Clinical trials: Facial Aging
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Facial Wrinkles, Skin Aging
Anti-Wrinkle Efficacy of a Syringic Acid-Containing Emulsion
This randomized, double-blind, split-face controlled study was conducted to evaluate the anti-wrinkle efficacy and safety of a Syringic acid-containing emulsion in healthy female subjects.
- Trial name
- NCT07850817
- Testing
- Synox-containing Emulsion, Control Emulsion
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BioSpectrum Inc
Facial Skin Aging and Wrinkle Severity
Antioxidant Nutrition and Facial Exercise for Skin Aging
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women.
- Trial name
- NCT07792447
- Testing
- Combined Antioxidant Nutrition and Facial Exercise Program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Aging, Facial Aging
Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study
The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify factors that may influence these changes.
- Trial name
- FaceAge (NCT07719049)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Skin Aging, Facial Aging
Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality
This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis.
- Conditions
- Skin Aging, Facial Aging, Skin Quality
- Trial name
- NCT07466953
- Testing
- Mesenchymal Stem Cell-Derived Exosome
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mert Ersan
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Facial Aging
Evaluating Facial Skin Quality Changes Post-Lipofilling
The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer.
- Trial name
- NCT07737639
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Facial Aging, Rejuvenation
Secretome Treatment for Facial Rejuvenation
Secretome treatment for facial rejuvenation
- Conditions
- Facial Aging, Rejuvenation, Stem Cell, Stem Cell Banking
- Trial name
- NCT07227883
- Testing
- Autologous Hair Follicle-Derived Secretome, Control Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Skin Aging, Skin Hydration
Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis
This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida.
- Conditions
- Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
- Trial name
- SHFA-30-60 (NCT07564869)
- Testing
- BT-Analyze Bioimpedance Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Algeness"
A single-center clinical study of the efficacy and safety of the medical device "Algeness subdermal implant based on agarose (Ghimas SpA/Ghimas SpA, Italy) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Soft Tissue Volume Loss, Lipoatrophy
- Trial name
- NCT07618468
- Testing
- Algeness Subdermal Implant (Agarose)
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Facial Aging, Facial Wrinkles and Rhytides Reduction
Intradermal Microbotulinum Toxin for Sebum Reduction and Facial Pore Improvement
This study aims to evaluate the efficacy and safety of microdoses of botulinum toxin type A (microtoxin) for improving periocular skin quality and reducing fine wrinkles.
- Trial name
- MICROTOX-PORE (NCT07526870)
- Testing
- Botulinum Toxin Type A (Dysport®)
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Facial Aging, Facial Skin Laxity
Safety and Efficacy Evaluation of the Xerf Device for Aesthetic Treatments
The goal of this clinical study is to evaluate the safety and clinical effectiveness of the XERF noninvasive dual-frequency monopolar radiofrequency device for aesthetic improvement of facial aging, including fine lines and…
- Conditions
- Facial Aging, Facial Skin Laxity, Submental and Neck Skin Laxity
- Trial name
- NCT07585591
- Testing
- Noninvasive dual-frequency monopolar radiofrequency
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Facial Skin Laxity, Skin Aging
Focused Ultrasound Treatment for Facial Skin Laxity
The goal of this clinical trial is to learn if focused ultrasound can improve facial skin laxity in adults. The main questions this study aims to answer are: 1.
- Trial name
- NCT07381218
- Testing
- Focused UltrasoundDot Hand-piece (FUS-D), Focused Ultrasound Micro-focused Hand-piece (FUS-M)
- Where
- China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Facial Skin, Motion Capture
Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations
The periorbital region of the face is a critical area affected by aging. Motion Capture (MoCap) allows the precise measurement of the mechanical properties of skin in this region.
- Conditions
- Facial Skin, Motion Capture, Aging, Periorbital Region
- Trial name
- REGARD (NCT07080320)
- Testing
- MoCap
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens