Clinical trials: FRNS/SDNS, active
Nephrotic Syndrome in Children, Telitacicept
Study of the Telitacicept in Pediatric Patients With Frequently Relapsing or Steroid Dependent Nephrotic Syndrome
The main objective is to evaluate the effectiveness of telitacicept in pediatric patients with frequently relapsing or steroid dependent nephrotic syndrome within the 52-week follow-up.
- Trial name
- STERN (NCT06125405)
- Testing
- Telitacicept
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Nephrotic Syndrome in Children, Nephrotic Syndrome Steroid-Dependent
Dupilumab Therapy in Nephrotic Syndrome in Children
The goal of this clinical trial is to learn if dupilumab works to treat severe nephrotic syndrome in children. It will also learn about the safety of dupilumab.
- Trial name
- SMART-NS (NCT07091175)
- Testing
- Dupilumab, Co-intervention of Prednisolone wean during randomised controlled phase, Dupilumab open label extension phase
- Where
- 2 sites in Singapore
- Volunteers
- 66 people
- Sponsor
- National University Hospital, Singapore
FRNS/SDNS, Ripertamab
Study of Ripertamab in Children With Frequent Relapses or Steroid-Dependent Nephrotic Syndrome
This is an open-label randomized controlled trial to evaluate the efficacy and safety of one dose versus two doses of ripertamab in children with frequent relapses or steroid-dependent nephrotic syndrome (FRNS/SDNS).
- Trial name
- NCT07388810
- Testing
- ripertamab
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Mao Jianhua
Nephrotic Syndrome in Children
Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.
Primary nephrotic syndrome accounts for approximately 90% of the total number of nephrotic syndrome in childhood and it is the most common glomerular disease in children.
- Trial name
- NCT06079788
- Testing
- Adrenocorticotrophic Hormone, Steroid
- Where
- 8 sites in China
- Volunteers
- 140 people
- Sponsor
- Mao Jianhua