Clinical trials: Erythema, open to volunteers
Erythema Migrans
Patient's Pretreatment Expectations About Post-Lyme Symptoms
The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a…
- Trial name
- NCT03462329
- Testing
- Antibiotics (preferentially oral doxycycline 100 mg bid)
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Migrans of Lyme Disease
Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis))
The aim of this study is to assess the effect of Saccharomyces boulardii CNCM I-745 on gut microbiota in patients undergoing antibiotic therapy (in the context of erythema migrans (early skin form of Lyme borreliosis)).
- Trial name
- SUBLYME (NCT06451913)
- Testing
- Amoxicillin + Saccharomyces boulardii CNCM I-745, Stool samples, BSFS : Bristol Stool Form Scale
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- Biocodex
Rosacea
Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea
Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness.
- Trial name
- NCT06312813
- Testing
- Imipramine, Amitriptyline, Vehicle
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wright State University
Carpal Tunnel Syndrome
Efficacy of Red Kinesiology Tape on Carpal Tunnel-Like Symptoms and Performance in Esports Gamers
The goal of this clinical trial is to learn if dorsally applied kinesiology tape is an effective conservative treatment for symptoms of carpal tunnel syndrome and assess the potential performance effect of the tape color in…
- Trial name
- NCT06757062
- Testing
- Kinesiology Tape
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Nevada, Las Vegas
Cradle Cap, Seborrheic Dermatitis
TRIDERM D.S. Crema Normalizzante for Neonatal Hyperseborrhea (Cradle Cap) and Associated Cutaneous Manifestations of Mild-to-Moderate Seborrheic Dermatitis in Children Aged 0 to 3 Years
This clinical study aims to evaluate the effects of using the cosmetic product TRIDERM D.S. Crema Normalizzante in children aged 0 to 3 years with neonatal hyperseborrhea ("cradle cap"), potentially associated with manifestations…
- Trial name
- NCT07860788
- Testing
- TRIDERM D.S. Crema Normalizzante
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- ICIM International S.r.l.
Perianal Abscess
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery.
- Trial name
- NCT07155356
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 222 people
- Sponsor
- The Affiliated Hospital of Putian University
Erythema Chronicum Migrans
Duration of Doxycycline Treatment in MEM Patients
The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with multiple erythema migrans.
- Trial name
- NCT03337932
- Testing
- Doxycycline 100 milligram Oral Tablet bid, 7 days, Doxycycline 100 milligram Oral Tablet bid, 14 days, Controls without a history of lyme disease.
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Ostomy - Ileostomy or Colostomy, Stoma Complications
Suture Choice for Ostomy Creation
The goal of this clinical trial is to learn whether chromic gut or polyglactin 910 suture results in fewer stoma complications when used to mature an enterostomy in patients undergoing planned ostomy creation.
- Conditions
- Ostomy - Ileostomy or Colostomy, Stoma Complications, Stoma Site Dermatitis, Stoma Site Infection
- Trial name
- NCT07900711
- Testing
- Chromic Gut Suture, Polyglactin 910 Suture
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Southern California
Psoriasis
An AI-Based Erythema Measurement System for Psoriasis Lesions
Psoriasis is a common chronic inflammatory skin disease. Disease severity is commonly assessed using the Psoriasis Area and Severity Index (PASI), in which erythema is graded subjectively on a 0-4 scale.
- Trial name
- NCT07494396
- Testing
- No additional drugs(control Group)
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Khon Kaen University
Post Inflammtory Erythema, Acne Vulgaris
Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris
Post-inflammatory erythema (PIE) is a common sequela of acne vulgaris, characterized by persistent erythematous macules resulting from superficial vascular dilation.
- Conditions
- Post Inflammtory Erythema, Acne Vulgaris, Erythema
- Trial name
- NCT07474883
- Testing
- Timolol 0.5% Ophthalmic Solution, Intense Pulsed Light
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Toxic Epidermal Necrolysis, Immunotherapy
New Therapeutic Target for Toxic Epidermal Necrolysis (TEN) Using Anti-CD38+ Monoclonal Antibodies.
Toxic Epidermal Necrolysis (TEN) are rare diseases that are dermatologic emergencies characterized by widespread epidermal necrosis and sloughing of skin. A hundred patients are affected each year in France.
- Conditions
- Toxic Epidermal Necrolysis, Immunotherapy, Cutaneous Adverse Drug Reactions (CADR)
- Trial name
- NET-CD38 (NCT07110662)
- Testing
- DARATUMUMAB (DARZALEX®)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Hospices Civils de Lyon
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation
Erythema, Telangiectasis
The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Facial Erythema and Other Skin Parameters
The aim of this study is to compare the effects of 16 weeks of daily dietary supplementation with two investigational products containing collagen, methylsulfonylmethane (MSM), and vitamin C on skin parameters in comparison to a…
- Conditions
- Erythema, Telangiectasis, Skin Redness
- Trial name
- TO-COSKIN4 (NCT07345195)
- Testing
- CPMSM-HD, CPMSM-LD
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Breast Cancer, Axillary Lymph Nodes
Using LUminoMark vs Coventional Practice for Targeted Axillary Surgery
The purpose of this study was to compare the use of LuminoMarkTM as a method of targeting axillary lymph nodes with other existing methods used in each institution, such as charcoal staining, needle targeting, and…
- Conditions
- Breast Cancer, Axillary Lymph Nodes, Target Lesion
- Trial name
- LUCAS (NCT06903429)
- Testing
- Targeting of axillary lymph nodes using LuminoMark, Targeting of axillary lymph nodes using conventional method
- Volunteers
- 330 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Ocular Hyperemia
Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults
The purpose of this study is to evaluate the efficacy and safety of an investigational ophthalmic solution in adults with ocular redness due to minor eye irritations.
- Trial name
- NCT07531043
- Testing
- Apraclonidine Ophthalmic Solution, 0.125% Unit Dose Preservative Free, Vehicle
- Where
- 9 sites in United States
- Volunteers
- 230 people
- Sponsor
- Alcon Research
Erythema Migrans
Different Amoxicillin Treatment Regimens in Erythema Migrans Patients
The purpose of this study is to compare the efficacy of different amoxicilline treatment regimens in patients with erythema migrans.
- Trial name
- NCT03966014
- Testing
- EM-amoxicillin 3 x 10 days, EM-amoxicillin 3 x 14 days, Controls
- Where
- 2 sites in Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Penetrating Keratoplasty, Multiple Graft Failure
Subconjunctival Humira for Boston Keratoprosthesis
This trial is studying the safety and tolerability of receiving an injection of adalimumab (Humira) during the Boston Keratoprosthesis (KPro) surgery.
- Conditions
- Penetrating Keratoplasty, Multiple Graft Failure, Ocular Cicatricial Pemphigoid, Stevens-Johnson Syndrome
- Trial name
- NCT06926478
- Testing
- Adalimumab Injection
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Epidermis, Ultraviolet Exposure
A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use
Approximately 70 subjects (35 subjects per light and dark group) will be enrolled in this clinical study (to complete with a minimum of 10 subjects per skin type (I-VI) to assess the effects of known UV Radiation dosage on light…
- Trial name
- NCT07789639
- Testing
- Hybrid sunscreen, Chemical sunscreen, No sunscreen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Good Molecules, LLC
Parvovirus B19 Infection, Pregnancy
Parvovirus B19 Infection in Pregnancy: Clinical Manifestations and Fetus/Newborn Outcome
The goal of this observational study is to define the rate of intrauterine parvovirus B19 infection and fetal/newborn complications after parvovirus B19 infection of pregnant women.
- Trial name
- ParvoPre (NCT07338279)
- Testing
- Collection of clinical data.
- Where
- 5 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Erythema Nodosum Leprosum
Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction
Dovramilast has not been approved for leprosy type 2 reaction (erythema nodosum leprosum, ENL) or any other disease anywhere in the world.
- Trial name
- NCT07172659
- Testing
- Dovramilast, Prednisolone, Thalidomide
- Where
- 6 sites in United States, Benin and 4 more
- Volunteers
- 45 people
- Sponsor
- Medicines Development for Global Health