Clinical trials: Ethics
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Cardiac Transplant Disorder
Don't Throw Your Heart Away: Clinician Study 3
Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers.
- Trial name
- NCT04455893
- Testing
- Stratified Transplant Survival
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Educational Activities, Patient Simulation
Clinical Learning Through Extended Immersion in Medical Simulation (CLEIMS)-A New Approach to Teaching Clinical Ethics
Study objective: This study is planning to develop a new simulation-based ethics education model and evaluate the effectiveness of the model to develop medical students' knowledge, moral reasoning, communication skills, and…
- Trial name
- NCT05547893
- Testing
- simulation
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
Study of Decision Making in Patients Participating in Phase I Clinical Trials
RATIONALE: Studying individuals who are enrolled in phase I clinical trials may help to improve the way in which clinical trials are conducted.
- Trial name
- NCT00054223
- Testing
- psychosocial assessment and care
- Where
- 5 sites in United States
- Volunteers
- 250 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cardiac Transplant Disorder
Don't Throw Your Heart Away: Medical Student Study 2
Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers.
- Trial name
- NCT04176796
- Testing
- Stratified Transplant Survival
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
COVID-19
Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients
Evidence has shown that COVID-19 infections can lead to an increased risk of blood clots. These blood clots can lead to individuals being admitted to hospital, or, unfortunately in severe cases, death.
- Trial name
- ETHIC (NCT04492254)
- Testing
- Enoxaparin
- Where
- 3 sites in Australia, Belgium and 1 more
- Volunteers
- 219 people
- Sponsor
- Thrombosis Research Institute
ADHD
Testing a New Method to Improve Informed Consent in Prison Research
Understanding of informed consent is often limited in prison, due to unique challenges faced by detained people. This study will test a modified "teach-to-goal" informed consent process compared to standard procedures.
- Trial name
- Spark BATIR (NCT06378281)
- Testing
- Modified teach-to-goal informed consent
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Stéphanie Baggio
Ethics, Ethical Dilemma
The Impact of Technology-supported Interactive Teaching in Ethics Education
The aim of the study is to determine the effect of technology-supported interactive teaching in ethics education on nursing students' ethical sensitivity and ethical decision-making levels.
- Conditions
- Ethics, Ethical Dilemma, Nursing, Nursing Student
- Trial name
- NCT07502079
- Testing
- Technology-assisted teaching group, Traditional teaching group
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Parental Presence, Pediatric Ethics Consultation
Impact of Parental Presence at the Ethics Meeting in Neonatal Intensive Care
In neonatal intensive care, physicians are sometimes confronted with decisions to withhold or withdraw life-sustaining treatment for a critically ill newborn.
- Trial name
- PaReNCo (NCT07681518)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital NOVO
Narrative Ethics
The Effectiveness of Blended and Problem-based Learning to Improve the Competence of Geriatric Nursing Students
Medical ecology is a highly uncertain and high-pressure environment. Nurses must use their thinking to make critical judgments and decisions in a short time.
- Trial name
- NCT05290909
- Testing
- The protocol of blended and problem-based learning, The traditional problem-oriented teaching model
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Resilience
Exploration of Patient Ethics and Communication Excellence (PEACE) Rounds
A qualitative design using the thematic analysis method is proposed to answer the research question "What is the patient care provider's experience of PEACE rounds?" By establishing salient themes pertaining to the experience and…
- Trial name
- NCT03874676
- Testing
- PEACE Rounds
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- AdventHealth
Liver Diseases, Alcoholic, Alcohol-Related Disorders
Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation
The purpose of this study is to develop a clinical understanding of early liver transplantation (ELT) for patients with severe alcoholic hepatitis (SAH) and identify the public's opinion regarding this practice.
- Conditions
- Liver Diseases, Alcoholic, Alcohol-Related Disorders, Transplant; Failure, Liver, Transplant; Complication, Rejection
- Trial name
- NCT04234139
- Testing
- liver transplant
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Communication, Preoperative
Anesthesia Counseling, Consent, & Professionalism
The anesthesia consent form has become a standard before surgery. However, verbal aspects of anesthesia consent and of the value of the preoperative anesthesia discussion has not been addressed.
- Conditions
- Communication, Preoperative, Ethics
- Trial name
- ACCP (NCT06010836)
- Testing
- Script guided conversation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiac Transplant Disorder
Don't Throw Your Heart Away: Patient Study 4
This empirical study tests whether transplant center performance data that reflect center donor acceptance rates influence patients and their family members to evaluate centers with high organ decline rates less favorably than…
- Trial name
- NCT04809051
- Testing
- Stratified Transplant Survival Metric, SRTR Information Format
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Community Members
Evaluation of Tak Community Advisory Board
A popular form of community engagement is for the researchers to interact with a Community Advisory Board. The Shoklo Malaria Research Unit has been working on the Thai-Burmese border for many years and has been informally…
- Trial name
- NCT01719965
- Testing
- Interviews and Focus Group Discussions
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cognitive Function 1, Social
Wellbeing, Stress Reduction and Social Cognition
There are many ways to improve wellbeing. This study will compare two 8-week wellbeing training programs. In addition to looking at how well the programs reduce stress and enhance wellbeing, the investigators will also ask…
- Trial name
- NCT04494737
- Testing
- Active Comparator: Program 1, Active Comparator: Program 2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cesarean Section
To Compare the Effects of Oxytocin and Carbetocin on Intraoperative Hemodynamic Changes in Cesarean Section Surgeries.
To compare the effects of oxytocin and carbetocin, used as uterotonics in elective caesarean section surgeries, in terms of intraoperative hemodynamic changes.
- Trial name
- NCT06956365
- Testing
- Group-C, Group-O
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Psychotic Disorders
Implementation of Family Involvement for Persons With Psychotic Disorders.
This study will develop and evaluate a complex intervention to implement guidelines on family involvement for patients with psychotic disorders (F20-29 in International Classification of Diseases ICD-10) in community mental…
- Trial name
- IFIP (NCT03869177)
- Testing
- Implementation support program
- Where
- 15 sites in Norway
- Volunteers
- 460 people
- Sponsor
- University of Oslo
Inflammation of Mouth, Acute Mucous Inflammation
Efficacy of Anthocyanin Mouthrinse for Oral Anti-inflammation From Orthodontic Treatment
The purpose of this study is to compare the oral inflammatory reduction effect caused from orthodontic treatment of anthocyanin and placebo mouthrinse.
- Trial name
- NCT02536781
- Testing
- Anthocyanin
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Professional Ethics, Health Communication
Dental Communication and Social Media: Legal and Ethical Framework
This observational study explores the legal and ethical boundaries of dental communication on social media, analyzing Italian regulatory evolution.
- Conditions
- Professional Ethics, Health Communication, Social Media
- Trial name
- NCT07550153
- Testing
- Survey using a questionnaire.
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza