sleep apnea (OSA).
- Conditions
- Inferior Alveolar Nerve Injury, Nerve Injury, Neurosensory Disorder, Mandibular Nerve Injury
- Trial name
- NCT04706182
- Testing
- Platelet-rich fibrin (PRF), Proximal segment grooving (PSG)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Jesse Han
Trigeminal Neuropathy, Traumatic
Botulinum Toxin Injections for Oral Neuropathic Pain
Peripheral painful traumatic trigeminal neuropathy (PPTTN) are poorly relieved by existing treatments which in addition induce many adverse effects.
- Trial name
- TRIGTOX (NCT03555916)
- Testing
- BOTOX®, Allergan
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Orbital Fractures, Orbital Cellulitis
The Use of Prophylactic Antibiotics in Isolated Blowout Fractures
The purpose of the research is to perform a quality assurance evaluation using randomized prospective analysis the rate of orbital cellulitis as a complication of nonsurgical orbital blowout fracture in patients treated versus…
- Trial name
- NCT01504568
- Testing
- Treatment
- Where
- United States
- Sponsor
- University of Arkansas
Orbital Fractures
Using the Transconjuctival Approach Alone Versus Using it Together With Lateral Canthotomy in Orbital Fractures
All cases will undergo surgery under general anesthesia. Evaluation of patients with suspected orbital fracture should involve radiologic examination, motility test, diplopia field test and exophthalmometry.
- Trial name
- NCT03813732
- Testing
- orbital fracture
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University