Clinical trials: Experience
Clinical Safety of a PBM Program
The German Patient Blood Management Network
This epidemiological trial will determine whether the implementation of a PBM program is safe and effective in terms of clinical outcome compared to a pre-implementation cohort Primary endpoint is a composite outcome comprising…
- Trial name
- NCT02147795
- Where
- 2 sites in Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Coronary Artery Disease
The IRIS-Resolute Integrity (IRIS-Integrity)
This is a prospective, observational, cohort study to evaluate the relative efficacy and safety of Resolute Integrity stent compared to other (drug eluting stents) DES.
- Trial name
- NCT01392846
- Where
- 23 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Seung-Jung Park
Social Isolation, Health Services Accessibility
Optimizing Medical Decisions and Care for Adult Orphans
This study aims to evaluate the effectiveness of a training program designed to improve clinicians' ability to care for adult orphans.
- Trial name
- NCT07465770
- Testing
- Caring for Adult Orphans
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Orthodontic Patient Experience
Orthodontic Patient Experience of Intraoral Scans Versus Alginate Impressions
CONTEXT: Digital scanning systems are becoming more and more popular with the advent of the COVID-19 pandemic. The risks surrounding aerosol-generating procedures (AGP) has resulted in practitioners changing their normal practice…
- Trial name
- OPESI (NCT05194956)
- Testing
- Intraoral scan, Alginate impressions
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Cutaneous Melanoma, Cutaneous Melanoma, Stage III
Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma
The introduction of immune checkpoint inhibitors (ICIs) for the treatment of patients with stages IIB to IV cutaneous melanoma resulted in dramatic improvements in mortality rates for this common form of cancer.
- Conditions
- Cutaneous Melanoma, Cutaneous Melanoma, Stage III, Cutaneous Melanoma by AJCC V7 Stage, Cutaneous Melanoma, Stage IV
- Trial name
- NCT07148245
- Testing
- Blood Sample, Health Related Quality of Life Questionnaires (HRQoL), Medical Chart Review
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Continuous Glucose Monitoring, Diabetes Mellitus
A Study to Learn How Well a Monitoring System Called Continuous Glucose Monitoring (CGM) Which Measures Glucose on an Ongoing Basis Works and How Safe it is in Chinese Patients in Usual Practice
Researchers are looking for a better way to help Chinese people who have diabetes to monitor their blood sugar (blood glucose) situation. There are 2 types of diabetes.
- Trial name
- CareMins (NCT05038761)
- Testing
- CGM System, Standard Venous Blood Glucose Test
- Where
- 2 sites in China
- Volunteers
- 76 people
- Sponsor
- Bayer
Insomnia
Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication
Sleep related disorders are common in primary care practice. Sleep wear related data has not been utilized to improve sleep related communication between patients and providers.
- Trial name
- NCT03795129
- Testing
- SleepLife Application w/FitBit, FitBit w/Minimal to No SleepLife App.
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Regenstrief Institute, Inc.
Stress Reduction
AI-Guided Stress Management Breathing Practices Via a Wearable Device
This study explores the effectiveness of AI-guided breathing practices for stress management in adults. In this randomized controlled trial, 120 participants will be recruited and assigned to an intervention group (n=90) or a…
- Trial name
- NCT06881875
- Testing
- AI-guided breathing practices, Progressive muscle relaxation
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University
Preventive Services, Immunizations
Delivery of Preventive Services in Primary Care
The major goal of this project is to determine the effectiveness of a multi-component intervention designed to help primary care practices implement three office system strategies known to increase delivery of immunizations and…
- Conditions
- Preventive Services, Immunizations, Screening
- Trial name
- NCT00115557
- Testing
- Practice intervention, Practice intervention 2
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Knowledge, Attitude to Health
Comparing the Effect of Online and Conventional Oral Health Education in Egypt
This study aims to compare the results of online oral health education and conventional oral health education methods in terms of their effectiveness towards improving the knowledge and practice of oral hygiene in primary school…
- Conditions
- Knowledge, Attitude to Health, Practice
- Trial name
- NCT05570500
- Testing
- Oral health education
- Where
- Egypt
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Health Knowledge, Attitudes, Practice
Can the Prediction Market Improve Predictions of COVID-19?
The goal of this study is to better understand how people predict the future risks of the novel Coronavirus (COVID-19). Specifically, the investigators will ask the following research questions: How well do participants predict…
- Trial name
- NCT04410692
- Testing
- Prediction Market
- Where
- Singapore
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Rheumatoid Arthritis
Observation of Treatment With Certolizumab Pegol in Daily Practice
This is an observational, non-interventional, non-comparative, post-authorization safety study to evaluate efficacy and long-term safety of Cimzia in adult patients with RA in need of treatment with a biological product.
- Trial name
- FasT (NCT01069419)
- Where
- 163 sites in Germany
- Volunteers
- 1,117 people
- Sponsor
- UCB Pharma GmbH
Evidence-Based Practice, Labor; Prolonged, Second Stage
Open-glottis Pushing Technique Versus the Valsalva Pushing Technique in the Second Stage of Labor
Pushing has been discussed for decades, primarily in terms of facilitating care in the second stage of labor and maternal/fetal outcomes. Valsalva-type pushing is the pushing performed by a pregnant woman by holding her breath.
- Conditions
- Evidence-Based Practice, Labor; Prolonged, Second Stage, Labor, Fetal Acidosis Complicating Labor and Delivery
- Trial name
- NCT06210087
- Testing
- Spontaneous pushing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Urinary Incontinence
A Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence
The main goal of this clinical trial is to improve the care for urinary incontinence (UI) provided to adult women by primary care providers.
- Trial name
- OPTIMA (NCT05534412)
- Testing
- Academic Detailing, Electronic Clinical Decision Support, APP Co-management
- Where
- 4 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Calculus; Gallbladder, With Cholecystitis
Two Institutes Experience in Laparo-Endoscopic Rendezvous Technique for Gallbladder and Bile Duct Stones
The management of gallbladder stones (lithiasis) concomitant with bile duct stones is controversial. The management of CBD stones has evolved considerably since the advent of laparoscopic surgery.
- Trial name
- NCT05734144
- Testing
- The intraoperative ERCP has been performed immediately before LC, POES followed by LC
- Volunteers
- 432 people
- Sponsor
- Zagazig University
NonValvular Atrial Fibrillation
Eliquis Regulatory Post Marketing Surveillance
The primary objective of this study is to examine the safety profile of Eliquis in Korean nonvalvular atrial fibrillation patients.
- Trial name
- NCT01885598
- Testing
- Apixaban
- Where
- South Korea
- Volunteers
- 3,335 people
- Sponsor
- Bristol-Myers Squibb
Periodontitis, Periodontal Diseases
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- PAAS (NCT06131021)
- Testing
- Amoxicillin, Metronidazole
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Multiple Sclerosis
Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot Drop
People with Multiple Sclerosis (pwMS) often experience 'foot-drop' which means that the foot is not adequately lifted during the so-called swing phase (foot is off the ground) during walking which can lead to trips and falls.
- Trial name
- NCT01914016
- Testing
- prolonged walk
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen Margaret University
COVID - 19, Multiple Sclerosis
COVID-19 Knowledge, Attitudes, Practices and Perceived Risk: Cross Sectional Mixed Methods
Knowledge, attitudes, behaviors and perceived risk highlight the importance of education translated into actions to reduce the risk of global infections.
- Trial name
- Coronavirus (NCT07021716)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Blood Stem Cell Harvest Failure
Peripheral Blood CD34-positive Cells Enumeration as Predictor of Stem Cell Harvest
Stem cell mobilization procedures after chemotherapy and G-CSf performed at our Institution between 2002 and 2013 were reviewed in order to define prognostic factors for optimal harvest
- Trial name
- NCT02023814
- Volunteers
- 250 people
- Sponsor
- Ospedale Santa Croce-Carle Cuneo