Clinical trials: Facet Joint Pain
Facet Joints; Degeneration, Neuropathy
MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root.
- Conditions
- Facet Joints; Degeneration, Neuropathy, Neuralgia
- Trial name
- NCT01788410
- Testing
- Cryoablation under image guidance, MRI Seednet Cryotherapy System (Galil Medical)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block
In adults with chronic low back pain, the investigators will compare the effectiveness of the medial bundle branch block on three lumbar levels (L3-L4, L4-L5 and L5-S1) performed either by radiographic guidance or by ultrasound…
- Trial name
- NCT04658953
- Testing
- Ultrasound guided infiltration, Fluoroscopy guided infiltration
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Facet Joint Pain
TTAX03 for the Treatment of Lumbosacral Facet Joint Pain
This is a pilot study examining the safety and efficacy of a single intra-articular (IA) injection of TTAX03 per joint to relieve severe spinal facet joint (FJ) pain and improve function in subjects with facet joint pain (FJP) in…
- Trial name
- NCT06236308
- Testing
- TTAX03 10mg, TTAX03 25mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- BioTissue Holdings, Inc
Low Back Pain, Zygapophyseal Joint Arthritis
Endogenous Opioid Response to Injections
This study will study pain relief after spine injections that are used to guide care. Some improvements in pain from a procedure might be from placebo effect rather than the physiological effect of the procedure.
- Trial name
- AEOUI2 (NCT06666621)
- Testing
- Normal saline infusion, Naloxone infusion
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Middle Tennessee Research Institute
Facet Joint Arthritis, Pain
RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain
Rationale: the facet joints are an important pain generator in chronic neck pain. The beneficial effect of radio frequency treatment (RFD) of the cervical facet joints has been described in a Randomized Clinical Trial (RCT) in…
- Conditions
- Facet Joint Arthritis, Pain, Radiofrequency Denervation
- Trial name
- NCT01743326
- Testing
- Radio Frequency Denervation, Local Anesthesia
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- Maastricht University Medical Center
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Chronic Lower Back Pain, Lumbar Facet Syndrome
A Trial of Intravenous Paracetamol vs. Placebo in Patients Receiving Radiofrequency Ablation of the Medial Branch Facet Nerve
A double blinded randomized controlled study comparing pre-procedural IV Paracetamol versus IV placebo (normal saline). The patients will be randomized to either receiving IV paracetamol or saline infusions before undergoing…
- Trial name
- NCT02539979
- Testing
- Paracetamol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Facet Joint Arthropathy, Lower Back Pain
Association Between Trendelenburg Sign and Lumbar MRI Abnormalities
The Trendelenburg sign is a common clinical finding indicating hip abductor dysfunction and altered pelvic stability. The relationship between the Trendelenburg sign, spinopelvic biomechanics, hip muscle strength, and lumbar…
- Trial name
- NCT07629466
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bahçeşehir University
Facet Joint Pain, Back Pain
Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
This is a Phase 2a safety and efficacy study of XT-150 in adult participants experiencing back pain due to inflammation of the facet joint, also known as facet joint osteoarthritis (FJOA), and who are eligible for intra articular…
- Conditions
- Facet Joint Pain, Back Pain, Inflammation
- Trial name
- NCT05196919
- Testing
- XT-150
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Xalud Therapeutics, Inc.
Chronic Pain, Facet Joint Pain
Sensory Mapping of Lumbar Facet Joint Pain
Low back pain is a major contributor to the chronic pain burden in the community. Although there are numerous pain generators in the spine, lumbar facet joints are one of the most common sources of pain.
- Trial name
- SENS-MAP (NCT03323775)
- Testing
- Suprathreshold stimulation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Aberdeen
Joint Pain
Comparison Between Retrolaminar and Medial Branch Block in Cervical Facet Joint Arthropathy
Cervical facet joints have been implicated as a source of chronic pain in 54-67 % patients with chronic posterior neck pain.1 Intraarticular injections, medial branch nerve blocks and neurolysis of medial branch nerves have been…
- Trial name
- NCT05184881
- Testing
- Retrolaminar block, Medial Branch Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Lumbar Facet Joint Pain
One-Needle Vs Three-Needle Radiofrequency in Low Back Pain Due to Facet Joint Arthritis
Failure of RFA has been attributed to technical failure of coagulating the nerve or coagulation of a minimal section of the nerve, allowing for early reinnervation.
- Trial name
- NCT05137652
- Testing
- Radiofrequency ablation of medial nerve using single needle approach, Radiofrequency ablation of medial nerve using three needle approach
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lumbar Facet Joint Pain
MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain
The primary purpose of this protocol is to assess the ExAblate 2100 MR guided high intensity focused ultrasound device as an intervention for treatment of facetogenic lower back pain.
- Trial name
- NCT02291978
- Testing
- ExAblate 2100
- Where
- United States
- Sponsor
- Stanford University
Facet Joint Syndrome
Multifidus Muscle Twitch on the Prognosis of Lumbar Medial Branch RF
The investigators collected data and chart from the patients who were diagnosed facet joint syndrome and underwent lumbar RF medial branch neurotomy between January 2009 and June 2014.
- Trial name
- NCT02580383
- Testing
- Radiofrequency neurotomy of lumbar medial branch
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Severance Hospital
Facet-Mediated Low Back Pain
Allogeneic BM-MSCs in Patients with Lumbar Facet Arthropathy
Researchers are conducting this study to learn more about the side effects of bone marrow-derived stem cells when injected into the facet joints for the treatment of painful lumbar facet joint arthropathies.
- Trial name
- Cellkine (NCT04410731)
- Testing
- Single bilateral intra-articular injection of allogeneic BM-MSCs for lumbar facet joint arthropathy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Pain Measurement
Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints
The emotion Egg, or "eEgg" for short, is a sample series of a device for testing a new pain measurement method that is not yet on the market.
- Trial name
- SMeEgg (NCT05881551)
- Testing
- eEgg, NRS
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University of Witten/Herdecke
Low Back Pain, Osteoarthritis
Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome
The prevalence of low back pain is estimated at 90% . Recent studies have shown that 15% to 52% of back pain is attributable to facet joint syndrome .
- Trial name
- IAPRP (NCT05105256)
- Testing
- Prednisolone, Platelet-rich plasma
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CHU de Reims
Neck Pain Musculoskeletal
Assessing Tissue Response to High-Velocity Thrust Manipulations on Capsule Length and Stiffness at the C5-C6 Facet Joint Capsule
This study is a quasi-experimental study collected quantitative data , with a pre-test-post-test design. Pre-intervention, baseline measurements of C5-C6 right facet joint length and width with the head of the treatment plinth…
- Trial name
- NCT07704853
- Testing
- Long axis trust manipulation C5-C6
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Facet Joint Syndrome
MR-HIFU for Non-invasive Thermal Therapy of Facet-Joint Syndrome:
Patients suffering from facet-joint-syndrome associated with lower-back pain will be treated with MRI-guided High Intensity Focused Ultrasound thermal therapy for pain relief.
- Trial name
- HIFU-FACET (NCT05436873)
- Testing
- MR-HIFU
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Universitätsklinikum Köln