Clinical trials: Exercise Tolerance
Gestational Diabetes
An Exercise Intervention to Prevent Gestational Diabetes
Women diagnosed with gestational diabetes mellitus (GDM) are at substantially increased risk of developing type 2 diabetes and obesity, currently at epidemic rates in the United States.
- Trial name
- NCT00728377
- Testing
- Physical activity, Heath & Wellness
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Massachusetts, Amherst
Heart Transplant
Prospective L-arginine Study
HYPOTHESIS The investigators primary hypothesis is that peripheral endothelial function and exercise tolerance will be abnormal in the population of young heart transplant patients at baseline, and that each will show a trend…
- Trial name
- NCT01485757
- Testing
- L-arginine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Stable COPD Patients
Effect of Vitamin D3 on Lung Function and Exercise Tolerance in COPD Patients
Background: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world which is a preventable as well as treatable disease.
- Trial name
- NCT03781895
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 48 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
COPD
Effect of QVA149 on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study assessed the effect of once-daily indacaterol and glycopyrronium bromide (QVA149) on exercise endurance in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- BRIGHT (NCT01294787)
- Testing
- indacaterol and glycopyrronium bromide (QVA149), tiotropium
- Where
- 13 sites in Germany, Spain
- Volunteers
- 85 people
- Sponsor
- Novartis Pharmaceuticals
COVID-19
Inspiratory Muscle Training in Post COVID-19 Infection Subjects
Long-term COVID has been considered a clinical condition in which the patient, after the critical period of the disease, still has systemic symptoms such as muscle weakness, inability to exercise, sleep disorders and it is still…
- Trial name
- NCT05282199
- Testing
- INSPIRATORY MUSCLE TRAINING
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Universidade Federal de Pernambuco
Dyspnea, Lung Diseases
Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance
The main purpose of this study is to evaluate the effects of automated oxygen administration (FreeO2 system) alone or with high-flow oxygen on dyspnea and exercise tolerance in people with desaturating chronic lung disease…
- Conditions
- Dyspnea, Lung Diseases, Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05267418
- Testing
- Automated nasal O2 titration with FreeO2
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Unsupported Arm Exercise and Breathing Strategy in Patients With Chronic Obstructive Pulmonary Disease
Controlling the way people with lung problems breathe during arm exercises may reduce their breathlessness during activities of daily living that require them to lift their arms (i.e.
- Trial name
- NCT00836108
- Testing
- breathing strategy
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- West Park Healthcare Centre
Chronic Obstructive Pulmonary Disease
Use of an Air Warming Mask for Exercise in Patients With COPD V1.0
The World Health Organisation defines chronic obstructive pulmonary disease (COPD) as 'not one single disease but an umbrella term used to describe chronic lung diseases that cause limitations in lung airflow' covering emphysema…
- Trial name
- NCT02266316
- Testing
- Air warming mask
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Worcester
Breast Cancer, Premenopausal Breast Cancer
Role of Individualized Intervention(s) in Hormone-Receptor Positive Early-stage Breast Cancer
Although combination endocrine therapy has been associated with significant reduction in risk of recurrence in younger women with hormone receptor positive breast cancer, it has been associated with more adverse effects and…
- Conditions
- Breast Cancer, Premenopausal Breast Cancer, Hormone Receptor Positive Tumor
- Trial name
- MyCHOICE (NCT03407768)
- Testing
- Individualized interventions
- Where
- 2 sites in Canada
- Volunteers
- 41 people
- Sponsor
- University of Saskatchewan
Chronic Obstructive Pulmonary Disease
Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPD
Exercise intolerance is a major complain of patients with chronic obstructive pulmonary disease (COPD). Dynamic hyperinflation has been recognized as an important limiting factor responsible for the appearance of intolerable…
- Trial name
- NCT01693003
- Testing
- Indacaterol, Tiotropium
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Impaired Glucose Tolerance
Physical Exercise Versus Rosiglitazone in CAD and Prediabetes
The aim of this study is to prospectively assess the relative benefits of either treatment with rosiglitazone or physical exercise on endothelial function in patients with impaired fasting glucose or impaired glucose tolerance…
- Trial name
- NCT00675740
- Testing
- rosiglitazone, physical exercise, control
- Volunteers
- 45 people
- Sponsor
- University of Leipzig
Blood Pressure, Blood Loss
LBNP Tolerance With Skin Warming After Exercise Cold Stress
Assess the effect of skin rewarming during lower body negative pressure upon arterial blood pressure and tolerance to simulated blood loss after exercise in the cold.
- Trial name
- NCT06279897
- Testing
- Skin Surface Rewarming, Skin Surface Warming, Skin Surface Heating
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Post Thrombotic Syndrome, Venous Thromboses
Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%.
- Conditions
- Post Thrombotic Syndrome, Venous Thromboses, Claudication, Intermittent
- Trial name
- ETERecaVSPT (NCT05794932)
- Testing
- Stress test
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Montpellier
Heart Failure, Congestive, Dyspnea
The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
The purpose of this study is to test the hypothesis that treatment with oral ALT-711 twice daily for 16 weeks will improve aortic distensibility, exercise tolerance, and quality of life in elderly patients with isolated diastolic…
- Conditions
- Heart Failure, Congestive, Dyspnea, Pulmonary Edema
- Trial name
- NCT00043836
- Testing
- ALT-711
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Synvista Therapeutics, Inc
SARS-CoV Infection, Covid19
Muscle Weakness in COVID-19 Patients
Although the Covid-19 infection mainly manifests itself with respiratory symptoms, as early as two months after the onset of the pandemic, the presence of other symptoms, including muscle ones, became clear.
- Conditions
- SARS-CoV Infection, Covid19, Muscle Weakness, Exercise Intolerance
- Trial name
- MIOCOVID (NCT04959773)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Stable Angina Pectoris
Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris
Low intensity shockwaves have been proven in animal and pilot clinical studies to induce local growth of new blood vessels. Small single-center clinical trials with shockwave therapy showed promising results in reducing angina…
- Trial name
- NCT02339454
- Testing
- Active treatment group
- Where
- 2 sites in Lithuania, Russia
- Volunteers
- 72 people
- Sponsor
- Evgeny Shkolnik, MD
End Stage Renal Disease on Dialysis, Hemodialysis Complication
Virtual Reality Intradialysis: Last vs. First Part of the Session
The main objective of this investigation is to assess if an intradialysis virtual reality exercise program during the last two hours of the hemodialysis session results in greater hemodynamic stability than exercise performed…
- Trial name
- VRI (NCT04046042)
- Testing
- Conventional exercise, Exercise during the last two hours of the hemodialysis session
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Overweight/Obesity, Glucose Intolerance
Effects of 3 Months of Supervised Exercise Training
The incidence of type 2 diabetes is increasing worldwide. Because of cardiovascular morbidity and mortality associated with type 2 diabetes, it is imperative to propose methods of prevention and this in early stage of abnormal…
- Conditions
- Overweight/Obesity, Glucose Intolerance, Type 2 Diabetes, Sedentarity
- Trial name
- NCT01349166
- Testing
- Behavior: Supervised physical training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Congestive Heart Failure, Diastole
Aldosterone Antagonism in Diastolic Heart Failure
The primary purpose of this study is to determine whether eplerenone has a beneficial effect on improving exercise ability in patients with diastolic heart failure.
- Trial name
- NCT00108251
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Heart Failure, Ventricular Dysfunction, Left
Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use
The purpose of this study is to determine whether neuromuscular electrical stimulation can improve exercise tolerance for patients with heart failure and continuous dobutamine use in a hospital.
- Trial name
- NCT02668419
- Testing
- Neuromuscular Electrical Stimulator, Physical Therapy Session
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- Federal University of São Paulo