Clinical trials: Exposure to Environmental Pollution
Healthy Participants
Wildfire Related Air Pollution Exposure and Cognitive Function Pilot Study
This study will examine how breathing wildfire-related air pollution (WRAP) for one hour affects healthy adults. The main question the study will answer if the effect of WRAP exposure on p-tau, a blood marker of cognitive…
- Trial name
- WRAP (NCT07151235)
- Testing
- Simulated wildfire smoke exposure, Clean Air exposure
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Exposure to Environmental Pollution
Impact of Exposure to Environmental Pollutants on Birth Outcomes in an Israeli Cohort
Objectives and hypothesis The scale and diversity of chemicals in worldwide use today is vast. Many of these chemicals are released into the environment where they are found in air, water, soil, house dust, and in the food…
- Trial name
- NCT03084445
- Where
- 3 sites in Israel
- Volunteers
- 2,394 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Sleep, Pollution; Exposure
Investigating the Effect of Daily CARDIO® Capsules Supplementation on Improved Sleep in Healthy, Urban-Dwelling Adults
This study aims to explore the impact of supplementation with CARDIO® whole salmon oil capsules on healthy adult participants with sleep disruption related to particulate matter pollution.
- Conditions
- Sleep, Pollution; Exposure, Cough
- Trial name
- NCT06768970
- Testing
- CARDIO® salmon oil
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Environmental Tobacco Smoke Exposure, Depression
Healthy Outcomes of Pregnancy Education
The purpose of this study is to determine if an integrated intervention addressing active smoking, environmental tobacco smoke exposure, depression and intimate partner violence, would improve pregnancy outcome among African…
- Conditions
- Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
- Trial name
- NCT00381823
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Idiopathic Pulmonary Fibrosis, Pulmonary Disease
Influence of Socioeconomic and Environmental Factors on the Natural History of Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis(IPF) is the most common idiopathic interstitial lung disease whose cause is unknown. With age and gender, socio-economic factors are the most influential indicators of health.
- Conditions
- Idiopathic Pulmonary Fibrosis, Pulmonary Disease, Pulmonary Medicine
- Trial name
- EXPOSOMFPI (NCT04619199)
- Testing
- Blood sample
- Where
- 16 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Exposure to Pollution
Chemometers to Determine the Environmental and Human Exposome by Mixtures of Pollutants
Motivation of this study Human life is full of chemicals: They support the provision of cure, clothes, shelter, transportation and even nourishment of the world population.
- Trial name
- EXPOSO-METER (NCT05927077)
- Testing
- planned surgery for weight reduction
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helmholtz Centre for Environmental Research - UFZ
Pollution; Exposure
Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water
Approximately 34 million Americans rely on private wells to supply their drinking water. Private wells are excluded from the Safe Drinking Water Act.
- Trial name
- NCT05395663
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Exposure to Environmental Pollution, Non-occupational
The Interaction of Social Factors With Air Pollution
Purpose: The purpose of this protocol is to understand how social factors such as psychosocial stress may modify how people respond to air pollution.
- Trial name
- SOZIAL (NCT02206750)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Pollution; Exposure
Effect of an Oral Acerola Juice Powder on Skin Beauty Parameters in Women Exposed to Environmental Stresses
The study is being conducted to evaluate the efficacy and the safety of an oral acerola-based product on skin ageing parameters.
- Trial name
- NCT07229131
- Testing
- Acerola Juice Powder 1200 mg/day, Acerola Juice Powder 600 mg/day
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Diana SAS
Allergic Rhinitis, Allergic Asthma
Environmental Pollutants and Their Effects on Respiratory Allergy
In Latin America and the Caribbean, more than 100 million people are exposed to higher levels of pollution than those recommended by WHO.
- Conditions
- Allergic Rhinitis, Allergic Asthma, Pollution; Exposure
- Trial name
- NCT04902989
- Testing
- pollutants and pollen
- Where
- Mexico
- Volunteers
- 93 people
- Sponsor
- Cindy Elizabeth de Lira-Quezada
Cardiovascular Diseases, Particulate Matter Inhalation Injury
Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.
The purpose of this study is to determine the impact of individually lifetime accumulated exposure to air and noise pollution on the incidence and prevalence of cardiovascular diseases (CVD) and mortality.
- Conditions
- Cardiovascular Diseases, Particulate Matter Inhalation Injury, Arteriosclerosis, Pollution; Exposure
- Trial name
- AIRCARD (NCT04353232)
- Where
- Denmark
- Volunteers
- 33,723 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Vapors; Inhalation, Cancer
Addressing Tetrachloroethylene Exposure in an Impacted Community
Groundwater in Martinsville, IN, is contaminated by volatile organic compounds (VOCs), tetrachloroethylene (PCE) and trichloroethylene (TCE).
- Conditions
- Vapors; Inhalation, Cancer, Volatile Organic Compounds
- Trial name
- NCT05819996
- Testing
- Environmental educational campaign
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- Purdue University
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Lung Diseases, Cancer
Modulation of Benzene Metabolism by Exposure to Environment
The research is to evaluate benzene metabolism after exposure at levels that can be found in the environment, such as the higher end concentrations in the air inside cars and buses while being driven in heavy traffic and inside…
- Trial name
- NCT00041860
- Testing
- Controlled Exposure to Environmental Contaminant
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Noise Exposure, Environmental Exposure
The Social Gradient of Urban Noise Pollution and Its Effect on Pediatric and Adult Health
The investigators pilot test an intervention to understand the spatial-temporal distribution of aggregated environmental noise exposure in Philadelphia and its impact on health.
- Conditions
- Noise Exposure, Environmental Exposure, Health Behavior
- Trial name
- NCT04822155
- Sponsor
- University of Pennsylvania
Environmental Exposure, Nasal Inflammation
Human Biological Responses to Low Level Ozone
To investigate if low level ozone exposure will cause measurable inflammation in nasal cells.
- Trial name
- SNOZ (NCT02857283)
- Testing
- Ozone, Filtered Air, Health and Exposure Tracker (HET)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Second Hand Smoke, Exposure to Environmental Pollution
The Effect of a Zero Tolerance Program (SToP) on Child's Urine Cotinine Level According to Exposure Feedback
Although the ban on indoor smoking has greatly reduced secondhand smoke (SHS) exposure in public spaces, the home environment is still the primary source of exposure to SHS, particularly in children under the age of five.
- Conditions
- Second Hand Smoke, Exposure to Environmental Pollution, Child, Urine
- Trial name
- SToP (NCT05545748)
- Testing
- Zero (0) Tolerance Program (SToP), Exposure Feedback Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Healthy Volunteer
Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
The SEPAGES couple-child cohort is coordinated by an Inserm (French National Institute of Health and Medical Research) team of environmental epidemiology.
- Trial name
- SEPAGES-1337 (NCT02852499)
- Testing
- Urine sampling, Carry a GPS and BET, Carry pollution sensor
- Where
- France
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble