Clinical trials: Erythema
Stevens-Johnson Syndrome, Kidney Failure, Chronic
HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction
Allopurinol-induced severe cutaneous adverse reaction (SCAR) is a rare but fatal condition. Previous reports have reported that HLA-B*5801 is an important genetic risk factor significantly associated with the development of…
- Trial name
- NCT03046914
- Testing
- HLA-B*5801 test
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Seoul National University Hospital
Rosacea
Efficacy of IPL, an Anti-redness Dermocosmetic, and Their Combination in the Treatment of Rosacea
This study compares three approaches to treating persistent facial redness in adults with erythematotelangiectatic rosacea: intense pulsed light (IPL) treatment alone, a professional anti-redness dermocosmetic skincare regimen…
- Trial name
- NCT07729540
- Testing
- Intense Pulsed Light (IPL) - Lumecca, Rosacure anti-redness dermocosmetic regimen
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Nociceptive Pain, Musculoskeletal Pain
Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain
This is a trial to measure the effectiveness and safety of the invisa-RED® IR REHAB device. The researchers will compare the muscle and joint pain relief of participants who are treated with the real machine, to those treated…
- Trial name
- NCT06393088
- Testing
- IR REHAB
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- IR Technology, LLC
Wrinkles, Ageing
Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin
Objective of the study is to determine the influence of dietary supplementation with coenzyme Q10 (CoQ10) on skin conditions. 33 healthy female subjects will be randomly assigned to a placebo group, a low-dose (LD) group…
- Conditions
- Wrinkles, Ageing, Photoprotection
- Trial name
- NCT02604641
- Testing
- Quvital LD group, Quvital HD group
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Erythematotelangiectatic Rosacea, Papulopustular Rosacea
Open Label Pilot Study of Apremilast in Treatment of Rosacea
Rosacea is a chronic skin disorder with the signs and symptoms of facial flushing, persistent redness, small visible spider-like veins, papules (inflamed red bumps under the skin) and pustules.
- Trial name
- NCT01045551
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Julian M. Mackay-Wiggan
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865094
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Lyme Borreliosis
Doxycycline in Therapy of Erythema Migrans
The investigators will compare the outcome of three groups of erythema migrans patients treated with doxycycline: a group without any accompanying symptoms, with mild symptoms and with severe symptoms that require lumbar puncture.
- Trial name
- NCT01475708
- Testing
- Doxycycline
- Where
- Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema, Pain
Ultra Violet B Radiation (UVR) Study of Strontium Chloride Hexahydrate Hydrocortisone
Double blinded (subject and observer), randomised, active (hydrocortisone (HC)) controlled study of the effect of strontium chloride hexahydrate on ultraviolet B radiation (UVR) induced signs of inflammation (erythema and pain)…
- Trial name
- NCT01301677
- Testing
- Hydrocortisone, 2PX+, 2PX-
- Where
- 2 sites in Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- X-pert Med GmbH
Erythema, Radiation Therapy, Secondary Skin Reactions
Evaluation of a Novel Amino Acid Based Moisturizing Cream as Part of the Daily Standard Skincare Regimen Recommended During Radiation Therapy
The goal of this clinical study is to evaluate a novel amino acid based moisturizing cream as part of the daily standard skincare regimen recommended during radiation therapy.
- Trial name
- NCT06016361
- Testing
- VS-200Cr, Standard of care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Entrinsic Bioscience Inc.
Rosacea
Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness
The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.
- Trial name
- NCT01529996
- Testing
- Pulse Dye Laser/YAG laser
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Rosacea
Comparative Safety and Efficacy of Two Rosacea Products in the Treatment of Facial Erythema of Rosacea
To compare safety and efficacy of Perrigo's rosacea drug product compared to an FDA approved rosacea drug product in the treatment of facial erythema of rosacea.
- Trial name
- NCT02385240
- Testing
- Brimonidine Topical Gel, 0.33 percent (Perrigo), Brimonidine Topical Gel, 0.33 percent (Reference)
- Volunteers
- 552 people
- Sponsor
- Padagis LLC
Erythema Nodosum Leprosum, Leprosy
Montelukast in ENL Reaction
Objective of the trial is to assess the safety and efficacy of Montelukast in treatment of Erythema Nodosum leprosum (ENL) reaction in multibacillary leprosy patients either in combination with prednisolone or alone.
- Trial name
- NCT00406861
- Testing
- montelukast in treatment of ENL reaction
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- The Leprosy Mission Bangladesh
Leprosy
Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in ENL
Erythema nodosum leprosum (ENL) is characterized by painful nodules and systemic compromising. It is usually recurrent and/or chronic and has both physical and economic impact on the patient, being a very important cause of…
- Trial name
- NCT07806357
- Testing
- Efficacy and Safety of Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in Erythema Nodosum Leprosum (Type 2 Lepra Reaction)
- Where
- Bangladesh
- Volunteers
- 19 people
- Sponsor
- Chittagong Medical College
Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum
Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
This study investigates the genetic architecture of Neutrophil-Mediated Inflammatory Skin Diseases. After collecting informed consent, all patients' clinical phenotype is graded at inclusion with a detailed case report form and a…
- Conditions
- Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum, Erosive Pustular Dermatosis of the Scalp, Sweet's Syndrome
- Trial name
- NEUTROGENE (NCT01952275)
- Testing
- Collection of biological samples
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University of Zurich
Erythema Migrans
Lyme Borreliosis and Early Cutaneous Diagnostic
Test and evaluate a new diagnostic method (SRM-MS/MS: Selected Reaction Monitoring- Mass spectrometry) for Lyme Borreliosis on human skin biopsies. Patients included are those with the early skin manifestation (erythema migrans).
- Trial name
- DIABOLYC (NCT02414789)
- Testing
- Skin biopsies
- Where
- 7 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Strasbourg, France
Erythema, Sun Damaged Skin
Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
The aim of this study is to determine the erythema-reducing efficacy of a test product in two concentrations on a light sunburn induced by a sun simulator compared to an untreated control and a placebo product.
- Conditions
- Erythema, Sun Damaged Skin, Skin Inflammation
- Trial name
- NCT05300542
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Seasonal Allergic Rhinitis
A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
The objective of the study was to determine the efficacy and tolerability of 20 mg of Bilastine, compared to Desloratadine and placebo for the treatment of Seasonal Allergic Rhinitis.
- Trial name
- NCT01108783
- Testing
- Bilastine, Desloratadine
- Volunteers
- 720 people
- Sponsor
- Faes Farma, S.A.
Ocular Redness
A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness
To demonstrate the efficacy of BTOS-HA as non inferior to Lumify for treating ocular redness in a population of adult subjects.
- Trial name
- NCT06803654
- Testing
- BTOS-HA, Lumify®
- Where
- 11 sites in United States
- Volunteers
- 578 people
- Sponsor
- Bausch & Lomb Incorporated
Altitude, Ultraviolet Rays
Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude
With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses.
- Conditions
- Altitude, Ultraviolet Rays, Antioxidants, Oxidative Stress
- Trial name
- NCT00685438
- Where
- Nepal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Oral Hygiene, Photographs
Effect of Pre-treatment Photographs on Oral Hygiene Maintenance in Orthodontic Patients
Dental photography is an essential component of orthodontic treatment. Photographs enable the clinician to keep record of different stages of treatment.
- Trial name
- NCT06010797
- Testing
- Showing Pre-treatment photographs of the patient
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehmat Memorial Post Graduate Dental Teaching Hospital