Clinical trials: Exotropia
Strabismus, Nystagmus, Congenital
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus.
- Trial name
- NCT04770519
- Testing
- whole genome sequencing or whole exome sequencing
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Exotropia Intermittent
Base-in Prism Spectacles for Intermittent Exotropia
The objective of this short-term, pilot randomized trial comparing spectacles with relieving prism to spectacles without prism is to determine whether to proceed to a full-scale, longer-term randomized trial.
- Trial name
- IXT6 (NCT03998670)
- Testing
- Prism Glasses, Non-Prism Glasses
- Where
- 28 sites in United States
- Volunteers
- 61 people
- Sponsor
- Jaeb Center for Health Research
Consecutive Exotropia, Medial Rectus Advancement
Surgical Management of Consecutive Exotropia : Surgical Choice Based on the Angle of Deviation
Aim of the work: to have a surgical plan for consecutive exotropia based on the degree of the angle of deviation. Setting: Department of ophthalmology, Faculty of medicine, Minia University, Egypt.
- Trial name
- NCT07848139
- Testing
- patients with angle of deviation of 30 PD or less had undergone bilateral lateral rectus recession
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Exotropia Equal or More Than 50 Prism Diopter
A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia
This is a randomized comparative interventional study that aims to compare the surgical outcomes of correcting large angle exotropia (≥50 prism diopter) by three different surgical techniques including: 1/ bilateral lateral…
- Trial name
- NCT07143032
- Testing
- Extropia squint surgery
- Volunteers
- 60 people
- Sponsor
- Sohag University
Strabismic Deviation, Strabismus
Botulinum Toxin for Strabismus Treatment
The bacterial species Clostridium botulinum produces a class of neurotoxins known as botulinum toxin. At the neuromuscular junction, botulinum toxin A prevents acetylcholine from being released.
- Trial name
- Botox Squint (NCT07180394)
- Testing
- Botox injection into extraocular muscles
- Where
- Pakistan
- Volunteers
- 127 people
- Sponsor
- Foundation University Islamabad
Exercise Training, Intermittent Exotropia
Exercise Training on a Mirror for Intermittent Exotropia Control Post Strabismus Surgery
The study aims to explore the impact of mirror therapy on exodeviation control, near and far strabismus angles, and quality of life in intermittent exotropia control post strabismus surgery, as well as its effects on near and far…
- Conditions
- Exercise Training, Intermittent Exotropia, Strabismus
- Trial name
- NCT06762067
- Testing
- mirror therapy, traditional therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Exotropia
Comparison of Medial Rectus Resection and Plication in Exotropic Patients
Purpose: To determine the surgical outcomes of the plication technique in comparison with the resection method on exotropic patients.
- Trial name
- NCT03768362
- Testing
- Plication strabismus surgery, Resection strabismus surgery
- Volunteers
- 52 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Strabismus, Esotropia
Bupivacaine Injection of Eye Muscles to Treat Strabismus
This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus.
- Conditions
- Strabismus, Esotropia, Exotropia, Graves Disease
- Trial name
- NCT01616108
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Smith-Kettlewell Eye Research Institute
Strabismus, Noncomitant
Muscle Transplantation in Strabismus Surgery
All the patients underwent standard muscle transplantation, where the resected extra stump of lateral or medial rectus muscle was transplanted to the medial or lateral rectus muscle using 6-0 prolene which wasrecessed by a…
- Trial name
- NCT05827393
- Testing
- muscle transplantation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- South Valley University
Intermittent Exotropia, Myopia
A Comparative Study of the Efficacy of Myopia Control Lenses With Different Mechanisms on Controlling Myopia Progression in Patients With Intermittent Exotropia
The goal of this clinical trial is to compare the efficacy of myopia control lenses with different working principles in patients with intermittent exotropia aged 6 to 12 years.
- Trial name
- NCT07642934
- Testing
- DIMS glasses, DOT glasses
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intermittent Exotropia, Visual Functions
Visual Training for Improving Intermittent Exotropia Visual Function
The goal of this clinical tral is to investigate that if VR/AR visual training can improve the visual function in children with intermittent exotropia.
- Trial name
- NCT06594666
- Testing
- VR/AR visual training group
- Volunteers
- 78 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Exotropia
Study of Clinical Types and Surgical Out Come of Pediatric Exotropia
study aiming to evaluate all children presented to strabismus clinic in ophthalmology department at sohag university hospital with divergent squint (exotropia) and to record surgical outcome of those who underwent strabismus…
- Trial name
- NCT05089422
- Testing
- Squint surgery
- Volunteers
- 30 people
- Sponsor
- Sohag University
Moderate Intermittent Exotropia
Study of Surgical Treatment Versus Observation in Children With Moderate Intermittent Exotropia
The purpose of this study is to determine the long-term effect and security of the surgical treatment and observation only on ocular alignment, binocular stereopsis, and quality of life in children with moderate intermittent…
- Trial name
- SOMIX (NCT02736526)
- Testing
- recession or resection of the horizontal extraocular muscles
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sun Yat-sen University
Complications
Surgery and Convergence Insufficiency Intermittent Exotropia
This trial aims to determine which treatment modality is better for treatment of the convergence insufficiency subtype of intermittent exotropia.
- Trial name
- NCT01435876
- Testing
- Post exercise Surgery, Orthoptics, Postop orthoptics
- Where
- 3 sites in India
- Volunteers
- 76 people
- Sponsor
- Sudhalkar Eye Hospital
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Intermittent Strabismus, Exotropia Intermittent
Visual Therapy for Intermittent Strabismus
Intermittent strabismus is a condition in which the eyes occasionally become misaligned, affecting binocular vision, depth perception, and quality of life.
- Conditions
- Intermittent Strabismus, Exotropia Intermittent, Esotropia Intermittent
- Trial name
- ViT(I)S (NCT07563959)
- Testing
- Visual Therapy
- Volunteers
- 30 people
- Sponsor
- Universitat Politècnica de Catalunya
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University
Intermittent Exotropia
Trial of Vision Therapy for Intermittent Exotropia
The main objective of this randomized trial comparing vision therapy to observation is to determine the short-term effectiveness of vision therapy on distance intermittent exotropia control.
- Trial name
- VT-IXT (NCT04487249)
- Testing
- Vision Therapy
- Where
- 6 sites in United States
- Volunteers
- 47 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Exotropia
Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia
This study is designed to correct large-angle exotropia by monocular surgery. It compares two augmented recession techniques, which are recession with muscle transplantation and recession with Y splitting.
- Trial name
- NCT07350330
- Testing
- muscle transplantation, Y splitting
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Intermittent Exotropia
Office Based Vergence and Accommodative Therapy and Intermittent Exotropia
This pilot study is designed specifically to determine the short-term effect of OBVAT on intermittent exotropia in terms of 4 key areas (Standardizing reported outcomes of surgery for intermittent exotropia): control score…
- Trial name
- NCT03321838
- Testing
- accommodative/vergence therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sun Yat-sen University