Clinical trials: Erythrocyte Transfusion
Transfusion; Maternofetal
Retrospective Survey of Obstetric Red Cell Transfusion in a Tertiary Women's Hospital
The decision for red cell transfusion is usually made empirically by clinicians. We aim to perform a two-year retrospective audit of obstetric red cell transfusions at a tertairy women's hospital to evaluate the (1) incidence of…
- Trial name
- NCT03738995
- Testing
- Red cell or whole blood transfusion during pregnancy and up to 6 weeks postpartum
- Volunteers
- 760 people
- Sponsor
- KK Women's and Children's Hospital
Extremely Premature Infant, Anemia Neonatal
Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants
Anemia is a condition in which there are not enough red blood cells to carry oxygen throughout the body. It is very common in extremely preterm infants (born before 28 weeks of pregnancy), and many of these babies require red…
- Conditions
- Extremely Premature Infant, Anemia Neonatal, Blood Transfusion, Umbilical Cord Blood
- Trial name
- NCT07502781
- Testing
- Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Hospital Clinic of Barcelona
Pancreatic Surgery
Salvaged Red Blood Cell Transfusion During Pancreatic Adenocarcinoma Operations
The purpose of this study is to prospectively study the safety of salvage red blood cell (sRBC) transfusion during pancreatic surgery. Primary Objective: 1.
- Trial name
- NCT07598357
- Testing
- The Fresenius Kabi C.A.T.S®plus Continuous AutoTransfusion System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Polytrauma, Traumatic Hemorrhage
Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage at Pre-hospital Phase of Care.
This is a single-center, not-randomized, open-label, controlled pilot clinical trial. This study compares presence of Trauma Induced Coagulopathy (TIC) and acute traumatic hemorrhage treatment at pre-hospital phase of care with…
- Trial name
- PRETIC (NCT03780894)
- Testing
- Fibrinogen Concentrate (Human) 1 MG [RiaSTAP], Red blood cells concentrate, Tranexamic Acid
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- Banc de Sang i Teixits
Red Blood Cell Transfusion
Physiologic Effects of RBC Transfusion
The purpose of this study is to determine how red blood cell transfusions, particularly the length of storage time of units of packed red blood cells, affects the cardiovascular function in patients receiving transfusions.
- Trial name
- NCT02566577
- Testing
- Fresh red blood cell (RBC) transfusion, Storage-aged red blood cell (RBC) transfusion, Electronic infusion pump
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Blood Loss, Anemia
Frozen Red Blood Cell Transfusions in Trauma Patients
The purpose of this study is to look at red blood cell (RBC) transfusions in trauma patients and evaluate for any differences between the age of the RBCs and how they were stored.
- Conditions
- Blood Loss, Anemia, Trauma
- Trial name
- NCT01038557
- Testing
- RBC units
- Where
- 5 sites in United States
- Volunteers
- 254 people
- Sponsor
- Oregon Health and Science University
Hemolysis
R-FACT Study:Risk Factors for Alloimmunization After Red Blood Cell Transfusions
Alloantibodies can lead to serious clinical consequences and logistic problems like obtaining properly and timely matched blood for the patients who do develop these antibodies.
- Trial name
- R-FACT (NCT01616329)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Sickle Cell Anemia, Beta-thalassemia Major
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may have on severe sickle cell disease and other transfusion dependent…
- Conditions
- Sickle Cell Anemia, Beta-thalassemia Major, Diamond-blackfan Anemia
- Trial name
- NCT03653338
- Testing
- CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Paul Szabolcs
Brain Tumor Adult, Transfusion
Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR)
To validate a predictive model for the risk of receiving RBCs in this population. This model uses four preoperative values (haemoglobin levels, tumour volume, previous craniotomy in the same spot, and number of craniotomies…
- Conditions
- Brain Tumor Adult, Transfusion, Surgery
- Trial name
- TScoreBTR (NCT05832450)
- Testing
- Red cell concentrate transfusion
- Where
- Spain
- Volunteers
- 1,434 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Anemia of Prematurity (AOP)
Combining Restrictive Guidelines and a NIRS SCORE to Decrease RBC Transfusions
The primary aim of this study is to determine the mean number of red blood cell (RBC) transfusions received by preterm infants cared for using restrictive Hgb guidelines in combination with splanchnic to cerebral oxygenation…
- Trial name
- NCT02535208
- Testing
- Restrictive transfusions based on SCOR assessment, Liberal transfusions
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Transfusion Related Complication
Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver Transplantation
The patients assigned to either short-storage leukoreduced RBCs group (stored for ≤ 14 days) or longer-term storage leukoreduced RBCs group(stored for ≥21 days).When the hemoglobin concentration fell below 7.0 g per deciliter…
- Trial name
- NCT04413721
- Testing
- RBC transfustion
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Red Blood Cell Transfusion
An Innovative Trial Assessing Donor Sex on Recipient Mortality
The iTADS trial will test an important blood donor characteristic - donor sex - to see whether male donor blood leads to a greater benefit for transfusion recipients compared to female donor blood.
- Trial name
- iTADS (NCT03344887)
- Testing
- RBC Transfusion from male donor, RBC Transfusion from female donor
- Where
- Canada
- Volunteers
- 8,850 people
- Sponsor
- Ottawa Hospital Research Institute
Anemia, Cardiac Surgery
Mediation Analysis in Cardiac Surgery
This study investigates the mediating role of intraoperative allogeneic red blood cell transfusion in the relationship between preoperative anaemia and postoperative complications in patients undergoing cardiac surgery.
- Conditions
- Anemia, Cardiac Surgery, Transfusion, Mediation
- Trial name
- MACS (NCT07092683)
- Testing
- anemia, nonanemia
- Where
- China
- Volunteers
- 13,683 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Infant, Premature, Anemia
Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
The purpose of this study was to determine whether restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences.
- Conditions
- Infant, Premature, Anemia, Intracranial Hemorrhages, Leukomalacia, Periventricular
- Trial name
- NCT00369005
- Testing
- Red blood cell transfusion guidelines
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Coronary Artery Disease, Coronary Artery Bypass
Impact of Fluid Restriction Policy in Reducing the Use of Red Cells in Cardiac Surgery
The investigators' hypothesis is that restriction of circulating fluids in comparison to a liberal fluid administration policy would lead to a reduction of allogenic red blood cells exposure in patients undergoing cardiopulmonary…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Erythrocyte Transfusion
- Trial name
- NCT00600704
- Testing
- Fluid Restriction Policy, Free fluid infusion
- Where
- Greece
- Volunteers
- 192 people
- Sponsor
- Larissa University Hospital
Platelet Aggregation, Blood Transfusion
Validation of a Red Blood Cell Transfusion Prediction Model in a Low Transfusion Rate Population.
The transfusion risk and clinical knowledge (TRACK) allogeneic blood transfusion prediction model was developed more than ten years ago and demonstrated good discriminative ability in patients with increased risk for allogeneic…
- Trial name
- TRACK-TCT (NCT05581238)
- Testing
- TRACK-TCT
- Where
- Netherlands
- Volunteers
- 6,428 people, healthy volunteers welcome
- Sponsor
- Medisch Spectrum Twente
Neurosurgery, Orthopedic Surgery
Impact of Tranexamic Acid on Red Blood Cell Transfusion in Spinal Surgery
Spinal surgery may be associated with substantial blood loss which often requires erythrocyte transfusion. Transfusion of red blood cells (RBC) is not free of adverse events and has been associated with increased risks of…
- Conditions
- Neurosurgery, Orthopedic Surgery, Red Blood Cell Transfusion
- Trial name
- NCT01258010
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Necrotizing Enterocolitis of Newborn
The Relationship Between Erythrocyte Transfusion and Nutrition and Necrotizing Enterocolitis in Preterm Infants
In this study; The aim of this study was to investigate the changes in fasting and dietary and mesenteric blood flow in the acute period during and after transfusion and to evaluate the necrotizing enterocolitis.
- Trial name
- NCT04083638
- Testing
- IFAB
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Resectable Pancreatic Carcinoma
Red Blood Cell Transfusion Thresholds for Improved Quality of Life for Patients Undergoing a Pancreatectomy for Pancreatic Cancer
This clinical trial tests the the feasibility of testing a red blood cell transfusion threshold for improved quality of life for patients undergoing a pancreatectomy for pancreatic cancer.
- Trial name
- NCT05841706
- Testing
- Arm I Packed Red Blood Cell Transfusion (Hgb < 7 g/dL), Arm II Packed Red Blood Cell Transfusion (Hgb < 9 g/dL), Computed Tomography
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Red Blood Cell Transfusion, Oxygen Consumption
Assessment of Oxygen Extraction Rate Changes Following Red Blood Cell Transfusion in the Intensive Care Unit
Restrictive and liberal approaches to hemoglobin targets are used when deciding on red blood cell transfusions in patients who do not have acute bleeding and have a hemodynamically stable course in the intensive care unit.
- Trial name
- NCT05798130
- Testing
- No intervention group.
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Izmir Katip Celebi University