Clinical trials: Extremity Injury
Wounds, Wounds and Injuries
Pilot Trial for WounDx™ Clinical Decision Support Tool
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital.
- Conditions
- Wounds, Wounds and Injuries, Extremity Injury, Traumatic Wounds and Injuries
- Trial name
- NCT06921707
- Testing
- Clinical Decision Support Tool, Standard of Care (SOC)
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Athletic Injuries, Soccer Injury
FIFA 11+ Warm-Up and Injury Risk Classification in Youth Amateur Soccer Players
This randomized controlled trial evaluated whether an eight-week, supervised FIFA 11+ neuromuscular warm-up program improves multifactorial injury risk classification, functional performance, and time-loss injury incidence in…
- Conditions
- Athletic Injuries, Soccer Injury, Lower Extremity Injury, Sprains and Strains
- Trial name
- NCT07713004
- Testing
- FIFA 11+ Neuromuscular Warm-Up Program, Routine Warm-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Basketball Performance, Sports Injury Risk
Position-Specific Lower Limb Performance and AI-Based Injury Risk Analysis in Young Male Basketball Players
This observational study aims to evaluate lower extremity performance characteristics in young male basketball players according to their playing positions and to explore injury risk patterns using artificial intelligence…
- Conditions
- Basketball Performance, Sports Injury Risk, Lower Extremity Performance, Athletic Performance
- Trial name
- NCT07677371
- Testing
- Lower Extremity Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers
Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds
Use of a motorized waterjet to debride wounds to improve healing outcomes.
- Conditions
- Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries
- Trial name
- NCT07653165
- Testing
- Motion NPWT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Boca Center for Wound Healing
Upper Extremity Injury, Upper Extremity Deformities, Congenital
SoftHand Comparison Study
A trial to compare the performance of the SoftHand Pro (SHP) and Ossur i-Limb in people with transradial limb loss over an 8-week period.
- Conditions
- Upper Extremity Injury, Upper Extremity Deformities, Congenital, Amputation, Traumatic, Amputation, Congenital
- Trial name
- NCT05328934
- Testing
- SoftHand Pro, Ossur i-Limb
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Extremity Injury
Pre-hospital Tourniquet in Extremity Injury
2.1. Objective: Primary Objective: To compare outcomes of patients with extremity injuries presenting with or without pre-hospital tourniquet placement. 2.2.
- Trial name
- NCT04216225
- Testing
- pre-hospital tourniquet placement
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Methodist Health System
Tissue Perfusion, Lower Extremity Surgery
Comparison of the Effects of General Anesthesia and Spinal Anesthesia on Tissue Perfusion in Patients Undergoing Lower Extremity Surgery
This prospective, single-center observational study compares the effects of general anesthesia and spinal anesthesia on tissue perfusion in patients undergoing lower extremity surgery with tourniquet use.
- Conditions
- Tissue Perfusion, Lower Extremity Surgery, Tourniquet-Induced Ischemia-Reperfusion Injury, General Anesthesia
- Trial name
- Perf-LEX (NCT07474480)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Lower Extremity Injury
Cohort Study of PPP Injections for Athletes With Muscle Injury
The investigators hypothesize that a single injection of platelet-poor plasma (PPP) into an acute muscle injury will significantly improve local muscle regeneration and patient outcomes compared to the standard of care using only…
- Trial name
- NCT07566039
- Testing
- Platelet Poor Plasma (PPP) Injection
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Surgical Wound, Upper Extremity Injury
Suture Closure Trial
Closure of surgical incisions in orthopedic procedures contributes to patient postoperative pain and risk of complication. As the focus on improving orthopedic surgery outcomes shifts to best practices in postoperative pain…
- Trial name
- NCT05261425
- Testing
- Monocryl buried, Nylon (FDA Approved) not buried
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Emory University
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Lower Extremity Musculoskeletal Injury
Evaluation of Lower Extremity Athletic Injuries and Response to Treatment Using SWE and MFI
Primary Objective: To explore changes in shear wave elastography (SWE) and microvascular flow imaging (MFI) measurements from time of injury through the recovery phase of lower extremity musculoskeletal injuries to determine if a…
- Trial name
- NCT05608824
- Testing
- Shear wave elastography and microvascular flow imaging.
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
- Trial name
- NCT06991205
- Testing
- Web-TIRELESS, Web-MEUC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jafar Bakhshaie
Lower Extremity Problem, Musculoskeletal Injury
Adolescent Normative Sport Movement Analysis
The objective of this study is to collect baseline data from a normative population of adolescents who participate in organized "land-based" sports, that gender and age matches some of the population of patients expected to be…
- Trial name
- NCT05068544
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- MultiCare Health System Research Institute
Fractures, Open, Wounds and Injuries--Infections
Acute Application of Antibiotic Powder in Open Fracture Wounds
The purpose of this study is to help determine the best treatment for severe injures like open fracture wounds. Some broken bone injuries can be more likely to get an infection. It is mostly due to the way they were injured.
- Conditions
- Fractures, Open, Wounds and Injuries--Infections, Anti-Bacterial Agents, Fractures, Bone
- Trial name
- APOW (NCT04872400)
- Testing
- Vancomycin, Tobramycin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries, Upper Extremity Paresis
Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries
Texas Biomedical Device Center at UT Dallas has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT).
- Trial name
- NCT04288245
- Testing
- Active Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Cellular Injury and Post-Cryogenic Recovery, Cryogenic Cellular Stress
Evaluation of In-Vitro Cryo Therapeutic Protocols on Human Cell Samples (TWH-CRYO-001)
This laboratory-based study evaluates the effects of controlled cryogenic preservation on human cell samples using Truway Health's in-vitro cryo therapeutic methodology.
- Conditions
- Cellular Injury and Post-Cryogenic Recovery, Cryogenic Cellular Stress, Cold-Induced Cellular Injury, Thermal Injury Response
- Trial name
- CRYO-IVT (NCT07321028)
- Testing
- Standard Laboratory Cryopreservation Procedure, Enhanced Laboratory Cryopreservation Procedure, Normothermic Cell Culture Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Truway Health, Inc.
Pain, Procedural, Analgesia
Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department
The goal of this observational study is to evaluate the effectiveness and safety of different procedural sedation and analgesia methods used for adults with painful fractures requiring reduction treatment in the emergency…
- Conditions
- Pain, Procedural, Analgesia, Extremity Injury, Patient Satisfaction
- Trial name
- PAINEX (NCT07314450)
- Testing
- Usual Care
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Region Zealand
Lower Extremity Injuries
Prediction of Lower Extremity Injuries Using Lower Limb-worn Inertial Measurement Units
This study analyses questionnaires and inertial sensor data from 108 sports science students regarding previous lower extremity injuries, sports activity, and preventive measures, combined with the prospective development of an…
- Trial name
- PredKnee (NCT07289828)
- Testing
- IMU Data collection, Questionnaire
- Where
- Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich