Clinical trials: Facet Joint Arthropathy
Lumbar Spondylosis
Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain
This study is being done to assess the safety of using the Angel Concentrated Platelet Rich Plasma System to process Platelet Rich Plasma (PRP) to treat arthritis of the low back (lumbar spondylosis).
- Trial name
- NCT05250947
- Testing
- Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matthew Pingree
Osteoarthritis, Rheumatoid Arthritis
Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain
This study will assess the outcomes of three currently available regenerative treatments (FloGraft, autologous stem cell therapy, platelet rich plasma therapy) for painful degenerative conditions of the joints.
- Trial name
- NCT01978639
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Arizona Pain Specialists
Facet Joint Arthropathy, Pain
Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy
This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to facet arthropathy…
- Conditions
- Facet Joint Arthropathy, Pain, Osteoarthritis
- Trial name
- NCT06965452
- Testing
- Spinal angiography and embolization/ Embozene Microspheres
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Chronic Low Back Pain, Degenerative Disc Disease
Facet Wedge Post Market Study
A Multi-centre, Prospective, single-arm post market clinical follow up study (PMCF) of the FACET WEDGETM spinal system to assess outcomes in subjects with chronic low back pain due to Degenerative Disc Disease (DDD), facet joint…
- Conditions
- Chronic Low Back Pain, Degenerative Disc Disease, Facet Joint Disease, Pseudo Arthrosis Post Anterior Instrumentation
- Trial name
- NCT02203448
- Testing
- Facet Wedge spinal system
- Where
- 3 sites in Germany, Slovakia
- Volunteers
- 50 people
- Sponsor
- Synthes GmbH
Joint Pain
Comparison Between Retrolaminar and Medial Branch Block in Cervical Facet Joint Arthropathy
Cervical facet joints have been implicated as a source of chronic pain in 54-67 % patients with chronic posterior neck pain.1 Intraarticular injections, medial branch nerve blocks and neurolysis of medial branch nerves have been…
- Trial name
- NCT05184881
- Testing
- Retrolaminar block, Medial Branch Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Low Back Pain
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
- Trial name
- NCT06361485
- Testing
- Lumbar Injections with 10cc's of Wharton's Jelly Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- R3 Stem Cell
Degenerative Lumbar Spinal Stenosis, Facet Joint Arthrosis
Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases
The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Facet Joint Arthrosis, Spondylarthritis, Discopathy
- Trial name
- NCT06320899
- Testing
- SpineShape System IV straight rod elastic, SpineShape System IV straight rod medium, SpineShape System IV straight rod stiff
- Where
- 2 sites in Switzerland
- Volunteers
- 126 people
- Sponsor
- SpineSave AG
Osteoarthritis, Spine
Preliminary Safety and Efficacy of XT-150 in Facet Joint Osteoarthritis
Preliminary safety and efficacy of XT-150 in the synovial capsule of osteoarthritic facet joints in the vertebra of the spine.
- Trial name
- NCT04841512
- Testing
- XT-150
- Where
- Australia
- Sponsor
- Xalud Therapeutics, Inc.
Lumbar Facet Joint Syndrome
The Role of Intra-articular Injection of PRP Versus Corticosteriods in Treatment of Lumbar Facet Disease
Low back pain is an extremely common health problem and recent studies have shown that nearly up to 52% of patients have low back pain caused by lumbar facet joint syndrome.
- Trial name
- PRP (NCT04860531)
- Testing
- Lumbar Facet Joints intra-articular injection with Platelet Rich Plasma, Lumbar Facet Joints intra-articular injection with a mixture of 0.5% lidocaine and 5mg/ml of betamethasone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Low Back Pain
Effectiveness of Facet Joint Infiltration in Low Back Pain
The purpose of this study is to evaluate the effectiveness of facet joint infiltration with corticosteroids in the treatment of low back pain due to facet joint osteoarthritis.
- Trial name
- NCT01447160
- Testing
- Cortisone
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Low Back Pain, Lumbar Facet Joint Pain
An Alternative Technique for Lumbar Medial Branch Radiofrequency: Comparison With the Empirical Technique
In spite that variable techniques for lumbar MBRF exists, the tunnel vision technique is widely recommended for exact radiofrequency needle placement.
- Conditions
- Low Back Pain, Lumbar Facet Joint Pain, Arthropathy
- Trial name
- MBRF LBP (NCT01300715)
- Testing
- lumbar medial branch radiofrequency neurotomy
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Spinal Stenosis, Spinal Disease
Percutaneous Trans-facet Screw Fixation Under CT-scan Guidance for Remaining Symptoms at a Distance of Previous Spinal Surgery
Background : Segmental spinal instability after a laminectomy, and adjacent segment disease (ASD) at after an arthrodesis, are well-known concerns in spinal surgery, which may require re-interventions, usually by surgical…
- Conditions
- Spinal Stenosis, Spinal Disease, Zygapophyseal Joint Arthritis, Joint Instability
- Trial name
- NCT05525052
- Testing
- Trans-Facet fixation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Neck Pain, Cervical Facet Arthropathy
The Specificity of Cervical Facet Medial Branch Blocks
Cervical facet arthropathy is a common cause of chronic neck pain. The "gold standard" for diagnosis is either blocking the facet joints, or more commonly blocking the medial branch nerves that innervate the joints.
- Trial name
- NCT00613340
- Testing
- Cervical medial branch blocks
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Lower Back Pain Chronic, Facet Joint Arthrosis
Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
The goal of this clinical trial is to compare low-dose radiation therapy (LDRT) with intra-articular steroid injections in participants suffering from chronic lower back pain as cause of facet joint arthritis (FJA).
- Conditions
- Lower Back Pain Chronic, Facet Joint Arthrosis, Osteoarthritis, Spine
- Trial name
- LORAFA (NCT05852808)
- Testing
- Intra-articular steroid injections, Low-dose radiation therapy
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Silvia Gomez Ordonez
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Facet Joint Arthropathy, Lower Back Pain
Association Between Trendelenburg Sign and Lumbar MRI Abnormalities
The Trendelenburg sign is a common clinical finding indicating hip abductor dysfunction and altered pelvic stability. The relationship between the Trendelenburg sign, spinopelvic biomechanics, hip muscle strength, and lumbar…
- Trial name
- NCT07629466
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bahçeşehir University
Lumbar Fusion Surgery, Fusion of Joint
Evaluation of the Efficacy and Safety of Absorbable vs Traditional Bone Wax for Facet Fusion After Lumbar Fusion Surgery
Hemorrhage on the surface of cancellous bone presents a significant challenge in orthopedic surgery. Traditional bone wax, commonly utilized for hemostasis in bone wounds, is non-absorbable and associated with various…
- Trial name
- NCT07040293
- Testing
- Absorbable bone wax for hemostasis in the osteotomy surface of the facet joint, Traditional bone wax for hemostasis in the osteotomy surface of the facet joint
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shanghai Changzheng Hospital