Clinical trials: Extubation
Thyroid Diseases
Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
Thyroid surgery requires smooth emergence from anesthesia to minimize coughing, hemodynamic fluctuations, and agitation during extubation, which may contribute to postoperative complications such as bleeding or cervical hematoma.
- Trial name
- DEX-THYROID (NCT07462195)
- Testing
- Dexmedetomidine, Standard General Anesthesia
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Bach Mai Hospital
Respiratory Failure
Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure
The aim of this study was to compare the indices of rapid shallow breathing, neuromechanical efficiency (NME), and neuroventilatory efficiency (NVE) between patients being successfully extubated and those who failed weaning.
- Trial name
- NCT01065428
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Southeast University, China
Oral Infection
Prediction Model for Delayed Extubation of Tracheal Intubation in Patients With Maxillofacial Space Infection After Abscess Incision and Drainage Surgery
Retrospective exploration of the risk factors associated with mechanical ventilation and tracheal extubation twenty-four hours after abscess incision and drainage surgery in patients with maxillofacial space infection.
- Trial name
- Prediction mod (NCT06853808)
- Volunteers
- 400 people
- Sponsor
- Henan Provincial People's Hospital
Extubation, Respiratory Complications
Extubation Criteria in Patients Greater Than 59 Years of Age
Prospectively evaluate the predictive value of individual pre-specified clinical extubation criteria for extubation success
- Trial name
- NCT04596735
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- Wake Forest University Health Sciences
Prediction of Extubation Readiness
Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior
The investigators hypothesize that machine learning methods using a combination of novel, quantitative measures of cardio-respiratory variability can accurately predict the optimal time to extubate extreme preterm infants.
- Trial name
- NCT01909947
- Testing
- Cardiorespiratory signal acquisition
- Where
- 5 sites in United States, Canada
- Volunteers
- 266 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Coronary Artery Bypass
Oropharyngeal Humidification After Extubation on Thirst
In patients who have undergone endotracheal intubation following cardiac surgery, symptoms such as thirst, dysphagia (difficulty swallowing), restlessness, nausea, and vomiting are frequently observed, and these conditions…
- Trial name
- NCT07397221
- Testing
- Oropharyngeal Humidification with Water Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Muş Alparslan University
Respiratory Failure, Mechanical Ventilation
External Validation of AI-Aided Weaning Software Using Multicenter Retrospective Data
This multicenter retrospective study aims to externally validate an artificial intelligence-aided weaning software developed using intensive care unit data from Taichung Veterans General Hospital between 2015 and 2019.
- Conditions
- Respiratory Failure, Mechanical Ventilation, Critical Illness
- Trial name
- NCT07658131
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- Taichung Veterans General Hospital
Infant, Premature, Diseases, Infant, Newborn, Disease
Noninvasive High Frequency Oscillatory Ventilation as a Post-extubation Respiratory Support in Neonates
A randomized controlled trial comparing Noninvasive high frequency oscillatory ventilation (NHFOV) and Noninvasive positive pressure ventilation (NIPPV) as post-extubation respiratory support in preterm neonates with respiratory…
- Conditions
- Infant, Premature, Diseases, Infant, Newborn, Disease, Respiratory Tract Diseases, RDS
- Trial name
- NCT05493527
- Testing
- noninvasive high frequency oscillatory ventilation, noninvasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cardiac Surgery
Randomized Evaluation of Operating Room Extubation After Cardiac Surgery
We are studying whether waking patients up and removing the breathing tube (also known as "extubation") in the operating room after cardiac surgery improves postoperative recovery without causing harm.
- Trial name
- NCT07757880
- Testing
- OR extubation, ICU extubation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Cough, Anesthesia
Efficacy of Remifentanil Compared to Lidocaine on the Incidence of Coughing During Emergence of Anesthesia
This study is designed to compare the effects of a bolus dose of remifentanil to a bolus dose of lidocaine given prior to the emergence of anesthesia: on the incidence of perioperative coughing on the time needed for the…
- Conditions
- Cough, Anesthesia, Extubation
- Trial name
- NCT01026129
- Testing
- Remifentanil, lidocaine
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Anesthesia Complication
Perioperative Complications of Deep Extubation in Adults
The investigators propose a prospective observational cohort study in order to investigate the perioperative respiratory complications of deep extubation in adults undergoing eye and head-and-neck surgery at Massachusetts Eye and…
- Trial name
- NCT04557683
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
PreTerm Neonate, Sedation for Invasive Mechanical Ventilation
Efficacy of Dexmedetomidine Versus Midazolam Sedation on Extubation Time in Mechanically Ventilated Preterm Infants
Very preterm neonates (born before 32 weeks' gestation) often require invasive mechanical ventilation (IMV) to manage respiratory insufficiency.
- Conditions
- PreTerm Neonate, Sedation for Invasive Mechanical Ventilation, Very Preterm Neonates With Sedation for Invasive Mechanical Ventilation
- Trial name
- DEXPRE (NCT06878703)
- Testing
- Midazolam, Dexmedetomidine
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris